甲基强的松龙
- 名Methylprednisolone
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大剂量维生素C与小剂量甲基强的松龙联合治疗大鼠急性脊髓损伤初步研究
The effects of therapy with high-dose Vitamin C combined with low-dose methylprednisolone for acute spinal cord injury in rat
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目的探讨损伤前应用甲基强的松龙(MP)对脊髓损伤的影响。
Objective To investigate the effect of methylprednisolone administrated before spinal cord injury .
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反相HPLC法测定血浆中的氢化可的松和甲基强的松龙
Determination of Hydrocortisone and Methylprednisolone in Plasma by Reversed & P has e HPLC
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B组:15只,连续3d腹腔内注射甲基强的松龙45mg/kg。
Group B ( 15 ) was received an intraperitoneal injection of 45 mg / kg of methylprednisolone acetate for three consecutive days .
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提示:经胸电击可升高PT,降低IDA;甲基强的松龙可减轻这种作用。
Methylprednisolone can reduce the effect of shock on PT and IDA .
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目的研究注射用甲基强的松龙的应用剂量对重症SARS患者的疗效和不良反应的影响。
Aim To study the effect and ADRs of metrisone dosage to critical patients of SARS .
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MMP-9、TIMP-1在实验性自身免疫性肌炎中的表达及甲基强的松龙的影响
The expression of MMP-9 and TIMP-1 in EAM and the effects of methylprednisolone
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目的研究大剂量Vitaminc对大鼠急性脊髓损伤(SCI)疗效并与甲基强的松龙(MP)相比较。
Objective To investigate the therapeutic effect of high-dose Vitamin C on acute spinal cord injury ( SCI ) in rats .
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目的观察心肌缺血再灌注时心肌细胞核因子-κB(NF-κB)活性的变化以及甲基强的松龙对心肌缺血再灌注损伤的影响。
Objective To study the changes of nuclear factor-kappa B ( NF - κ B ) and cytokines in myocardial Ischemic / Reperfusion injury during cardiopulmonary bypass ( CPB ) .
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目的采用大剂量甲基强的松龙冲击治疗小儿急性肺损伤(ALI),评价其疗效。
Objective There are different opinions on large dose methylprednisolone impact therapy for acute lung injury .
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目的观察甲基强的松龙对大鼠颅脑损伤后血、脑组织中NOS含量的影响,并探讨其作用机制。
Objective To observe the role of methylprednisolone by change of NOS level in rat brain trauma tissue .
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甲基强的松龙对狼疮性肾炎患者血浆中PAI-1的影响
Methylprednisolone 's influence on the plasma plasminogen activator inhibitor-1 in lupus nephritis patients
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甲基强的松龙对香烟烟雾提取物诱导A549细胞I-κBα的影响
The Alteration of I - κ B α induced by cigarette smoke extract and effect of Methylprednisolone in the human pulmonary cell type ⅱ
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目的探讨依次采用少量血浆交换、大剂量丙种球蛋白、大剂量甲基强的松龙治疗重症肌无力(MG)Ⅱb或Ⅲ型的临床疗效及安全性。
Objective To explore the clinic effect and reliability Treated with a little plasma exchange ? large dosage beriglobin and large dosage methylprednisolone in myasthenia gravis ( MG )ⅱ b or III.
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治疗组40例给予甲基强的松龙1~2mg/(kg·次),轻度哮喘1次静滴,中、重度2次/d静滴;
Forty cases received methylprednisolone 1 ~ 2 mg / kg , once a day for the light cases , twice a day for the secondary or the heavy ones .
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甲基强的松龙对深低温脑缺血再灌注大鼠脑组织S-100β蛋白表达的影响
Influence of methylprednisolone on the expression of S-100 beta protein after deep hypothermia cerebral ischemia reperfusion in rats
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甲基强的松龙对脑损伤大鼠血清神经组织蛋白S100和神经元特异性烯醇化酶的影响
Effects of methylprednisolone on serum S-100B protein and neuron specific enolase in rats with brain injuries
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研究目的:观察小剂量抑肽酶及甲基强的松龙对体外循环(CPB)炎性反应的影响。
Objective : To observe the effects of low-dose aprotinin and methylprednisolone on the inflammatory response induced by cardiopulmonary bypass ( CPB ) .
