排异反应
- 名rejection reaction;transplant rejection
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在基础研究中则可用于T细胞与B细胞分化、活化机制、抗原递呈、协同刺激机制、免疫耐受、移植排异反应和自体免疫等的研究。
In fundamental study , they can be used in research on T , B differentiation and activation , antigen presentation , co-stimulating mechanism , immune tolerance , transplantation rejection and auto-immune .
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IL-2R在急性细胞性排异反应的同种异体尸体移植肾组织中的检测及意义
Predictive value of IL 2R in renal tissue during acute renal allograft rejection
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壳聚糖(chitosan,CS)是一种天然的聚阳离子多糖,具有无毒、生物可降解、不会引起排异反应等特点。
Chitosan is a kind of natural gather cationic biological polysaccharide . It is biodegradable and non-toxic .
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抗CD25单克隆抗体预防肾移植术后急性排异反应的研究
Evaluation of anti-CD25 monoclonal antibody to prevent acute rejection after renal transplantation
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CsA玻璃体腔中注射能抑制异种RPE移植的排异反应但易引起明显的视网膜毒性反应。
Intravitreal CsA delays rejection of RPE xenografts in rabbits but causes marked retinal toxicity .
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被同种异体抗原致敏的受者小鼠,对有关供者混合淋巴细胞反应(mixedlymphocytereaction,简称MLR)和移植皮片再次排异反应,都显示反应得到加速和增强。
Accelerated and enhanced mixed lymphocyte reaction ( MLR ) and skin allograft rejection ( SAR ) were observed in mice sensitized with related alloantigens .
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结论CDFI监测移植肾后的排异反应快速,准确无创,可早期发现病情变化并指导治疗。
Conclusion CDFI is a fast , accurate and non-invasive technique in evaluating renal transplant rejection early .
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大鼠皮肤移植后ICAM-1和LFA-1与排异反应的关系
Relations Between Rejection and ICAM-1 , LFA-1 after Skin Transplantation in Burned Rats
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术后早、后期排异反应发生率及中、后期毒性反应的发生率均有显著性差异(P<0.05)。
Significant differences were found at the rate of exclusive reaction between the early and late POSs , and also at the rate of poisoning reaction between the middle and late POSs ( P < 0.05 ) .
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结论CDFI是了解移植肾排异反应的重要方法。
Conclusion Color Doppler Blood Flow Image ( CDFI ) is a important method to know kidney transplant reaction of rejection .
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198份血样测定结果统计分析表明,术后排异反应组与无排异反应组之间给药剂量及环孢素A血浓度存在显著性差异(P<0.05),男女患者排异反应发生率有较大区别。
The demographic results of 198 determined samples appeared that dosages and cyclosporine blood levels had significant difference between rejection and unrejection ( P < 0.05 ), and the incidence of rejection had more difference between male and female .
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目的探讨应用超谐波声学造影和声学密度定量(AD)技术,定量评价异体移植肾急性排异反应时皮质血流灌注的价值。
Objective To evaluate the value of using ultraharmonic contrast imaging ( UHCI ) and acoustic densitometry ( AD ) technique to quantify cortex blood perfusion of acute rejection in renal allograft .
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~(99m)Tc-DTPA肾动态显像对移植肾排异反应的监测价值
The value of ~ ( 99m ) tc-dtpa kidney dynamic imaging in monitoring rejection of renal allografts
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1例OKT3逆转肾移植术后急性排异反应的护理
Nursing care of a case with acute rejection after kidney transplantation reversed by OKT_3
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磷酸三钙(TCP)与正常骨组织的钙磷比很接近,具有较好的生物相容性,与骨结合性好,无排异反应。
Tricalcium phosphates ( TCP ) have also similar Ca / P ratio to that of normal bone mineral , and good biocompatibility and great ability to chemically bond with bone tissue and no rejective reaction .
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低血药浓度FK506在肝移植抗排异反应中的应用碱化利多卡因在剖腹产中母婴血药浓度的研究
To discuss the immunosuppressive treatment of low blood concentration in FK506 The Study of Alkalized Lidocaine Serum Concentration in Mothers and Their Infants in Caesarean Section
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结果在移植后,移植心脏的排异反应和凝血逐渐加重,豚鼠组织因子mRNA表达强度逐渐减弱,大鼠组织因子mRNA表达强度逐渐增强。
Results During the period of post-transplantation , the blood coagulation in the cardiac graft became more and more serious . The expression of guinea pig tissue factor mRNA decreased while the expression of SD rat tissue factor mRNA increased .
