毒性作用

黄曲霉毒素B1对大鼠肝脏毒性作用的病理学研究

Pathological study of toxic effect of aflatoxinb_1 on rat liver

目的观察邻氨基苯甲醚对中国仓鼠肺细胞（Chinesehamsterlungcells，CHL）的毒性作用。

Objective To observe the toxic effect of o anisidine on Chinese hamster lung cells .

能够抑制糖基化终末产物（AGE）的产生，以减少其毒性作用；

Restrain advanced glycation end products ( AGE ) and alleviate toxicity ;

多粘菌素B对眼局部组织毒性作用的实验研究

Local Toxic Effects of Polymyxin B on the Eye

维生素E对色拉油烟冷凝物致小鼠毒性作用的影响

Effect of vitamine on toxicity of salad oil vapor condensate in mice

维生素E拮抗铬致大鼠睾丸毒性作用的实验研究

Antagonistic effect of vitamin E on chromium toxicity in testis of rat

目的：探讨苯对小鼠骨髓细胞DNA基因的毒性作用。

Objective : To study the toxicity of benzene inhalation on DNA of bone marrow cells in mice .

结论毒鼠强诱导体内细胞DNA损伤可能是毒鼠强毒性作用机制之一。

Conclusion It is assumed that DNA damages of cells might be one of the toxicant mechanism of tetramine .

MTT法研究三种放射增敏剂对视网膜母细胞瘤的毒性作用

A study on the toxicity of three radiosensitizers on retinoblastoma cells by MTT assay

谷氨酸对原代培养的SD大鼠皮层神经元毒性作用量效关系研究

Study on dose-effect relationship of toxicity effect of glutamate on cortical neuron in primary cultured SD rats

抗-β2m抗体对肿瘤细胞毒性作用的研究

Cytotoxic Effects of Anti - β _2m Antibody on Tumor Cells

结论兔眼玻璃体注入的双氯芬酸钠大于或／和等于700μg时，对视网膜有毒性作用。

Conclusion There is toxic effect on the cone and rod systems of retina when the diclofenac sodium 's dosage is more than 700 μ g.

D-氨基酸氧化酶基因在K562细胞中的表达及其介导的细胞毒性作用的研究

Expression of D-amino acid oxidase gene in K562 cells and the cytotoxicity of D-Alanine to the cells

目的：探讨葡萄糖毒性作用对2型DM胰岛β细胞和胰岛素抵抗的影响。

Objective : To study the effects of glucose toxicity on insulin β cells and insulin resistance in type 2 DM .

结论HQ可致HLF细胞DNA和细胞核损伤，产生遗传毒性作用。

Conclusions Exposure to HQ could cause DNA and nucleus damage inducing genotoxic effects on HLF .

结论：Aβ的神经毒性作用有一氧化氮途径参与，褪黑素可通过降低一氧化氮产生和NOS活力来部分对抗Aβ的毒性作用。

Melatonin is in part against the neurotoxicity of A β by reducing the level of NO and the activity of NOS.

叔二苯哌啶拮抗MPTP对多巴胺神经元毒性作用的实验研究

Experimental study on budipine antagonizing the dopaminergic neurotoxic effect of MPTP

研究茶多酚（TP）对顺铂（DDP）所致肾毒性作用的保护作用。

Purpose To study the protective effects of tea polyphenols on kidney damage caused by cisplatin ( DDP ) .

目的研究鱼藤酮（rotenone）对多巴胺（DA）能神经元的早期毒性作用，并探索一种较理想的组织模型。

Objective To investigate the early neurotoxicity of rotenone on dopaminergic neurons and explore an ideal tissue model .

探讨苯乙酸（phenylaceticacid，PAA）对大鼠原代培养的皮质神经元的毒性作用及其作用机制。

The neurotoxic effect of phenylacetic acid ( PAA ) on primary cultured cortical neurons and its underlying mechanism were investigated .

此外，Rd还可通过抑制神经元氧化应激损伤反应而保护神经元，使其免受Aβ的毒性作用。

In addition , Rd could also inhibit neuronal oxidative stress response and protect neurons against the toxic effects of A β .

本文报道以30、50、70和90mg/kg马杜霉素剂量水平添加到饲料中饲喂AA肉鸡，研究马杜霉素对肉鸡的毒性作用及其在鸡组织中的残留消除。

The toxicity and residue elimination of maduramicin were evaluated by feeding AA broiler chickens with 3.0,5.0,7.0 and 9.0mg/kg maduramicin in diet , respectively .

结论：MA对大鼠中枢神经系统多脑区神经元有明显的毒性作用，可导致上述脑区DA含量下降和大鼠行为改变。

Conclusion : MA has obvious neurotoxicity on multiple regions of the rat brain , and can cause neuron injuries , DA depletion and behavioral changes .

本文研究1-甲基-4-苯基-1，2，3，6-四氢吡啶（MPTP）对体外培养大鼠中脑多巴胺（DA）神经元的毒性作用。

The toxic effects of1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine ( MPTP ) to rat mesencephalic dopaminergic ( DA ) neurons were studied in vitro .

结论MTT法用于测定细胞毒性作用具有快速、正确等优点。

Conclusion The method of MTT can be used to measure neuron cytotoxicity . The main advantages of this assay are its rapidity and precision .

棉酚对罗非鱼（Oreochromisniloticus））离体精子毒性作用的研究

Effect of Gossypol on Survival of Spermatozoa of Tilapia Oreochromis niloticus in Vitro

人参皂苷Rg1激活PI3K/Akt信号通路对6-OHDA毒性作用的影响

Ginsenoside Rg1 protects against 6-OHDA-induced toxicity via the activation of pi3k / akt signaling pathway

结论人参皂甙Rb1和Rg1在较高浓度时对体外培养的大鼠胚胎有一定的毒性作用。

Conclusion At higher concentration , ginsenoside Rb1 and Rg1 has developmental toxicity on rat embryos .

【方法】作者采用MTT法对抗β2m抗体在体外对肿瘤细胞毒性作用进行的初步探讨。

The cytotoxic effects of anti - β 2m antibody on tumor cells in vitro were studied preliminarily by monotetrazolium ( MTT ) method .

结论胰岛素能导致HPMC损伤、诱导凋亡，同时在一定范围内可缓解高糖对HPMC的毒性作用。

Conclusion Insulin can injury HPMC and induce apoptosis as well as protect HPMC from toxicity of high glucose .