甘遂

甘遂中巨大戟萜醇型二萜酯类化学成分的研究

Studies on ingenol-type diterpene esters in root tuber of Euphorbia kansui

对应受谴责的行为有责任或者可以控诉；以罪行为特点。甘遂对胃肠平滑肌的作用特点及其用于质量控制指标的可行性

Responsible for or chargeable with a reprehensible act ; or marked by guilt . Euphorbia Kansui Effect on Gastro-intestinal Smooth Muscle and Possibility for its Quality Control Based on its Clinical Application

基于大鼠肝脏微粒体细胞色素P450酶系的甘遂和甘草配伍作用研究

Research of Euphorbia Coadministration with Glycyrrhiza Based on Cytochrome P450 in Rat Liver Microsomes

AHNP内毒素预处理加甘遂治疗组。

Group of endotoxin pretreatment and Kansui treatment of AHNP .

目的：甘遂为大戟科植物甘遂EuphorbiaKansuiT.N.LiouexT.P.Wang的干燥块根。

Objective : The kansui roots were Euphorbia kansui T. N. Liou ex T. P. Wang , belongs to Euphorbiaceae Euphorbia kansui .

【目的】探讨甘遂对重症急性胰腺炎（SAP）患者血清TNF-αI、L-6水平的影响，为其在临床广泛应用提供研究基础。

【 Objective 】 To study the effect of kansui root on serum TNF - α and IL-6 levels in patients with severe acute pancreatitis ( SAP ), and offer the theoretical base for its clinical use in treating SAP .

结论重症急性胰腺炎时有COX-2的高表达和TXA2/PGI2之间的失衡，甘遂可以下调COX-2的表达，纠正TXA2/PGI2之间的失衡，而改善胰腺微循环。

Conclusions There was high expression of COX-2 and imbalance between TXA_2 and PGI_2 in SAP rats . Kansui root may reduce the expression of COX-2 and by correction of the imbalance ( between ) TXA_2 and PGI_2 which can improve the microcirculation of pancreas .

甘遂治疗重症急性胰腺炎的系统评价

Kansui Root for Treating Severe Acute Pancreatitis : A Systematic Review

甘遂提取液对家兔离体子宫平滑肌作用的观察

Effect of extract fluid from Gansui on rabbit uterine deviated from body

甘遂块根的发育解剖学研究

The developmental anatomy on the root tuber of Euphorbia kansui

初步探讨了甘遂醋炙后减毒的炮制机理。

Preliminary studied the mechanism of attenuation processing raw kansui root by vinegar .

结论：甘遂炮制以30%醋制为佳。

Conclusion : Gansui should be prepared with vinegar of 30 % concentration .

不同构型酒石酸对大麦铝毒害的缓解效应大枣缓解甘遂毒性部位致炎作用的效应

Alleviating effect of different configuration tartaric acids on aluminum toxicity in barley seedlings

甘遂醇提物中4种二萜类化合物的体内抗病毒活性研究

Study on in vivo antiviral activity of four diterpenoids from ethanol extracts of Euphorbia kansui

方法：以柱层析对甘遂醇提物初步分离。

Methods : Initial separation of ethanol extract from Euphorbia kansui was performed by column chromatography .

甘遂乳汁管的解剖学及营养器官中二萜类化合物分布的研究

Studies on anatomy of laticifers and localization of diterpene esters in vegetative organs in Euphorbia kansui

目的对比研究甘遂和大黄辅助治疗重症急性胰腺炎的作用。

The Clinical Observation on the Effect of Gansui in Treating Acute Urinary Retention Caused by BPH ;

甘遂对胃肠平滑肌的作用特点及其用于质量控制指标的可行性

Euphorbia Kansui Effect on Gastro-intestinal Smooth Muscle and Possibility for its Quality Control Based on its Clinical Application

甘遂组织化学实验结果显示二萜类化合物在甘遂的营养器官中分布广泛。

The histochemical results showed that the diterpene esters were distributed widely in the vegetative organs of E. kansui .

甘遂乳汁管的分布、发育与超微结构以及6种大戟属植物的比较研究

The Distribution , Development and Ultrastructure of Laticifers in Euphorbia Kansui and the Comparative Studies of Six Euphorbia Species

正交试验法优选白芥子延胡索甘遂合并提取的工艺

An Orthogonal Test for Optimization of Procedure of Extracting Procedure to Semen Sinapis Albae , Rhizoma Corydalis and Radix Kansui

目的：探讨中药甘遂辅助性治疗重症急性胰腺炎的作用及机理。

Objective : To study of auxiliary therapeutic effect and its mechanism of kansui root on patients with severe acute pancreatitis .

结果：甘遂醋制后毒性明显降低，利尿作用有所缓和；

Result : The toxicity of Gansui was reduced after prepared with vinegar , and the effect of diuresis was alleviated .

甘遂根茎叶的发生过程，与多年生双子叶草本植物的一般发育规律相类似。

The developing process of root , stem and leaf of E. kansui were similar to the normal developing principles of other dicotyledons .

内毒素对急性出血坏死性胰腺炎早期细菌易位的影响及甘遂治疗作用的实验研究

The effects of endotoxin and kansui on the bacteria and endotoxin translocation in the early stage of acute hemorrhagic necrotic pancreatitis in rat

目的考察甘遂和醋甘遂乙醇提取物及其不同极性部位的泻下作用和毒性。

Objective To study the effect of the ethanol extracts from different polar parts of kansui and vinegar-preparing kansui on purgative activity and acute toxicity .

以小鼠作为受试对象，对甘遂生品及醋炙品炮制前后有效部位提取物分别进行小肠推进实验和急性毒理实验。

Used mice as target subjects , to experimental raw and kansui root by vinegar extracts with adopt the small intestine propulsion and acute toxicological experiment .

结论：甘草与甘遂、大戟、海藻、芫花药物配伍后对大鼠心肝肾有一定毒副作用。

CONCLUSION : There are certain toxic side effects in heart , lever and kidney if liquorice are combining with kansui root , spurge , seaweed or lilac Daphne flower bud .

目前，对于甘遂的研究主要集中在化学成分、药理作用和临床应用等方面，而关于甘遂乳汁的蛋白质组学研究至今没有报道。

At present , most studies about E. kansui had mainly focused on their chemical components analysis , pharmacology and clinical applications . As far , proteomics research of Euphorbia kansui has not been reported .

这表明甘遂引产机理可能是甘遂造成子宫内前列腺素的合成与释放增加，前列腺素刺激子宫肌收缩而导致流产。

The results Showed that mechanism of midtrimester abortion induced by Euphorbia kansui injection may be that the Euphorbia kansui injection makes the increases of endogenous prostaglandins production , the prostaglandins stimulate the contractions of uterine muscles , thus result in abortion .