反应元件

  • 网络response elements;GRE;PPRE;RARE
反应元件反应元件
  1. 目的本文旨在对NGAL基因启动子区及其附近是否存在TPA反应元件进行研究。

    Objective The TPA response elements in NGAL promoter region and the sequences surrounding its promoter region will be determined .

  2. 结论:能方便地获得TTF1体外翻译蛋白,为进一步研究TTF1蛋白与相应的DNA反应元件及其他转录因子的相互作用奠定了基础。

    Conclusion : Expression of TTF1 in vitro can be used in the further research of interaction of TTF1 and its DNA response elements and others transcription factors .

  3. 维甲类X受体与维甲酸反应元件β2RARE结合的研究

    Study on the binding of retinoid X receptor with β 2 rare

  4. cAMP反应元件结合蛋白在药物依赖形成中的作用

    Role of cAMP response element binding protein in the development of drug dependence

  5. 缓激肽诱导胶质瘤细胞内cAMP反应元件结合蛋白磷酸化的实验研究

    Phosphorylation of cAMP response element binding protein in glioma cells induced by bradykinin

  6. cAMP反应元件结合蛋白与神经病理性疼痛

    CAMP response - element binding protein and neuropathic pain

  7. 扩展莫尼茨绦虫反应元件结合蛋白基因的克隆和cDNA序列分析

    An Isolation and Sequence Analysis of the cDNA Encoding Moniezia expansa CREB-Binding Protein

  8. cAMP反应元件结合蛋白介导磷酸化细胞外信号调节激酶在神经病理性痛形成中的作用

    CAMP response-element binding protein participates in the phosphorylated extracellular signal-regulate kinase mediated neuropathic pain

  9. 脂多糖刺激血管内皮细胞激活cAMP反应元件结合蛋白

    Activation of transcription factor cAMP response element binding in vascular endothelial cells induced by lipopolysaccharide

  10. 人神经母细胞瘤株中β-淀粉样前体蛋白基因IL-1反应元件的研究

    The Research of IL-1 Responsive Element of APP Gene Promoter in Neuronal cell

  11. 乙烯反应元件结合蛋白属于植物特有的一个转录因子家族,这个家族保守的DNA结合域称为ERF结构域。

    Ethylene-responsive element-binding proteins ( Erebus ) are members of a family of plant transcription factors .

  12. 急、慢性乙醇处理后大鼠伏核内cAMP反应元件结合蛋白磷酸化的变化

    Changes in the phosphorylation of cAMP response element binding protein in the rat nucleus accumbens after acute and chronic ethanol administration

  13. 用IREFINDER算法在非翻译区搜索人和小鼠的铁反应元件

    IRE_FINDER & Computational Search of Iron Response Element in Human and Mouse UTRs

  14. cAMP反应元件和核因子-κB联合转染C6胶质细胞株。

    Moreover , cAMP response element ( CRE ) and nuclear factor ( NF ) - κ B were combined to transfect C6 glial cell strains .

  15. 采用免疫组织化学染色观察了纹状体边缘区蛋白磷酸酶1、磷酸化的cAMP反应元件结合蛋白表达的改变。

    The changes of the expressions of protein phosphatase 1 and phosphorylated cAMP responsive element binding protein in the marginal division of striatum were observed with immunohistochemical staining .

  16. 阻断NMDA受体可增强皮质酮对海马脑源性神经营养因子表达的抑制:cAMP反应元件结合蛋白的作用

    Blockade of NMDA receptor enhances corticosterone-induced downregulation of brain-derived neurotrophic factor gene expression in the rat hippocampus through cAMP response element binding protein pathway

  17. 乙烯反应元件结合因子(Ethylene-responsiveelementbindingfactors,ERFs)是植物所特有的转录因子,参与了植物各种生理调节,研究发现很多的ERFs成员参与了抗逆的调节,如干旱、低温、高渗等。

    Ethylene-responsive element binding factors ( ERFs ) are members of a novel transcription factors super family that are specific to plants .

