核苷酸切除修复

针对不同的DNA损伤。细胞内有许多不同的修复方式对其进行修复，包括碱基切除修复、核苷酸切除修复、错配修复、同源重组修复等。

There are many DNA repair pathways to different DNA lesions , including base excision repair , nucleotide excision repair , mismatch repair and homologous recombination repair .

在DNA损伤的众多修复途径中，核苷酸切除修复（NER）途径能广谱识别大多数严重损伤造成的DNA螺旋扭曲，是DNA损伤的主要修复系统，也是机体抵抗致癌效应的主要防御机制。

Nucleotide excision repair ( NER ) can recognize a broad spectrum of helix-distorting lesions and is a major repair system of DNA damage .

在恢复阶段的早期5天内，DNA损伤持续的增加，这应该是由于对DNA损伤的修复造成的，例如，碱基切除修复或者核苷酸切除修复。

At the first five days of the recovery period , the increased DNA damage may be due to the repair of DNA damage , such as base or nucleotide excision repair .

背景与目的：XPC基因参与核苷酸切除修复，该基因存在单核苷酸多态性（SNP）位点，并可能通过SNP位点碱基的改变影响其修复能力及疾病易感性。

BACKGROUND & OBJECTIVE : Xeroderma pigmentosum group C ( XPC ) gene is involved in nucleotide excision repair ( NER ) .

核苷酸切除修复基因和谷胱甘肽-S-转移酶基因多态与胆道癌风险关系的研究

Relationship between polymorphisms of DNA repair genes and glutathione-S-transferase genes and risk of biliary tract cancer