少精症

FSH、LH、T均呈降低者，无精症组14.3%，重度少精症组7.7%；

The rates of which showed FSH , LH and T reducing together were 14.3 % in azoospermia and 7.7 % in severe oligospermia ;

FSH、LH升高而T在正常参考范围者，无精症组38.1%，重度少精症组23.1%；

The rates of which showed FSH , LH increasing but T in the normal reference range were 38.1 % in azoospermia and 23.1 % in severe oligospermia ;

【目的】建立一套Y染色体微缺失的多重PCR筛查方法，对因无精症或少精症欲行单精子卵细胞浆注射（ICSI）治疗的男性不育患者进行Y染色体微缺失的常规筛查。

To develop a multiplex PCR protocol , suitable for routine screening of microdeletions on the Y chromosome in male infertility patients undergoing intracytoplasmic sperm injection ( ICSI ) .

安徽省少精症患者血液、精子基因组AZF微缺失的检测分析

Analysis of the microdeletion of AZF gene in blood and semen of infertile males with oligozoospermia in Anhui

结论Y染色体AZF微缺失是不明原因无精症、少精症的主要原因之一。

Conclusion Micro-deletion in AZF gene of Y chromosome is one of the major risks for oligospermatism and azoospermatism .

目的：研究男性原发性无精及严重少精症患者Y染色体AZF微缺失区域与临床表型的关系。

The analysis of correlation between karyotype and AZF microdeletion on Y chromosome for patients with azoospermia and severe oligozoospermia .

方法对62例无精症、少精症患者及20例正常男性采用多重聚合酶链反应法进行AZF区基因微缺失检测。

Methods PCR method was used to detect micro-deletion in AZF gene in62 oligospermatism and azoospermatism patients and20 normal male controls .

无精症及严重少精症患者Y染色体AZF微缺失区域与临床表型关系的研究

Study on the Relationship between the Region of Y Chromosome AZF Microdeletion and Clinical Phenotype in Patients with Idiopathic Azoospermia and Oligospermia

目的分析原发无精症和严重少精症患者Y染色体无精症因子C区（azoospermiafactorC，AZFc）DAZ基因（deleted-in-azoospermia，DAZ）部分拷贝缺失的类型与频率。

Objective To analyze the pattern and prevalence of partial copy deletion of deleted-in-azoospermia ( DAZ ) gene in the azoospermia factor C ( AZFc ) region of patients with idiopathic azoospermia or severe oligozoospermia .

方法运用STSPCR法对25例无精症和27例严重少精症患者的Y染色体interval6的23个序列标签位点（STS）进行缺失筛查。

Methods Deletions in 25 azoospermic and 27 severe oligozoospermic Chinese patients were screened by STS PCR strategy . A total of 23 STSs in interval 6 of Yq , including 4 STSs in the deleted azoospermia gene ( DAZ ) region were analyzed .

实验组与对照组DAZ1/DAZ2共缺失率差异有极显著性。结论原发无精和严重少精症存在较高频率的AZFc区DAZ基因的部分缺失，这可能是中国男性原发不育的病因之一。

Conclusion The frequency of partial copy deletion of DAZ gene in Chinese idiopathic azoospermia or severe oligozoospermia patients is much higher than that of fertile controls , suggesting that the deletion of DAZ1 / DAZ2 may be one of the important genetic etiological factors of spermatogenesis damage .

它莫西芬治疗特发性少精症70例分析

Idiopathic oligospermia treated with Tamoxifen : report of 70 cases analysis

无精、严重少精症患者细胞遗传学和Y染色体微缺失研究

Cytogenetic and Y Chromosome Microdeletions in Patients with Azoospermia and Severe Oligozoospermia

少精症患者雄激素受体的临床实验研究

A clinical study of oligospermia patients ' androgen receptor

生精汤治疗少精症、弱精症90例临床观察

Clinical observation of 90 cases Spermatacrasia and Asthenospermia patients treated with Seminiferous soup

SY1191-b2/b3-DAZ3/DAZ4在正常生精组、原发性少精症组和原发性无精症组中的缺失率分别为6.3%、2.4%和1.9%。

6.3 % , 2.4 % and 1.9 % in novel azoospermic group respectively .

特发性无精症和严重少精症患者Y染色体微缺失的分子检测

Molecular Detection of Y Chromosome for the Patients with Idiopathic Azoospermia and Severe Oligozoospermia

口服雄烯二酮导致阳痿及严重少精症

Oral androstenedione-induced impotence and severe oligospermia

雄激素受体基因突变与无精症、少精症关系的临床研究

Clinical Study on the Relationship between Gene Mutation of Androgen Receptor and Azoospermia as well as Oligozoospermia

250例无精症少精症患者睾丸的生殖病理学观察及临床病因病理诊断

The reproductive pathological observation on the testes of 250 cases azoospermia and oligospermia and their clinical aetiological diagnosis

方法应用细胞遗传学和多重聚合酶链反应技术，对148例无精症、严重少精症患者进行检测。

Methods Cytogenetic analysis and multiplex polymerase chain reaction ( PCR ) analysis were done on the 148 patients with azoospermia and serious oligozoospermia .

研究显示：特发性无精症与少精症患者，除睾丸生精功能障碍外，还存在间质细胞功能的损害。

It is suggested that there exist impairment in the function of Leydig cells in addition to functional obstacle of spermatogenesis in men with idiopathic oligozoospermia and azoospermia .

目的研究特发性无精症和严重少精症患者与Y染色体微缺失或突变的关系，建立无精症和严重少精症患者Y染色体微缺失的分子检测方法。

Objectives To evaluate the relationship between microdeletion or mutation on the Y chromosome and Chinese patients with idiopathic azoospermia and severe oligozoospermia and to establish a molecular detection method .

目的探讨无精、少精及严重少精症与染色体核型异常和Y染色体无精子因子（AZF）微缺失的关系。

Objective To investigate the relationship between chromosome abnormalities and Y chromosome microdeletion of azoospermia factor ( AZF ) in patients with azoospermia and oligozoospermia .

考虑到小鼠TEX11基因的缺失可以导致少精或者无精症，TEX11基因的缺失可能是导致男性不育症的遗传因素。

Given that disruption of TEX11 causes azoospermia , or non-measurable sperm levels in mice , mutations in the human TEX11 gene may be a genetic cause of infertility in men .

错配修复蛋白基因多态性与少精、无精症的相关性研究

Association of Mismatch Repair Protein Gene Polymorphism with Oligospermia and Azoospermia

69例少精、无精症患者血清性激素水平分析

Analysis of serum sex hormone in 69 patients with oligospermia and azoospermia

少精及无精症病人生活方式的干预研究特发性无精子症和严重少精子症患者Y染色体基因微缺失研究

Intervention study on the life style of patients with oligospermia or azoospermia

目的探讨少精、无精症患者血清性激素检测的临床应用价值。

Objective To investigate the clinical value of the determinations of serum sex hormone in the patients with oligospermia and azoospermia .