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急性排异反应时的细胞免疫过程中,CD4+T细胞首先被活化,继而释放IL-2等细胞因子,然后使CD8+T细胞增殖分化为效应细胞。
In cell immumity process of acute rejection , CD4 + T-cell was activationed first and delivery IL-2 cell factor and so on , then CD8 + T-cell multiplicated and differentiated to effector cell .
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目的应用常规超声和多普勒组织成像(Dopplertissueimaging,DTI)技术观察心脏移植术后的排异反应,并与病理检查对照,探讨超声检查在观察心脏移植术后排异反应的价值。
Objective We observed the rejection reaction after heart transplantation by general echocardiography and Doppler tissue imaging ( DTI ), by comparison with pathological examination , in order to discuss the value of echocardiography observing rejection reaction after heart transplantation .
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提示:动态检测SIL-2R水平变化对异体移植术后早期急性排异反应具有早期、灵敏,较为特异的诊断价值。
It is our conclusion that dynamic examination of SIL-2R in serum is a sensitive , specific , and practical method in diagnosis of early acute rejection on allograft recipients .
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结论FK506和Res都可以通过抑制CD4+T淋巴细胞增殖而阻止或延缓同种异体心脏移植的急性排异反应。FK506与Res联用具有协同作用,可更有效地产生免疫抑制作用。
[ Conclusion ] Both FK506 and resveratrol can suppress proliferation of CD4 + T-cell and expression level of IL-2 , so they can prevent or delay acute rejection .
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虽然造血干细胞移植是根治AML的方法,但是存在着排异反应、治疗费用昂贵等诸多问题。
Transplantation of hemopoietic stem cell is a radical cure of AML , But there are still many problems have to be solved such as immune reaction and high cost treatment .
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RT术后早期排异反应发生率较后期明显,而早、后期的中毒反应发生率均较中期明显升高。
The rate of exclusive reaction is much higher in early POS than in late POS , while the rate of poisoning reaction is much higher in the early and late POSs than in middle POS.
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结果3例患者均顺利出院,心功能恢复至Ⅰ-Ⅱ级(NYHA),围术期无感染或严重排异反应发生。
Results Three patients were well recovered and discharged without acute rejection or infection , heart function recovered to class ⅰ - ⅱ( NYHA ) .
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观察供受体血型不合肝移植中C4d沉积的特点,探讨移植肝体液排异反应的诊断标准。
To observe the expression features of C4d in ABO-incompatible liver transplantation and investigate the diagnostic criteria in humoral rejection of liver transplantation .
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IgG等免疫球蛋白在肝窦内皮细胞上弥漫强阳性沉积,并伴有C4d等补体成分表达,可作为移植肝组织中存在体液排异反应的证据。
It may be regard as the evidence of humoral rejection in transplant hepatic tissue that immunoglobulins IgG accompany with C4d and other complements diffusely deposited in hepatic sinusoidal endothelial cells .
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结论CDFI结合CDPI对诊断移植肾排异反应很有价值,阻力指数(RI)是一项评定排异反应的重要指标。
Conclusion CDFI combined with CDPI has valuable clinical significance for diagnosing rejection in transplanted kidneys , and resistance index ( RI ) is very important in accessing rejection .
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目的:建立一种适用于肿瘤药敏人癌肾包膜下移植法(SRCA)的免疫抑制小鼠模型,克服普通小鼠的免疫排异反应及裸鼠费用昂贵的缺陷。
Objective : To eliminate the rejective reaction of host-versus-graft in the SRCA , a new kind of immunosuppressed mice model was established .
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ADAP缺失联合共刺激通道阻断对有效抑制小肠移植物的排异反应有协同作用。
There was a synergistic effect of MR-1 therapy and ADAP deficiency in inhibiting the rejection of small bowel allograft . 4 .
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移植肾慢性排异反应:肾体积明显增大,皮质回声强,CDE显示肾内血流进一步减少,肾动脉血流速在收缩期和舒张期均减低,RI、PI增高,与对照组相差显著(P<0.001)。
In chronic rejection cases , the renal artery was lack of blood flow both during diastole and systole . The RI and PI of the main renal artery were higher compared to the control ( P < 0 001 ) .