头孢菌素类抗生素

头孢菌素类抗生素的ADR监察

ADR survey of cephalosporins

在引起ADR的药物中，抗微生物药物出现次数居首位占65.6%，这其中又以头孢菌素类抗生素出现次数最多；

The leading drug that caused ADR was antibiotics ( 65.6 % ) . Among all of these antibiotics , the number of cephalosporins was highest .

目的：通过分析上海市药品不良反应中心收到的药品不良反应（ADR）报告中，头孢菌素类抗生素所致的ADR及其相关因素，了解该类药物ADR发生的情况，以减少ADR的发生。

Objective : To investigate the characteristics of adverse drug reaction ( ADR ) induced by cephalosporins through the analysis of ADR reports from ADR Monitoring Centre of Shanghai .

产ESBLs菌对青霉素类、氨曲南及头孢菌素类抗生素耐药率为56.2%～100%，具有多重耐药特点。

The resistance rates of ESBLs-producing isolates against penicillins , aztreonam and the third generation cephalosporins were about 56.2 % - 100 % , and almost multi-resistant .

头孢匹罗正是C-3位改造的成功范例，它以其优良的性能成为第四代头孢菌素类抗生素的代表。

A good example of C-3 modification is cefpirome , a representative example of the fourth-generation cephalosporins .

结果193株GBS菌均对青霉素类、头孢菌素类抗生素敏感；但青霉素和氨苄青霉素中介率均为17%；

Results Susceptibility testing revealed that none of the GBS isolates were resistant to β - lactam drugs , but 17 % isolates showed intermediate susceptibility to penicillin G and ampicillin .

3种头孢菌素类抗生素治疗下呼吸道感染的成本-效果分析

Cost-effectiveness analysis of three therapeutic schemes for lower respiratory tract infection

2003-2005年上海市头孢菌素类抗生素不良反应报告分析

Analysis of adverse drug reaction reports of cephalosporins during 2003-2005 in Shanghai

36例头孢菌素类抗生素不良反应中文文献分析

Analysis of Chinese Literature on Adverse Drug Reaction of Cephalosporins

头孢菌素类抗生素的电喷雾多级串联质谱分析

Analysis of Cephalosporins by Electrospray Ionization Multi-stage Tandem Mass Spectrometry

武汉市7家医院头孢菌素类抗生素的供应调查

Survey on the Supply of Cephalosporins in Seven Hospitals in Wuhan City

我院门诊药局2004&2007年头孢菌素类抗生素利用分析

Analysis of Cephalosporins Antibiotics Used in Outpatient Pharmacy During 2004-2007

第三代头孢菌素类抗生素临床安全用药分析

Analysis of Clinical Safety Application of The Third Generation Cefazolin

头孢曲松钠为第三代头孢菌素类抗生素，对肠杆菌科细菌有强大活性。

Ceftriaxone sodium is the third generation cephalosporin antibiotic .

目的研究成都市医院临床分离的铜绿假单胞菌对头孢菌素类抗生素耐药的情况与机制。

Objective : To study the resistance mechanisms of Pseudomonas aeruginosa to cephalosporins .

头孢菌素类抗生素致尿毒症患者抽搐发作12例临床分析

Clinical Analysis on Convulsive Seizures Caused by Using Cephalosporins in 12 Uremic Patients

头孢菌素类抗生素过敏反应临床前安全性评价的探讨

Discussion on the Pre-clinical Safety Evaluation of the Allergic Reactions in the Cephalosporin Antibiotics

3种头孢菌素类抗生素成本与效果的决策树分析

Cost-effectiveness decision analysis of 3 kinds of cephalosporins

头孢菌素类抗生素临床应用进展和合理用药

Clinical progress and rational use of cephalosporins

头孢菌素类抗生素生产过程中，产生大量母液。

A large amount of mother liquor was generated in the cephalosporin antibiotic manufacture process .

先锋5号禁用于已知对头孢菌素类抗生素过敏的患者。

Cetazolin sodium is contraindicated in patients with known hypersensitivity to cephalosporin group of antibiotics .

早期应用头孢菌素类抗生素对腹腔海水浸泡伤大鼠的救治研究

Treatment investigation into early application of cephalothin antibiotic to celiac seawater immersion wound of the rats

头孢菌素类抗生素应用分析

Analysis of application of Cephalosporins

目的：调查并分析武汉市7家医院头孢菌素类抗生素的供应情况。

OBJECTIVE : To investigate and analyze the supply situation of cephalosporins in 7 hospitals in Wuhan city .

结论：产生β-内酰胺酶是肺炎克雷伯杆菌对头孢菌素类抗生素耐药的机制之一。

Conclusions : Production of β - lactamase is one of the resistance mechanisms of Klebsiella pneumoniae to cephalosporins .

2003年肠球菌感染的88例病例中，应用头孢菌素类抗生素者为70例，占79%。

Among the 88 cases of enterococcal infection in 2003,70 cases had been treated with cephalosporins ( 79 % ) .

2005年河北省自然科学基金“新型头孢菌素类抗生素的设计与合成”主研。

Project funded by Natural Science Foundation of Hebei Province in2005 ," New Cephalosporins Design and Synthesis ", the main investigator .

结论产生β-内酰胺酶是这62株从成都医院分离的铜绿假单胞菌对头孢菌素类抗生素耐药的主要机制之一。

Conclusions : Production of β - lactamase is one of the resistance mechanisms of Pseudomonas aeruginosa from Hospital to cephalosporins .

药敏结果显示：对A群链球菌感染，临床应首选青霉素类、苯唑西林和头孢菌素类抗生素。

For the treatment of group A streptococcus infection . the clinical doctor should choose penicillin , oxacillin and cephalosporins first .

结论3种头孢菌素类抗生素中，头孢哌酮钠-舒巴坦钠是治疗下呼吸道感染的最佳药物。

CONCLUSIONS Cefoperazone-sulbactam sodium is the best one among the 3 antibiotics of cephalosporins in treating the lower respiratory tract infections .