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目的:研究大剂量甲基强的松龙(MP)治疗急性脊髓损伤的临床效果。
Objective : To investigate the clinic effects of high dose of methylprednisolone ( MP ) on acute spinal cord injury ( ASCI ) .
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但三种浓度的甲基强的松龙(0.05μM、0.10μM、0.15μM)对AM分泌IL-6均无显著抑制作用。
But all three concentrations of methylprednisolone ( 0.05 μ M , 0.10 μ M , 0.15 μ M ) did not significantly reduce LTB4 release by AM .
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甲基强的松龙对伽玛刀照射后胶质细胞Cx43和GFAP表达的影响
The effects of methylprednisolone on expressions of connexin 43 and GFAP in cultured rat astrocytes after irradiation by gamma knife
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方法30例择期行双瓣膜置换的病人,随机均分为三组:肝素化膜肺组(H组)、甲基强的松龙组(M组)和对照组(C组)。
Methods Thirty adult patients undergoing elective dual valves replacement were randomly divided equally into three groups : heparin-bonded membrane oxygenator ( group H )、 methylprednisolone group ( group M ) and control group ( group C ) .
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实验组予耳缘静脉注射马血清(10ml/kg)2次,每次间隔2周;马血清注射完毕2周后,连续3d腹腔内注射甲基强的松龙(45ml/kg·d)。
The experimental group was given 10 ml / kg of horse serum intravenously 2 times at 2 weeks intervals and an intraperitoneal injection of 45 ml / kg · d of methylprednisolone acetate for 3 days ;
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结论:脊髓损伤后脊髓CFos基因表达显著增多,甲基强的松龙能抑制损伤后CFos基因表达。
Conclusion C fos gene expression in rat spinal cord can be markedly enhanced by injury , and MP may play a role in inhibition of c fos gene expression during injury .
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结论早期大剂量运用甲基强的松龙,能够抑制失血性休克后肠组织ICAM-1的表达,减轻肠结构的破坏,保护肠粘膜屏障功能。
Conclusion Methylprednisolone can inhibit the expression of ICAM-1 in intestinal tissue and has potential protective effects on the intestinal barrier function after hemorrhagic shock .
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结论HBO与甲基强的松龙均可明显抑制T细胞亚群及其粘附分子的表达,且两者具有协同作用。
Conclusions Both HBO and ME prednisolone could inhibit markedly the activities of T lymphocyte and its CAMs expression and besides they have synergetic effect .
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目的:探讨甲基强的松龙(MP)对大鼠急性脊髓损伤组织C9,CD59表达的影响。
AIM : To discuss the effects of methylprednisolone on C9 and CD59 expression in rat acute spinal cord injury tissue .
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目的:研究大剂量维生素C(VitC)+小剂量甲基强的松龙(MP)对大鼠急性脊髓损伤(SCI)的疗效。
Objective : To investigate the effects of therapy with high-dose Vitamin C ( Vit C ) combined with low-dose methylprednisolone ( MP ) in acute spinal cord injury ( SCI ) .
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甲基强的松龙对EAE大鼠脑组织Nogo-A及其受体NgR蛋白的影响
The Expression of Nogo-A and Its Receptor NgR Protein in the Brain of Eae Rat Treated with Methylprednisolone
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与静脉应用甲基强的松龙相比,血浆置换使发病时伴有肾衰的ANCA相关性系统性血管炎患者肾脏恢复比例增加。
Plasma exchange increased the rate of renal recovery in ANCA-associated systemic vasculitis that presented with renal failure when compared with intravenous methylprednisolone .