合理用药

如上设计流程不但使系统实现自学习，而且使合理用药系统学习效率得到了提高。

This kind of design process not only makes the system realize self-learning , but also makes the system of rational administration of drug improve the learning efficiency .

合理用药是指根据疾病种类、病人状况和药理学理论选择最佳的药物及其制剂，制定或调整给药方案，以期有效、安全、经济地防治和治愈疾病的措施。

Rational administration of drug means making best choice of medicine and the preparation according to sickness category , conditions and pharmacology theory in order to get the valid , secure and economic measure to prevent and charm away disease .

采用美康公司合理用药软件系统（PASS）网上监测相关用药医嘱。

Meantime prescription automatic screening system ( PASS ) was used for monitor relative prescriptions of drugs .

目的利用PASS监控我院医嘱用药，以提高临床合理用药水平。

Objective To monitor medical orders by using PASS so as to improve rational use rate of drug .

合理用药是降低ADR发生的关键；

Rational drug use is the key to lower ADR .

目的分析利巴韦林治疗SARS患者与心率减慢的关系，为临床合理用药提供参考。

Objective : To investigate whether bradycardia is related with ribavirin treatment in SARS patients .

结论PASS可以方便快捷地辅助医药工作者审核医嘱，减少药源性疾病发生，促进合理用药。

CONCLUSION The PASS can be a convenient fastly assistant to medicinal workers and help to avoid the medicine source diseases and may promote rational drug use .

结论：通过AID使用管理，减少了AID的滥用，提高了医院合理用药水平。

Conclusion : Through the management and administration of AID , the abuse of AID decreased and the level of using AID rationally has been improved .

目的在不同pH的介质下对硝苯地平缓、控片的释放度进行考察，为合理用药提供依据。

Objective In order to provide a rationale of drug usage , we studied in vitro dissolubility of slow-release and controlled-release tablet of nifedipine in different pH of dissolution media .

结论：PASS系统可有效地监测医嘱中的不合理用药，从而预防和减少药物不良事件的发生，值得临床推广应用。

CONCLUSION : PASS can efficiently monitor the irrational drug use in medical order , hence prevent and reduce adverse drug reactions , therefore it should be widely used in clinic .

结论：医疗工作者应协同做好ADR监测工作，促进临床合理用药。

CONCLUSION : Medical worker should work cooperatively in the monitoring of ADR and promote rational drug use in the clinic .

结论医院相关专业技术人员应重视ADR监测工作，促进临床合理用药。

Conclusion The technologist in hospital should attach the stress to monitoring ADR for facilitating the rational use of clinical drug .

目的研究社区获得性甲氧西林耐药金黄色葡萄球菌（MRSA）感染的临床特征及分离菌的耐药情况，指导临床合理用药。

Objective To investigate the clinical characteristics and antibiotics resistance of community-acquired MRSA and to guide antibiotics chemotherapy in clinics .

通过引进并融合疾病分类编码、合理用药监测、麻醉及ICU/CCU联机信息采集、PDA等新功能，提高了临床信息采集的效率和信息质量，也极大地提高了临床信息系统的应用水平。

By establishing clinical coding system , PASS , online information gathering system and PDA , the information quality and application level of CIS can be elevated .

目的调查枣庄市支气管哮喘（BA）患者的药物使用情况，为BA的合理用药和规范防治提供科学依据。

Objective To investigate the medications in patients with bronchial asthma ( BA ), so as to provide the scientific evidence for the standardized prevention and the reasonable medication .

目的总结我院2009年药品不良反应（ADR）监测情况，促进临床安全、合理用药。

Objective To enhance the level of safe and rational use of drugs throgh investigating the adverse drug reactions ( ADR ) cases in our hospital in2009 .

目的分析女性生殖道感染者解脲支原体（UU）和人型支原体（MH）检出情况及体外耐药性，以指导临床合理用药。

Objective : To analyse drug resistance and detection of ureaplasma urealyticum ( UU ) and mycoplasma hominis ( MH ) among women with genital infection .

