甘草酸二铵

目的研究甘草酸二铵（DG）对染镉小鼠肝脂质过氧化损伤的保护作用。

Objective To study the protecting effect of diammonium glycyrrhizinate ( DG ) on cadmium-induced lipid peroxidation in liver of mice .

目的：观察在综合治疗的基础上联合应用前列腺素E1脂微球（Lipo-PGE1）注射液和甘草酸二铵注射液治疗重型肝炎的疗效。

OBJECTIVE : To observe the clinical outcome of lipid microspheres prostaglandin E 1 ( Lipo-PGE 1 ) injection in combination with diammonium glycyrrhizinate injection plus combined therapy in the treatment of chronic severe hepati-tis .

目的：探讨甘草酸二铵治疗拉米夫定致HBV变异后的肝功能异常的疗效。

Objective : To observe diammonium glycyrrhizinate for impaired liver function due to lamivudine-induced HBV mutation .

甘草酸二铵治疗拉米夫定致HBV变异后的肝功能异常

Effects of diammonium glycyrrhizinate on impaired liver function associated with hepatitis B virus mutation to lamivudine

18α-甘草酸二铵对大鼠肝脏细胞色素P450和II相酶的影响

Effects of 18 α - glycyrrhizic acid on rat liver cytochrome P450 isoenzymes and phase II transferase

结果甘草酸二铵组较对照组病死率明显下降，差异具有高度显著性（P0.01）；

Results The disease mortality of diammonium glycyrrhizinate group decreased more significantly than that of control group ( P0.01 ) .

目的通过人工抗原的构建，制备抗甘草酸二铵（DG）的特异性抗血清。

Objective To construct artificial immunogen and prepare specific antiserum of diammonium glycyrrhizinate ( DG ) .

甘草酸二铵组和对照组较治疗前TNFα浓度均降低，且第3天开始出现甘草酸二铵组较对照组TNFα减少更明显（P0.05），第7天减少进一步明显（P0.01）。

The concentration of serum TNF α of diammonium glycyrrhizinate group decreased much more obviously than control group at 3 day ( P0.05 ) and 7 day ( P0.01 ) .

目的研究18α甘草酸二铵（18αGL）对肝脏药物代谢酶的影响。

AIM To study the effect of 18 α glycyrrhizic acid ( 18 α GL ) on hepatic microsomal drug metabolizing enzymes in rats .

结论甘草酸二铵对MODS有较好的治疗作用，可明显减少炎症因子TNFα的释放，改善APACHEⅢ评分、MODS评分情况，降低MODS的病死率。

Conclusion Diammonium glycyrrhizinate against MODS has better therapy effect by decreasing the release of inflammation gene TNF α, improving APACHE ⅲ scores and MODS scores , and decreasing disease mortality .

目的考察甘草酸二铵（GA）注射液分别与注射用还原型谷胱甘肽、维生素K1注射液配伍后在5%葡萄糖注射液（GS）和5%木糖醇注射液中的稳定性。

Objective To study the stability of glycyrrhizic acid diammonium salt injection mixing with reduced glutathione injection and vitamin K1 injection in 5 % glucose injection and 5 % xylitol injection .

第7天甘草酸二铵组APACHEⅢ评分、MODS评分均较治疗前降低（P0.05），而对照组APACHEⅢ评分、MODS评分则降低不明显（P0.05）；

The APACHE ⅲ scores and MODS scores of diammonium glycyrrhizinate group decreased more obviously at 7 day than 0 day ( P0.05 ) . The concentration of serum TNF α of two groups decreased .

结论：在综合治疗基础上联用Lipo-PGE1与甘草酸二铵是治疗重型肝炎的有效方法。

CONCLUSIONS : Lipo-PGE 1 in combination with diammonium glycyrrhizinate injection plus the combined therapy is effective for the treatment of severe hepatitis .

结果：甘草酸二铵能对抗异丙肾上腺素所致大鼠急性心肌损伤，使其心电图ST段异常抬高数减少，减少MDA的生成，增加心肌组织SOD的活力，抑制CPK和LDH的释放。

Results : It was showed that DG inhibited the elevation of ST period , reduced significantly myocardial MDA content , increased myocardial SOD activity and depressed the release of CPK and LDH in the isoprenaline-induced damage to the rat heart .

目的：观察新一代甘草酸制剂甘草酸二铵脂质配位体（DGLL）对酒精性脂肪肝的治疗作用。

AIM : To study the therapeutic effect of Diammonium Glycyrrhizinate lipid ligand ( DGLL ) on alcoholic fatty liver .

硫胺素组与甘草酸二铵组比较肝功能复常率明显降低，差异有显著性（P001）。

Normalization rate of liver function in thiamine group is much lower than that in diammonium glycyrrhizinate group , which showed significant difference ( P0.01 ) .

目的：评价甘草酸二铵磷脂复合物注射剂（DG-PC）的对急性、慢性免疫性肝脏损害的保护作用。

Objective : To investigate the protective effects of diammonium glycyrrhizinate phospholipid complex injection ( DG-PC ) on acute and chronic-immunological liver injury .

甘草酸二铵在大耳兔体内的药物代谢动力学研究

Study on pharmacokinetics of Diammonium Glycyrrhizinate in the big ear hare

序贯法研究甘草酸二铵对小鼠镇咳作用

Sequential study on the antitussive effect of diammonium glycyrrhizinate on mice

甘草酸二铵与牛血清白蛋白相互作用的光谱

Spectroscopic Studies on the Interaction between Diammonium Glycyrrhizinate and Bovine Serum Albumin

甘草酸二铵注射液有效期的测定草酸的制备

Determination of expiration date of Diammonium Glycyrrhizinate injection PREPARATION OF OXAlIC ACID

还原型谷胱甘肽甘草酸二铵联合治疗慢性乙型肝炎

Effects of Reduced Glutathione and Glycyrrhizin on Treatment of Chronic Hepatitis B

甘草酸二铵及其磷脂复合物注射液的小鼠体内分布研究

Tissue Distribution of Diammonium Glycyrrhizinate and its Phospholipid Complex Injection in Mice

活性炭对甘草酸二铵磷脂复合物注射液含量的影响

Effects of Activated Carbon on Content of Diammonium Glycyrrhizinate Phospholipid Complex Injection

甘草酸二铵半乳糖化壳寡糖纳米粒的制备及体外释放考察

Preparation and release characteristics of diammonium glycyrrhizinate chitosan galactosyl oligosaccharide nanoparticles in vitro

甘草酸二铵磷脂复合物对急慢性肝损伤保护作用的研究

Protective Effects of Diammonium Glycyrrhizinate Phospholipid Complex on Acute and Chronic Liver Injury

高效液相色谱-质谱法研究甘草酸二铵胶囊在健康人体的药代动力学

Study on the pharmacokinetics of diammonium glycyrrhizinate capsule in healthy volunteers by HPLC-MS

甘草酸二铵对溃疡性结肠炎大鼠作用的实验研究

Effects of Diammonium Glycyrrhizinate on Ulcerative Colitis in Rats

甘草酸二铵对动物静脉血栓形成及凝血时间的影响

Effects of Diammonium Glycyrrhizinate on Thrombus Formation and on Blood Coagulation in Animals

甘草酸二铵对大鼠结肠炎的抗炎作用机制研究

Study on the anti-inflammatory mechanism of diammonium glycyrrhizinate in acetic acid-induced colitis of rats