氯贝丁酯

目的研究氯贝丁酯对离体小鼠肝线粒体和体外培养的AML-12肝细胞损伤的作用机制。

Objective To explore the effect of clofibrate on freshly isolated mouse liver mitochondria and a cultured hepatocyte cell line , AML-12 .

苯巴比妥及氯贝丁酯对小鼠体内梭曼解毒作用的影响

Effects of phenobarbital and clofibrate on the detoxification of soman in mice

用氯贝丁酯处理过的肝细胞及线粒体内自由基显著增加。

Treatment of hepatocytes with clofibrate caused a significant increase in intracellular and mitochondrial ROS .

考察了肝微粒体酶诱导剂苯巴比妥及氯贝丁酯对小鼠体内解毒酶的诱导作用及对小鼠体内梭曼解毒作用的影响。

The induction of phenobarbital and clofibrate , which are liver microsomal inducers , on organophosphate detoxifying enzymes , and the effect of these two medicines on the disappearance of soman from blood in mice were investigated .