无精症

46，XY，r（21）伴无精症的细胞遗传学分析

An cytogenetic analysis of 46 , XY , r ( 21 ) complicated with azoospermia

结论AZF微缺失导致男性非梗阻性无精症的重要原因之一。

Conclusion AZF microdeletion is one of the important cause of nonobstructive azoospermia .

无精症患者Y染色体微缺失的多重PCR筛查

Multiplex PCR for screening of microdeletions on the Y chromosome in azoospermic patients

方法运用染色体G显带方法，对415例原发无精症或严重寡精症患者的核型进行分析。

Methods Karyotypes were analyzed by chromosome G-banding in 415 infertile patients with idiopathic azoospermia or severe oligozoospermia .

PA患者与VC合并无精症患者的阴囊温度无显著差异。

The Ts of PA patients did not significantly differ from that of VC patients with azoospermia .

无精症睾丸病理与血清FSH水平的关系及对不育诊治的意义

Relationship between testicular biopsy and serum FSH in azoospermia

结论ICSI技术是治疗重度少、弱、畸精症及阻塞性无精症性不育的有效手段。

Conclusion ICSI is an effective treatment for infertility of severe oligo-astheno-teratospermia and obstructive azoospermia .

方法采用外周血染色体G显带、C显带技术和多重聚合酶链反应技术，对2例无精症患者进行了细胞遗传学和分子遗传学检测。

Methods Peripheral blood samples were taken from two patients with azoospermia , and then were examined by use of G banding , C banding cytogenetic analysis and multiplex polymerase chain reaction ( PCR ) microdeletion analysis .

FSH、LH、T均呈降低者，无精症组14.3%，重度少精症组7.7%；

The rates of which showed FSH , LH and T reducing together were 14.3 % in azoospermia and 7.7 % in severe oligospermia ;

方法对22例生育者、44例VC患者及17例原发无精症（PA）患者行远红外阴囊测温。

Methods Bilateral scrotal temperatures ( Ts ) were measured in 22 fertile men , 44 VC patients and 17 primary azoospermia ( PA ) patients by infrared scrotal thermography .

【目的】建立一套Y染色体微缺失的多重PCR筛查方法，对因无精症或少精症欲行单精子卵细胞浆注射（ICSI）治疗的男性不育患者进行Y染色体微缺失的常规筛查。

To develop a multiplex PCR protocol , suitable for routine screening of microdeletions on the Y chromosome in male infertility patients undergoing intracytoplasmic sperm injection ( ICSI ) .

成都地区男性原发性无精症患者Y染色体AZF区域微缺失基因诊断的研究

Study on gene diagnosis of Y chromosome azoospermia factor microdeletions in patients with idiopathic azoospermia in Chengdu

在此条件下分离了Y染色体无精症因子（AZF）区域4个位点的多重聚合酶链反应（PCR）扩增产物。

Under optimal condition , the multiplex polymerase chain reaction ( PCR ) products of four sites of Y chromosome azoospermia factor ( AZF ) were separated .

FSH、LH升高而T在正常参考范围者，无精症组38.1%，重度少精症组23.1%；

The rates of which showed FSH , LH increasing but T in the normal reference range were 38.1 % in azoospermia and 23.1 % in severe oligospermia ;

结论Y染色体AZF微缺失是不明原因无精症、少精症的主要原因之一。

Conclusion Micro-deletion in AZF gene of Y chromosome is one of the major risks for oligospermatism and azoospermatism .

方法对62例无精症、少精症患者及20例正常男性采用多重聚合酶链反应法进行AZF区基因微缺失检测。

Methods PCR method was used to detect micro-deletion in AZF gene in62 oligospermatism and azoospermatism patients and20 normal male controls .

