平阳

平阳霉素与Fe~（2+）反应产生·OH的自旋共振研究

ESR Study on the Production of Hydroxyl Radical by Pingyangmycin and Ferrous Iron

梯度洗脱HPLC法测定盐酸平阳霉素及注射药物中的有关物质

Determination of related substances in bleomycin A5 hydrochloride by gradient elution HPLC

HPLC法测定磁性微球及大鼠肝组织中的平阳霉素

Determination of Pingyangmycin in Magnetic-Microspheres and Rat Liver by HPLC

平阳霉素后处理提高EMS诱变的遗传学效应

Increase of Genetic Effect of EMS Mutation through Posttreatment by PYM

平阳霉素与Mn~（2＋）络合物结构的~1H－NMR弛豫研究

Structural study on the proton relaxation of Mn ￣( 2 + ) - pingyangmycin complex

平阳霉素诱发大鼠白内障机理的ESR研究

ESR Study of the Mechanism for Induced Cataract by Pingyangmycin

平阳霉素；PVA颗粒；贫血，珠蛋白生成障碍性；婴幼儿。

Pingyangmycin ; PVA granules ; Anemia , Disorder of globin generation ; Infant .

方法采用平阳霉素行疣体基底部注射，并联合α－2α干扰素全身用药治疗特殊部位CA。

Methods Patients with CA were treated with bleomycin by local injection and combined with general administration of a - 2a interferon .

平阳霉素（博菜霉素A5）对同步化的CHO细胞的敏感周期时相的研究

Cell cycle phase sensitivity of CHO cell to Pingyangmycin

~（99m）Tc-平阳霉素肺显像诊断原发性肺癌

~ ( 99m ) Tc-Pingyangmycin imaging in the diagnosis of primary lung cancer

平阳霉素与单克隆抗体Fab′片段偶联物的抗肿瘤作用

Antitumor effects of Pingyangmycin conjugated with Fab ′ fragment of monoclonal antibody

而抗癌药物平阳霉素对各时相细胞都有较强毒性，特别是对G2M期细胞，杀伤作用特别强。

The cytotoxicity of antitumor drug pingyangmycin to the synchronized cells was higher , especially to the G_2M phase cells .

平阳霉素对HeLa细胞的大分子生物合成及超微结构的影响

Effects of Pingyangmycin ( bleomycin a_5 ) on the macromolecular biosynthesis and ultrastructure of HeLa cells

平阳霉素乳剂对增殖期毛细血管瘤组织中VEGF和bFGF的影响

The research on the effect of bleomycin-A_5 emulsion on VEGF and bFGF in the tissues of capillary hemangioma in proliferation phase

博来霉素A6和平阳霉素抗大肠癌实验研究

Study on Antitumor Activity of Bleomycin A6 and Pingyangmycin against Colorectal Cancer

目的探讨平阳霉素引发细胞凋亡与分裂原激活的蛋白激酶家族（Mitogenactivatedproteinkinase，MAPK）信号转导通路的关联性。

Objective To study the role of mitogen activated protein kinase ( MAPK ) pathway in the action mechanism of PYM induced KB cell apoptosis .

目的探讨平阳霉素对增殖期毛细血管瘤组织中血管内皮细胞生长因子（VEGF）和碱性纤维母细胞生长因子（bFGF）表达的影响。

Objective To study the effect of bleomycin-A5 on the expression of VEGF and bFGF in the tissues of capillary hemangioma in proliferation phase .

注射平阳霉素后不同时间电镜检查均可见到凋亡细胞；TUNEL标记结果显示凋亡广泛发生于脾窦内皮细胞及其他脾细胞；

TUNEL staining indicated that apoptotic cells existed extensively in endothelial cells of splenic sinus and others splenic cells .

应用平阳霉素与单克隆抗体Fab′片段偶联物抑制肝癌生长与肿瘤肝转移

Inhibition of the growth of hepatoma and hepatic metastasis by pingyangmycin conjugated with Fab ′ fragment of monoclonal antibody

PDT联合局部化疗组除PDT治疗外，于每次激光照射前肿瘤局部注射化疗药物5-FU或平阳霉素。

In PDT combined with loacl chemotherapy group , 5-Fu or pingyangmycin was locally injected prior to each irradiation .

报道了一种实时监测平阳霉素（BLMA5）氧化切割DNA过程的荧光分析方法。

A novel fluorescence assay for real - time monitoring of DNA cleavage process by bleomycin A5 ( BLM A5 ) was described .

目的探讨抑癌基因PTEN在口腔鳞状细胞癌组织中的定量表达，平阳霉素化疗对该基因表达的作用。

Objective To study the quantitative expression of anti-oncogene PTEN in oral squamous cell carcinoma and effect of pingyangmycin on expression of PTEN .

分别通过光学显微镜、扫描电镜和原子力显微镜（Atomicforcemicroscope，AFM）对平阳霉素原位凝胶的结构进行观察，对平阳霉素原位凝胶形成及药物释放的机理进行了深入的探讨。

According to the result of light microscope , SEM and atomic force microscope ( AFM ), the mechanism of gel formation and drug release for PYM in situ gel was further discussed .

CM－1－药物（平阳霉素；PYM）偶联物对裸鼠移植乳腺癌生长的抑瘤率为95%，而同等剂量的游离药物为58%。

The inhibitory effect on growth of breast cancer xenograft in nude mice was 95 % for CM-1-PYM conjugate and 58 % for free drug .

观察平阳霉素碘油乳剂（PLE）栓塞犬甲状腺动脉的效果。

The potency and safety of thyroid artery embolization by Pingyangmycin Lipiodol Emulsion ( PLE ) were observed .

本文报道了抗癌新药&一平阳霉素（PYM）后处理提高甲基磺酸乙酯（EMS）的诱变效果。

Increase of the mutation effect induced by EMS ( ethyl metilsulfate ) through post treatment by PYM was reported in this paper .

目的：评价平阳霉素碘化油乳剂合用PVA微粒肝动脉双重栓塞治疗合并有门静脉短路的肝海绵状血管瘤的可行性和临床疗效。

Objective : To investigate the therapeutic effects of pingyangmycin-lipiodol emulsion ( PLE ) and PVA particles embolization to treat carvernous hemangioma of liver ( CHL ) with A-V shunt .

A组行靶肺支气管肺泡灌注平阳霉素-碘化油乳剂（PLE）及封堵器堵塞靶支气管，B组为对照组。

Group A : pingyangmycin-lipiodol-emulsion ( PLE ) was injected to the target lung , and the target bronchia was obstructed with broncho-occluder by catheter . Group B was normal group .

肿瘤坏死因子和（或）平阳霉素对人食管癌细胞株（Eca-109）体内杀伤作用

Cytotoxic Effect of rh-TNF α and / or Pingyangmycin on Human Esophageal Cancer Cell Line Eca-109 in Vivo

存活生长39例（92.5%），其中32例完成了平阳霉素，卡氮芥（BCNU）、长春新碱（VCR）各浓度的药敏测定。

39 cases ( 92.5 % ) survived , and the chemosensitivity assay was done in 32 cases ( 74.4 % ) .