病原体相关分子模式

Toll样受体是一类在进化中高度保守的Ⅰ型跨膜蛋白，识别病原体相关分子模式，为先天性免疫的重要成分，同时在机体特异性免疫过程中也起着关键性作用。

Toll like receptor is a kind of type I transmembrane protein , which is high conservative evolutionally . Toll like receptor is one of the most important components of innate immunity by recognizing different pathogen associated molecular pattern .

天然免疫系统主要依赖于通过感知病原体相关分子模式（pathogen-associatedmolecularpatterns，PAMPs）的蛋白质识别病原体。

The innate immune system recognizes invading pathogens by sensing pathogen-associated molecular patterns ( PAMPs ) proteins .

Toll样受体（TLRs）作为识别病原体相关分子模式的关键天然免疫受体，在宿主防御系统中发挥重要作用。

Toll-like receptors ( TLRs ), which function as key innate immune receptors responsible for recognizing PAMPs , play essential roles in the host defense system .

Toll样受体（Toll-Likereceptors，TLRs）家族识别病原体相关分子模式（PAMPs）从而启动固有免疫应答，属于模式识别受体（PRRs）。

Toll-like receptors ( TLRs ), a family of pattern recognition receptors , recognize the pathogen-associated molecular patterns ( PAMPS ) to initiate the innate immunity .

天然免疫系统通过一系列高度保守的模式识别受体识别病原体相关分子模式。

The innate immune system recognizes pathogen associated molecular patterns through a series of pattern recognition receptors .

天然免疫系统通常籍模式识别受体识别病原体相关分子模式。

Pathogen recognition by the innate immune system is commonly based on the identification of pathogen-associated molecular patterns by the pattern-recognition receptors .

作为微生物细胞壁成分及一种病原体相关的分子模式，LPS可以激活先天免疫。

As one of pathogen-associated molecular patterns ( PAMPs ), LPS ( lipopolysaccharide ) can be recognized by antigen-presenting cells ( APC ) including macrophages and then activate innate immune response .

外来入侵病原体的识别由病原体相关分子模式（PAMP）介导，这类分子模式能被模式识别受体（PRR）所识别。

Detection of foreign intruders is mediated by pathogen-associated molecular patterns ( PAMP ) that are recognized by pattern recognition receptors ( PRRs ) .

在启动先天免疫对抗病原体的过程中最重要的一步就是识别，由杀伤细胞的受体识别存在于病原体而不存在于细胞中的成分，这称为病原体相关分子模式（pathogen-associatedmolecularpattern，PAMP）。

The most significant step in the process of initiating innate immunity to resist pathogens is recognition , the components , exist in pathogens instead of in cells , which is called pathogen-associated molecular pattern ( PAMP ), can be recognized by the receptors of killing cells .