方法：抽查我院2003～2005年住院病人医嘱处方5000张，根据合理用药监测系统（PASS），临床药理知识及文献资料，对不合理处方进行分类和统计分析。

METHODS 5000 inpatient prescriptions in 2003 ~ 2005 in our hospital were sampled ; in which , the irrational prescriptions were classified and analyzed statistically based on prescription automatic screening system ( PASS ), pharmacological knowledge and literatures .

结论利用TCD进行动态观察脑血流变化，对临床早期明确诊断脑损伤程度，指导临床早期及时合理用药和停药以及对预后判断有明确的意义。

Conclusion Value of estimating cerebral blood velocity by TCD on diagnosing extent to brain injury , instructing medicine in early time and judging prognosis is significant .

目的探讨线粒体途径在肿瘤坏死因子凋亡诱导配体（TRAIL）诱导结肠癌细胞凋亡过程中的调节作用，为临床合理用药提供理论指导。

Objective To explore the effects of mitochondrial pathways on apoptosis in colon carcinoma cells induced by Tumor necrosis factor related apoptosis inducing ligand and offer evidences for TRAIL application in clinic .

结论检测TMS的MEP可以协助诊断癫痫，指导癫痫合理用药。

Conclusion MEP induced by single pulse TMS might be valuable for assisting the diagnosis of epilepsy and directed to take medicine rationally .

HBV感染患者在治疗前后有必要检测是否存在HBVYMDD变异株感染，为指导临床科学合理用药和制定治疗方案提供依据。

To guide reasonably antival therapy in clinic and make therapic remedy , it is necessary for HBV-infected patients before or after antiviral therapy to detect HBV YMDD mutations .

结论加强对ESBLs菌株及其耐药率监测，能指导临床合理用药，是预防和控制ESBLs细菌感染的重要措施。

Conclusion Strengthening the monitoring of bacterial drug resistance , is the important measure to guide clinical use of antibiotics and control ESBLS - producing bacteria infection .

结论对呼吸道疑似病毒性感染患儿，作血清学早期待异性IgM抗体检测，可即早明确诊断，以利合理用药，避免治疗盲目性。

Conclusions special RSV-IgM antibody screening in early period of infection can diagnose RSV infection in children with respiratory infection , to avoid aimless treament , to facilitate reasonable drug use .

目的：探讨病毒性心肌炎（VMC）并发心律失常合理用药治疗方案。

Objective : To explore the different drug therapies available for the treatment of arrhythmias in patients with virus myocarditis ( VMC ) .

多因素非条件Logistic回归分析表明，保守治疗方式、入住ICU、罹患感染、肿瘤、脑部肿瘤、自身免疫疾病、联合用药是不合理用药的相关因素。

Multivariate unconditional logistic regression analysis showed that the conservative treatment , check the ICU , risk of infectious , cancer , autoimmune diseases , and the combination are related with irrational drug use . 3 .

结果104例ADR中，皮肤及附件器官损伤居多，其次是消化系统的ADR，一方面为不合理用药或用药不当所造成；

RESULTS : in104 cases of ADR , the most allergic reactions , followed by the digestive system of ADR , On the one hand , unreasonable use or caused by inappropriate medication ;

结论：UU存在多重耐药，对UU进行药敏监测对指导临床合理用药及防止耐药株的发生有重要意义。

CONCLUSION : UU shows multiple drug resistance . The determination of the susceptibility of UU to antimicrobial agents can instruct reasonable medication and prevent the occurrence of drug resistance .

结论新生儿VAP发生率高，应避免危险因素或针对危险因素重点监控，并根据病原学及药敏结果合理用药。

Conclusion The occurrence of VAP is high , risk factors should be monitored , and antimicrobial agents should be used according to pathogenic detection and antimicrobial susceptibility test .

目的：监测我院下呼吸道产超广谱β-内酰胺酶（ESBLs）菌株耐药状况，指导临床合理用药。

Objective : To analysis the status of drug resistance of strains of extend spectrum β - lactamase ( ESBLs ) which isolated from the inpatients with lower respiratory tract infection .