抗凝血

抗凝血因子蛋白C系统的生理及应用前景

The Physiological Characters and Prospect of Anticoagulant Factors in Protein C System

活性蛋白C（activatedproteinC，APC）是一种内源性蛋白，具有抗凝血、促进纤维溶解、抗炎的功能。

Objective : Activated protein C , an endogenous protein , has function of anticoagulant , promoting fibrinolysis and ant-inflammation .

具有抗凝血、降血脂、抗肿瘤和抗HIV的作用。

It has anti-clotting , blood fat , anti-tumor and anti-HIV effects .

活化蛋白C抵抗对老年人凝血、抗凝血系统指标的影响

Influences of the activated protein C resistance on the function of coagulation and anticoagulation in the elderly with thrombotic diseases

改性后PET材料的表面亲水性和抗凝血性能得到很大改善。

After the treatment , the hydrophilicity and anticoagulative property of PET was greatly improved .

pH值和金属离子对尖吻蝮蛇抗凝血因子Ⅱ二级结构的影响

The Effects of pH and Metal Ions on the Secondary Structure of Anticogulation Factor ⅱ Studed by CD Spectroscopy

在排除多种因素并查阅了相关资料后，推测有可能是抗凝血中抗凝剂的使用对基因组DNA的扩增效率产生影响。

Referring to involved information and after excluding many factors , we speculated that anticoagulant in blood may impact PCR amplification efficiency .

结论PⅢ表面改性的支架具有良好的抗凝血性能，术后血栓形成率较未改性支架有明显降低。

Conclusion Stent with surface modification has anticoagulant performance that the formation rate of thrombus after operation declined explicitly in contrast to the figure without surface modified stent .

使用EDTA抗凝血检测凝血酶原时间

Use of EDTA Samples for Prothrombin time Measurement

6次随访共收回调查问卷427份，采集EDTA抗凝血427份。

427 questionnaires with EDTA-anticoagulant venous blood were collected during the six times of follow-up .

尖吻蝮蛇毒内一种新抗凝血因子ACFII的纯化及特性

Purification and Characterization of a Novel Anticoagulation Factor ( ACF II ) from the Venom of Agkistrodon acutus

[方法]采集EDTA抗凝血并置于室温条件下保存。

[ Methods ] EDTA - anticoagulant peripheral blood were collected and stored at ambient temperature .

动物实验证明，细菌产生的PLC具有抗凝血及延缓血小板聚集的作用，可预防血栓形成和心脑血管疾病。

Many animal investigations showed that PLC can significantly inhibit platelet aggregation and adhesion , and can prevent coming into thrombus and cardiovascular and cerebrovascular disease .

制药工业研究公司DecisionResources预测说，如果新药成功的话，抗凝血药市场将从去年的三十亿美元翻一番增加到2016的七十四亿美元。

Drug industry research firm Decision Resources predicts that , if successful , the new drugs could double the size of the anti-coagulant market from $ 3 billion last year to $ 7.4 billion in2016 .

研究发现HL一P抗凝血作用既不依赖户口户一川又不被血小板第4因子抑制，推测HL一P可直接抑制凝血酶。

And the anticoagulative action of HL-P depended on neither AT-III nor PF4 . It may be related to the function of restraining thrombin directly .

纤维素硫酸酯（CS）是一种硫酸酯化多糖衍生物，具有抗凝血等多种生物活性。

Cellulose Sulfate ( CS ) is a sulfated polysaccharide derivative , which shows a variety of biological activities such as anticoagulation etc.

经非猪瘟免疫猪增殖猪瘟病毒石门株，从抗凝血中直接提取病毒RNA进行RT－PCR，获得了猪瘟病毒石门株E2基因片段。

E2 gene of CSFV shimen strain was amplified by RT-PCR method from the blood of infected pig , then cloned and sequenced .

14例健康对照者（对照组），取静脉抗凝血，分离纯化红细胞，分别测定血浆、红细胞牛磺酸浓度，并测定3H标记的牛磺酸跨红细胞膜转运。

Taurine content in plasma and erythrocytes and the kinetics of 3H taurine transport by erythrocyte were measured .

TM在抗凝血过程中发挥着重要作用。TM基因突变或表达减少能促使动脉血栓的形成；而局部TM基因过度表达能避免兔动脉血栓形成。

TM plays a key role in anticoagulation , and mutation or down-regulation of TM promotes while overexpression of TM prevents arterial thrombosis .

去年，FDA就增加了一项关于一种抗凝血药物：clopidogre（氯吡格雷）的警告。

For example , last year the FDA added a warning to the prescribing info for the widely used clopidogrel .

类肝素化抗凝血材料的研究&PVA，PET及PEU的磺化反应及血液相容性

Study on Heparin like Materials & Sulfonization and Blood Compatibility of PVA , PET and PEU

埃及伊蚊抗凝血因子Xa基因片段的克隆测序

Part Gene Sequence of Factor Xa-directed Anticoagulant from the Vector Mosquito Aedes aegypti in China

皖南尖吻蝮蛇蛇毒内抗凝血因子（ACF）的二级结构和金属离子对其影响的CD谱研究

CD spectroscopy studies of secondary structure of anticoagulation factor in the venom of Agkistrodon acutus and the effect of metal ions on the structure

本发明包括抗体，该抗体通过以高度亲和力及特异性结合天然人类TF而提供优异抗凝血活性。

The invention includes antibodies that provide superior anti-coagulant activity by binding native human TF with high affinity and specificity .

第二部分的研究内容：研究了尖吻蝮蛇蛇毒中抗凝血因子II（ACFII）的降血压作用。

The second part is about the exploration of the hypotensive mechanism of anticoagulation factor II ( ACF II ), isolated from the venom of Agkistrodon acutus .

利用动态凝血实验和血小板粘附实验研究了CDP的抗凝血性能。

The antithrombogenic properties of CDP were studied by kinetic clotting experiment and platelet adhesion experiment .

文中提及的金属离子对ACF的抗凝血活性没有显著的影响。

All the metal ions mentioned in this paper do not give intensive effect on the anticoagulation activity of ACF .

系统研究了在医用316L不锈钢中加入0.05%La后的体外抗凝血性能.结果表明。

The in vitro anticoagulant property of a medical grade 316L stainless steel with 0.05 % La addition was systematically studied .

微量PCRSSP法仅需1ml抗凝血，耗时约2h，而且分辨率高。

The micro SSP PCR technique needed only 1 ml anticoagulant blood samples spent 2 hours approximately , and had a higher resolution .

SPK提取液在体外有明显的抗凝血和直接溶解血凝块的作用。

The SPK extract solution holds obvious effects of anticoagulation and thrombolysis in vitro .