无精症及严重少精症患者Y染色体AZF微缺失区域与临床表型关系的研究

Study on the Relationship between the Region of Y Chromosome AZF Microdeletion and Clinical Phenotype in Patients with Idiopathic Azoospermia and Oligospermia

目的通过遗传物理图谱对Y染色体大片段缺失的断裂位点进行精确的定位，研究Y染色体无精子症因子（azoospermiafactor，AZF）区域微缺失与无精症的关系。

Objective To elucidate the relationship between azoospermia factor ( AZF ) microdeletion of Y chromosome and azoospermia , the exact breakpoint of a severe Y-chromosome deletion was determined according to the physical map of AZF .

无精症患者的染色体异常分析无精症DAZ基因缺失研究

Analysis of Chromosomal Abnormality in Azoospermia Relationship between the entire DAZ genes as well as DAZ1 / DAZ2 deletion and azoospermia

目的研究无精症患者Y染色体的形态学改变及相应的无精子因子（azoospermiafactor，AZF）区域的微缺失位点，为无精症患者进行明确的遗传学诊断。

Objective To study the morphology of Y chromosome and microdeletion of the correlated specific azoospermia factor ( AZF ) region on Y chromosome in cases of azoospermia and to identify the genetic diagnosis made for male infertility patients .

GRTH基因c.852C/T多态性与无精症的相关性研究

Association of polymorphism of c.852C/T locus in GRTH with azoospermia

目的分析原发无精症和严重少精症患者Y染色体无精症因子C区（azoospermiafactorC，AZFc）DAZ基因（deleted-in-azoospermia，DAZ）部分拷贝缺失的类型与频率。

Objective To analyze the pattern and prevalence of partial copy deletion of deleted-in-azoospermia ( DAZ ) gene in the azoospermia factor C ( AZFc ) region of patients with idiopathic azoospermia or severe oligozoospermia .

目的探讨无精症患者的DAZ基因全缺失和DAZ1/DAZ2缺失。

[ Objective ] To investigate the relationship of the entire deleted in azoospermia ( DAZ ) genes as well as DAZ1 / DAZ2 deletion and azoospermia .

方法运用STSPCR法对25例无精症和27例严重少精症患者的Y染色体interval6的23个序列标签位点（STS）进行缺失筛查。

Methods Deletions in 25 azoospermic and 27 severe oligozoospermic Chinese patients were screened by STS PCR strategy . A total of 23 STSs in interval 6 of Yq , including 4 STSs in the deleted azoospermia gene ( DAZ ) region were analyzed .

目的探讨NYD-SP6基因在无精症患者和不同年龄人群中的表达及意义。

Objective To study the expression of NYD-SP6 gene in testes of azoospermia patients and normal men with different ages and the implication .

试验二应用数字基因表达谱技术（DGE）建立种公鸡无精症睾丸基因表达谱，初步分析差异基因的表达和功能。

The experiment used the application of digital gene expression profiling technology ( DGE ) to establish species of cock testis gene expression azoospermia , preliminarily analysing differences in gene expression and functional analysis .

方法应用多重PCR和PCR-RFLP技术，对252个正常生精男性和228例无精症患者的DAZ基因全缺失和DAZ1/DAZ2缺失进行了分析。

[ Methods ] The entire DAZ genes and DAZ1 / DAZ2 deletion were analyzed by multiplex polymerase chain reaction ( multi-PCR ) and polymerase chain reaction-restriction fragment length polymorphism ( PCR-RFLP ) in 228 infertile patients with azoospermia and 252 normospermic men as controls .

考虑到小鼠TEX11基因的缺失可以导致少精或者无精症，TEX11基因的缺失可能是导致男性不育症的遗传因素。

Given that disruption of TEX11 causes azoospermia , or non-measurable sperm levels in mice , mutations in the human TEX11 gene may be a genetic cause of infertility in men .

针吸细胞学检查对无精症睾丸的诊断价值

Evaluation of fine needle aspiration cytology on testis of azoospermia disease

无精症患者生精细胞检测和精浆生化测定

Analysis of Spermatogenic Cells and Biochemical Criterion in Patients with Aspermia