基因调控

X染色体失活&一种特殊方式的基因调控

X Inactivation : A Special Form of Gene Regulation

这是基因调控是由控制基因的表观遗传完成的，并没有改变DNA。

This gene regulation is accomplished by epigenetic processes that control gene expression without altering DNA .

凋亡（apoptosis）是指细胞在一定的生理或病理条件下，遵循自身的程序，由基因调控的主动死亡过程。

The apoptosis is referred to an active death procedure mediated by genes on some kinds of physical and pathological state .

用FCM聚类和非参数回归方法推断基因调控网络

Inference of Gene Regulatory Network Using FCM Clustering and Nonparametric Regression Algorithm

结果肿瘤细胞对辐射的敏感性及辐射增敏与辐射后细胞内DNA损伤修复水平及细胞周期有关，并受多基因调控。

Results The radiosensitivity and radiosensitivity-related therapy was connected with post-radiosensitivity DNA damage , rehabilitation , cell period , and multigene regulation in the tumor .

脑血管疾病患者IL-6基因调控区-174G/C多态性研究

A Clinical Study on G / C Polymorphism at 174 of the Interleukin-6 Gene in Cerebrovascular Patients

乳清酸蛋白基因调控序列的鉴定及转基因小鼠乳腺表达G-CSF载体的构建

WAP Gene Identification and Construction of Vectors Expressing Human G CSF

随着反义RNA的发现及对其研究的深入，反义RNA技术已被广泛应用于基因调控的研究中。

With the discovery of antisense RNA and further research , antisense RNA technique has been applied in the study of gene regulation .

糖尿病心肌细胞凋亡是糖尿病心肌损伤的重要病理特征，且与FAS／Bcl-2基因调控有关。

Diabetic myocardial apoptosis is an important pathologic character of diabetic myocardial damage and is associated with Fas / Bcl-2 gene control .

筛选、鉴定基因组中的调节片段和它们相应的DNA结合蛋白，阐明这些元件的结构与功能关系，是基因调控研究的主要内容。

One major aim of gene expression regulation research is to isolate and identify genomic regulatory sequences as well as their protein companions and to elucidate the structure basis of their functions .

大鼠20αHSD基因调控序列的克隆与检测

Cloning and assay of regulating sequence of the rat 20 α hsd gene

α（2A）-肾上腺素能受体基因调控区单核苷酸多态性对基因转录活性的影响

The Influence of SNP in Regulation Region of α _ ( 2A ) - Adrenergic Receptor Gene on Transcription Activity

花器官高表达转录因子的克隆将为研究TCP基因调控植物花发育和花形态建成提供新的物质基础。

The cloning of the new member of TCP transcription factor family will provide new base of material for the research of plant flower development regulation and flower tissue forming .

由于三链DNA可能存在于生命体系内，并且提供了基因调控、人造限制性内切酶以及阻止DNA和蛋白质结合等的新方法。

DNA triplexes have been attracting considerable attention in recent years because more and more evidence supports the existence of triplex DNA in vivo and the possible application of triplex DNA as artificial endonuclease , gene regulation .

利用自由权值矩阵和LMI方法，首先得到了几个时滞区间相关和时滞导数相关/无关的时滞基因调控网络的全局渐近稳定判定条件。

First , by employing some free-weighting matrices and linear matrix inequalities , new delay-range-dependent and delay-derivative-dependent / independent stability criteria are derived .

用于细胞基因调控研究的RNA干涉技术和基因诱导表达方法，现在移植到了转基因动物中，并获得了理想结果。

RNA interference methods and gene inducible expression techniques to use on study of gene regulations in cells are transferred to making transgenic animals , and the ideal research results are gained .

平面问题在印制电路板的设计和大规模集成电路（VLSI）的布线方面有着重要的应用，对于很多可视化问题，例如基因调控网络的可视化也有着重大的意义。

It is widely used in designing printed circuit boards , routing very-large-scale integration ( VLSI ) circuits and very important to the visibility of the Gene Regulatory Network .

