汗孔

我们研究了播散性浅表光化性汗孔角化症（DSAP）和寻常型鱼鳞病（IV）。

We studied disseminated superficial actinic porokeratosis ( DSAP ) and ichthyosis vulgaris ( IV ) .

播散性浅表性光线性汗孔角化症（Disseminatedsuperficialactinicporokeratosis，DSAP）是一种少见的慢性角化性皮肤病，呈常染色体显性遗传。

Disseminated superficial actinic porokeratosis ( DSAP ) is an uncommon autosomal dominant chronic keratinization disorder .

结论发现了与家系4高度连锁的3个SNPs，排除了60个候选基因是汗孔角化症致病基因的可能性。

Conclusion 60 candidate genes were excluded . 3 SNPs were detected linking to the disease in this family .

目的对播散性浅表光线性汗孔角化病（DSAP）的致病基因进行定位。

Objective To identify the genetic locus for disseminated superficial actinic porokeratosis ( DSAP ) .

骨髓移植后发生Mibelli汗孔角化症

Porokeratosis of Mibelli following bone marrow transplantation

患者女，55岁。1年前左足第2趾出现一约1.5cm×1.2cm大的肿块，组织病理诊断为小汗腺汗孔瘤。

A 55-year-old female had an enlarging mass on her second toe of left foot with the size of 1.5 cm × 1.2 cm for one year . The diagnosis of eccrine poroma was based on the skin biopsy and histopathology .

15例汗孔角化症回顾分析

A Retrospective Study of 15 Patients with Porokeratosis of Mibelli

全身放疗及应用免疫抑制剂后发生多发性汗腺汗孔瘤

Multiple eccrine poromas in the setting of total body irradiation and immunosuppression

五个汗孔角化病家系的临床和遗传特点

Clinical Manifestation and Heredity Feature in Five Pedigrees with Porokeratosis

播散性浅表性光化性汗孔角化症并发鳞状细胞癌1例

A Case of Disseminated Superficial Actinic Porokeratosis combined with Squamous Cell Carcinoma

高分化恶性小汗腺汗孔瘤的局部化疗

Treatment of advanced malignant eccrine poroma with locoregional chemotherapy

报告1例恶性小汗腺汗孔瘤。

A case of malignant eccrine poroma is reported .

14例小汗腺汗孔瘤的临床病理分析

A clinicopathological analysis on 14 cases of eccrine poroma

掌跖及泛发性汗孔角化症一家系报道

The first pedigree report of porokeratosis plantaris , palmaris , et disseminata in China

浅表播散型汗孔角化症致病基因的定位克隆

Disease Gene Positional Cloning of Disseminated Superficial Porokeratosis

阴囊汗孔角化症误诊为湿疹1例

A Cases of Scrotum Porokeratosis Misdiagnosed as Eczema

疣状增生性汗孔角化症1例

A case of porokeratosis with verruciform hyperplasia

汗孔汗腺瘤的组织病理学与免疫组织化学研究

Histopathological and immunohistochemical studies of poroid hidradenoma

显著角化过度型汗孔角化症1例

Obvious hyperkeratosis porokeratosis : a case report

播散性浅表汗孔角化病的基因定位

Gene Mapping of Disseminated Superficial Porokeratosis

结果汗孔角化症病因不明确。

Results The etiology is uncertain .

同时排除了这一区域中60个候选基因是汗孔角化症致病基因的可能性，为以后汗孔角化症致病基因的研究节省了大量的人力物力。

And 60 candidate genes were excluded that will give an insight into the pathogenesis of DSP .

结论遗传、环境和免疫因素可能在汗孔角化症发病中起重要作用；

Conclusions Genetic , environmental and immunizing factors play significant roles in the invasion of porokeratosis of Mibelli .

我们报道一例40岁男性发生在臀部的小汗腺汗孔瘤。

We reported one case of eccrine poroma , which was located on the hip of a40-year-old man .

乳突纹线上的汗孔在现场纹线特别少的情况下，也可以进行人身识别。

Under the circumstances of fewer prints , sweat pores on papillary ridge can also launch personal identification .

汗孔瘤是发生于皮肤的良性附属器肿瘤，中年人多见，无性别倾向。

Eccrine poroma is a benign adnexal skin tumor seen in middle aged individuals with no sex predilection .

其它因素如器官移植、免疫抑制剂治疗、阳光照射、外伤、感染因素等能诱发汗孔角化症。

Such as transplantation , immunosuppressive therapy , sunlight exposure , trauma and infective agents , it can induce porokeratosis .

小汗腺汗孔瘤、增殖性外毛根鞘囊肿和毛囊孔上皮瘤标本中多在鲍温病样组织变化的区域内见稀疏阳性表达的肿瘤细胞。

Sparse positive staining was observed within the areas showing bowenoid change in eccrine poroma , proliferating trichilemmal cyst and trichoepithelioma .

对一个弥漫性浅表性光敏性汗孔角化症家系致病基因的定位和对迟发型2型糖尿病易感基因的研究

Mapping the Disease Gene in a Disseminated Superficial Actinic Porokeratosis Family and Study Susceptibility Genes of Late-onset Type 2 Diabetes Mellitus

结果：发现汗孔瘤是一种特异性的肿瘤类型：（1）肿瘤发生于表皮，部分累及真皮。

Results Eccrine poroma was a specific tumor : ( 1 ) Originate from the epidermal , some involve the dermal .