  18. cAMP反应元件结合蛋白(cAMPresponseelement-BindingProteins,CREB)是一个哺乳动物转录因子家族,通过cAMP反应元件(cAMPresponseelement,CRE)调节cAMP和钙离子依赖性基因的表达。

    CAMP response element-binding ( CREB ) proteins are a family of mammalian transcription activators that mediate cAMP and calcium-dependent gene expression through the cAMP response element ( CRE ) .

  19. MYC反应元件修饰的人端粒酶逆转录酶(hTERT)启动子在骨肉瘤基因治疗中的应用基础研究

    The Research on Osteosarcoma Gene Therapy by Human Telomerase Reverse Transcriptase ( hTERT ) Promoter Modified with MYC-responsive Elements

  20. AP1反应元件的确定及在细胞角蛋白13基因表达调控中的作用

    Identification of AP1 cis-element and transcriptional effect on cytokeratin 13 gene expression

  21. 我们发现当CRH启动子区的半雌激素反应元件和cAMP反应元件(CRE)突变后,ER介导的CRH启动子的激活也被降低。

    When the ERE half sites and the cAMP regulatory element ( CRE ) in the CRH promoter were disrupted , ER-mediated up-regulation of CRH promoter activity reduced .

  22. 应用萤光素酶报告基因系统证明了本实验所鉴定的NF-κB反应元件是nNOS1f启动子中一个强大的正调控元件,同时它在TSA引起的nNOS1f启动子的转录激活中发挥重要作用。

    Results of luciferase assay showed the identified NF - κ B responsive element acted as a powerful positive regulation element and took an important part in TSA-induced activation of nNOS 1f promoter . 7 .

  23. AtRA可激活异二聚体RAR/RXR,后者通过识别和结合维甲酸受体反应元件(RARE),进而引起靶基因的转录激活或转录抑制。

    Initially , atRA activates a heterodimer RAR / RXR , which further recognizes and binds to retinoic acid receptor response element ( RARE ) consensus sequence , thereby activating or repressing target gene transcription .

  24. 目的:探讨低硒饮食对发育期大鼠大脑皮层和海马的脂质过氧化物和转录因子cAMP反应元件结合蛋白(CREB)的影响。

    Object : To observe the changes of lipid peroxide and cAMP Response Element-Binding Protein ( CREB ) in the cortex and hippocampus of developing rat induced by selenium deficiency diet .

  25. 用PlantCare软件进一步作顺式作用元件分析,发现两段启动子序列包含大量光反应元件及脱落酸、赤霉素、水杨酸、生长素、乙烯等激素应答元件。

    After this , we analysised the upstream regulatory elements in the two promoter fragment with software of Plant Care , and found lots of light - responsive element , and abscisic acid-responsive element , auxin - responsive element , ethylene-responsive element , gibberellin-responsive element , salicylic acid-responsive element .

  26. 环磷酸腺苷反应元件结合蛋白(CREB)作为一种重要的核转录因子,在学习记忆中有着重要的作用。

    CAMP response element binding protein ( CREB ) was one of the most important transcription factor , which had important effect on learning-memory .

  27. 铁反应元件(IRE)具有的高度保守的RNA茎环结构,是胞质中IRE结合铁调控蛋白(IRP)的位点。

    The iron response element ( IRE ) is a highly conserved RNA stem loop structure . It is the binding site of iron regulatory protein ( IRP ) .

  28. 以含雌激素反应元件的荧光素酶(ERE-LUC)为报告基因,通过检测荧光素酶活性来确定MDM2是否对ER有转录调节因子的作用。

    The effect of MDM2 on the transcriptional activity of ER was detected by the reporter gene containing estrogen responsive elements luciferase ( ERE-LUC ) .

  29. 雌激素也可与雌激素受体形成复合物,直接与TERT基因启动子区域内的退化雌激素反应元件结合反式激活端粒酶。

    Estrogen could activate telomerase directly by forming estrogen / estrogen receptor complex binding to imperfect palindromic degenerate estrogen responding element in promoter region of TERT gene .

  30. 视黄酸和α-干扰素对带有视黄酸反应元件的LUC报告基因表达的调控作用

    Effect of retinoic acid on the expression of luciferase reporter gene in HL-60 cells transfected with the reporter plasmids containing retinoic acid response element