另外，Egr-1基因调控序列具有辐射可诱导特性，这一特点使其有了潜在的临床和基因工程生产应用前景。

Additionally , the radiation-inducible property of the Egr-1 gene regulating sequence confers potential clinical and genetic engineering sues .

本文从影响人胚胎干细胞体外向生殖系分化的基因调控和干细胞小生境（niche）方面进行综述，并指出胚胎干细胞在生殖医学及不孕治疗中的研究方向和应用前景。

This review focuses on the stem cells niches and genes regulating the hES differentiation toward germ cells , as well as the recent advance and application on the reproductive medicine and therapy of infertility .

采用引物延伸法，对ApNPV核多角体蛋白mRNA转录起始点进行了测定，确定其位于该基因调控序列12个核苷酸高保守区的nt&50位点与AcNPV相似。

The mRNA transcriptional start site was determined by primer extension , which located at nt - 50 in the high conserved 12-mer nucleotide domain , similar as AcNPV .

所克隆的奶山羊BLG基因调控区与山羊BLG伪基因显著不同，其同源性仅为83%（上游调控区）和88%（下游调控区）。

The dairy goat gene differed significantly from goat BLG pseudo gene with a homology of only 83 % ( upstream region ) and 88 % ( downstream region ), respectively .

结果：73例脑血管疾病患者IL-6基因调控区-174位均为GG型；血清白细胞介素&6水平升高，与正常人血清对比，差异显著。

Results : The genotype at 174 of the Interleukin-6 Gene in 73 cases of cerebrovascular patients is normal GG , but the contents of IL-6 in serum of 73 cases of cerebrovascular patients were much higher than that in the control group .

结论（NZB×NZW）F1小鼠自身抗染色质抗体的产生受多基因调控，候选易感基因不仅来自于NZB，也来自于NZW。

Conclusion : Susceptibility allele of anti-chromatin antibody in ( NZB × NZW ) F1 mice was comprised of multiple genes and the candidate susceptibility genes were derived from both NZB and NZW strain .

基因调控网络是生物动态系统，它的基本特征是稳定性，具有重要的研究意义。本文考虑基因调控网络的非线性、时滞、随机干扰等特点，建立具有Lurie系统形式的连续时间基因调控网络模型。

GRNs are biochemical dynamical systems , and their basic feature is stability , which is of great research significance . A continuous-time GRNs model is proposed by considering nonlinear , time delay and stochastic perturbation , which has a form of Lurie system .

神经发育早期暴露PBDEs可损害感觉运动、学习与记忆、自主行为发育等。细胞凋亡是一种由基因调控的细胞自主性死亡过程，有助于选择性消除体内生理性和病理性异常细胞。

Exposure to PBDEs in early neural developmental stage may affect sensorimotor activity , learning and memory , and development of independent behavior . Apoptosis , a programmed cell death model under genetic control , contributes to selective elimination of cells in physiological and pathological situations .

总之，儿童性早熟可能是一种涉及到基因调控和表达的疾病，滋阴泻火中药合剂可从分子水平，在多个层次调整异常的HPGA功能。

In sum , the expression and regulation of certain genes may be involved in the pathogenesis of precocious puberty , and the targets of CHM that effectively treat this disease may just at the level of gene .

细胞凋亡及其基因调控在脑血管痉挛中的研究

Study about Cell Apoptosis and its Gene Regulation in Cerebral Vasospasm

组蛋白修饰与干扰素γ应答基因调控的关系

The relationship between histone acetylation modification and IFN-gamma responsive gene regulation

复杂基因调控网络常呈现出非线性动力学行为。

Complex gene regulatory networks often show some nonlinear dynamical behavior .

牙龈卟啉单胞菌类胰蛋白酶基因调控和表达

Regulation and expression of trypsin-like protease gene of Porphyromonas gingivalis