核受体

ERβ属于核受体超家族成员。

ER β is a member of the nuclear receptor super family .

结合了CPA的AR可与核受体协同抑制因子作用。

CPA-bound AR associates with nuclear receptor corepressors .

结果孕激素受体及B亚型均为核受体。

Results PR and PR B were nuclei receptors .

短回文序列具有核受体的DNA结合域，调节核受体的表达。

Short palindrome repeats are characteristic of DNA-binding domain of nuclear receptors .

前列腺素E核受体介导的信号转导途径与膜受体介导的信号途径不同，对于基因转录的调控机制也不同。

They are different in the signaling pathways and in regulation mechanism between nuclear receptors and membrane receptors .

PR（progesteronereceptor），是核受体家族中的重要转录因子。

HPR ( human progesterone receptor ), which is the important nucleus transcriptional factor .

雌激素受体（ER）包括α和β等2种，均为核受体。

Estrogen receptors ( ER ), which belong to nuclear receptor , include ER α and ER β .

雌激素受体β（ERβ）属于核受体超家族成员，是一类配体调节的转录因子。

Estrogen receptor β( ER β) is a ligand-regulated transcriptional factor , which belongs to the nuclear receptor superfamily .

GCNF（GermCellNuclearFactor）属于核受体超家族成员，是一个孤儿受体。

GCNF ( Germ Cell Nuclear Factor ) is a member of nuclear receptor superfamily and also an orphan receptor .

背景肝X受体是一种核受体，与细胞内胆固醇及糖等能量代谢有关。

Background Liver X receptors ( LXRs ) are members of the nuclear hormone receptor superfamily which involve in energy metabolism of intracellular cholesterol and glucose regulation .

核受体激动剂对人卵巢颗粒细胞和乳腺癌MCF-7细胞芳香化酶的调节作用

Nuclear receptor agonist regulating aromatase activity in human ovarian granulosa and breast cancer MCF-7 cells

PR在神经细胞核中的定位表明其为核受体，很有可能在基因水平上参与拟穴青蟹视神经节的生理活动调节。

PR is a nuclear receptor which may mediate the physiological activities of optic ganglia via nuclear receptor in gene level .

核受体组成一个蛋白质大家族，它们作为配体调节的转录因子，能够直接与DNA结合，调节下游靶基因的表达。

The nuclear receptors constitute a large family of proteins and can be considered as ligand-inducible transcription factors , which can bind directly to DNA and regulate expression of downstream target genes .

目的了解维甲酸核受体（RAR－α）在肝细胞癌（HCC）的表达分布和它的临床意义。

Objective The distribution of retinoic acid receptor ( RAR α) expression in hepatocellular carcinoma ( HCC ) and its clinical significance were studied .

目的实施大鼠穹窿切断术研究海马神经元核受体GR（GlucocorticoidReceptor糖皮质激素受体）表达的变化。

Objective To investigate the expression of the glucocorticoid receptor which is one of neuclear receptors , in the hippocampal neurons after fornix transection .

DCC法检测食管鳞癌组织中雌、孕激素胞浆、胞核受体

Estrogen and Progesterone Receptor in Cytosols and Nuclei of Esophageal Squamous Carcinoma Tissues by DCC Method

肌钙蛋白I2作为核受体辅活化子的鉴定

Identification of Troponin I 2 As a Nuclear Receptor Coactivator

核受体辅助抑制因子中ETO结合结构域的确定

Determination of ETO interaction domain within nuclear receptor co-repressor

维甲酸核受体RARα真核表达载体的构建、突变纠正及表达

Construction , point mutation correction and expression of eukaryotic expression vectors for retinoic acid nuclear receptor

论文的主要内容包括：（1）利用杆状病毒表达系统表达全长核受体PPARγ。

The principal contents of this thesis including : ( 1 ) expression of the full-length PPAR γ by BEVS .

肌钙蛋白I2辅助活化多种核受体的反式作用

Troponin I 2 Co-activating Transactivation of Multiple Nuclear Receptors

作为核受体家族的成员之一，AR在结合了雄激素后，转位到核内，与靶基因启动子结合，发挥转录因子的活性。

Similar to other nuclear receptors , upon binding to androgen , AR is translocated into nucleus , binds to the promoters , and mediates transcription of target genes .

雌激素的活性主要是受雌激素受体（ER）的调节，雌激素受体是核受体家族中的一员，并且作为配体激活型转录因子调节雌激素应答基因的表达水平。

Estrogen action is mediated by estrogen receptors ( ERs ), members of the nuclear receptor family and ligand-activated transcription factors that control the expression of estrogen - responsive genes .

17β-雌二醇调控子宫内膜癌细胞孤儿核受体ERRα表达的研究

Regulatory Effect of 17 β - Estradiol on Expression of Orphan Nuclear Receptor ERR α in Endometrial Carcinoma Cell Lines

目的：探讨孤儿核受体-雌激素受体相关受体（ERR）α及雌激素受体（ER）α在子宫内膜癌发生、发展中的作用以及临床应用价值。

Objective : To explore the roles of estrogen receptor-related receptor ( ERR ) α and estrogen receptor α in endometrial carcinoma and their clinical values .

孕酮受体（progesteronereceptorPR）基因是核受体超家族成员之一，在介导与调节卵巢排卵、胚胎植入、乳腺发育等生殖生理以及相关生殖健康中起着关键的作用。

Progesterone receptor ( PR ) is a member of nucleolus-receptor superfamily . PR exert important roles for ovulation , embryo implantation , mammary gland development : and other reproductive process .

过氧化物酶增殖物激活受体γ2（PPARγ2）是一个转录因子，属于核受体超家族的成员之一。

Peroxisome proliferator-actived receptor γ 2 ( PPAR γ 2 ) is a translation factor that belongs to the superfamily of nuclear receptors .

维生素D3、9-顺式维甲酸及其相应核受体对hsp90β基因表达的调控

The Regulation of Vitamin D_3 and 9-cis-retinoic Acid and Their Receptors on Human hsp90 β Gene

核受体LXR与炎症反应在鼠原代脑星形细胞间的相互影响

The interaction of nuclear receptor LXR and inflammation in mouse brain primary astrocytes

BMP能诱导成骨细胞和软骨细胞的分化成熟，作为下游基因，受到核受体的支配，当受到核受体信号后，并能在体内诱导异位成骨。

As a downstream gene , dominated by the nuclear receptor , when the signal by the nuclear receptor , cartilage cells and could induce ectopy osteoblast .