利巴韦林

结果：薄荷脑和尿素对利巴韦林有非常显著的促进透皮吸收作用（P＜0.01）。

RESULTS : Menthol and urea markedly enhanced the percutaneous absorption of ribavirin ( P < 0.01 ) .

HPLC法测定抗病毒药物口罩含药湿巾中利巴韦林含量

Determination of ribavirin in antivirotic drug-mask by HPLC

HPLC测定利巴韦林颗粒的含量

Determination of Ribavirin granules by HPLC

利巴韦林在体外对小鼠脾细胞NK活性的影响

Effect of ribavirin on NK activities of murine spleen cells in vitro

利巴韦林治疗SARS患者致心率减慢的病例对照研究

The case-control study of relationship between ribavirin therapy and bradycardia in SARS patients

目的比较利巴韦林等五种药物对汉坦病毒（HV）的体外抑制作用。

Objective To compare the antiviral activity of five drugs in vitro .

目的分析利巴韦林治疗SARS患者与心率减慢的关系，为临床合理用药提供参考。

Objective : To investigate whether bradycardia is related with ribavirin treatment in SARS patients .

在开始单独使用利巴韦林治疗后，所有患者血清样本中检测不到HEVRNA水平。

Three months after ribavirin therapy commenced , HEV RNA was undetectable in serum samples from all patients .

目的：建立RP-HPLC法测定利巴韦林滴眼液中利巴韦林含量的方法。

OBJECTIVE : A RP-HPLC method for determination of ribavirin in ribavirin eye drops was developed .

结论：利巴韦林和DS联合给药对治疗小儿轮状病毒肠炎安全有效。

Conclusion : Combinative administration of ribavirin and DS is an effective and safe therapeutical scheme for rotavirus enteritis .

利巴韦林（Ribavirin）是一种嘌呤核苷类似物，具有广谱抗病毒作用。对多数DNA、RNA的复制有抑制作用。

Ribavirin , an antiviral agent of nucleoside analog , has wide efficacy against virus and restrains lots of DNA and RNA copy .

结果清肺口服液具有明显抗RSV的作用，与利巴韦林比较差异无统计学意义；

Result Qingfei Oral Liquid had obvious effection of anti-RSV , showing no significant difference compared with Ribavirin .

目的考察25℃下6h内，利巴韦林注射液与清开灵、穿琥宁、鱼腥草等3种中草药注射液的配伍稳定性。

OBJECTIVE To inspect the stability of ribavirin mixed with three chinese herbal medicine injections at 25 ℃ for 6 hours .

干扰素（IFN）联合利巴韦林或单独应用治疗方案被认为是治疗丙型肝炎病毒感染患者的标准抗病毒治疗方案。

Interferon ( IFN ) therapy with or without ribavirin treatment is well established as a standard antiviral treatment for hepatitis C virus ( HCV ) - infected patients .

如在临床疾病早期给予抗病毒药利巴韦林（ribavirin），这对拉沙热是有效的治疗。

The antiviral drug ribavirin is effective treatment for Lassa fever if given early on in the course of clinical illness .

目的评价利巴韦林、更昔洛韦、单磷酸阿糖腺苷3种常用抗病毒药对家兔外周血血红蛋白含量（Hb）和网织红细胞比率（Ret）的影响。

Objective To assess the effects of 3 commonly used antiviral drugs ribavirin , ganciclovir and vidarabine monophosphate on the erythropoiesis in the rabbits .

目的观察干扰素α-1b（IFNα-1b）与利巴韦林（ribavirin）联合治疗慢性丙型肝炎（CHC）的疗效及安全性。

Objective To study the efficiency and safety of interferon alpha-1b and ribavirin in the treatment of chronic hepatitis C ( CHC ) .

方法采用MTT法，以利巴韦林为对照组，观察清肺口服液及不同给药方式对RSV的拮抗作用。

Method With Ribavirin as the control , the antagonistic effect of Qingfei Oral Liquid and different administration methods on RSV infection were observed by MTT technology .

目的：对静脉高效丙种球蛋白（IVIG）、α-干扰素（IFN-α）及利巴韦林治疗小儿传染性单核细胞增多症疗效进行评价。

Objective : To evaluate the clinical effect of IVIG , IFN - α and ribavirin on the children with infectious mononucleosis .

结论以干扰素α联合利巴韦林治疗中国人HCV/HIV患者，用药24周的抗HCV效果不低于两种药物联合治疗单独HCV患者的效果，并有一定的抗HIV作用。

Conclusions IFN α - 2b and RBV combination therapy showed similar anti-HCV effects during the 24 week treatment for HCV-HIV and HCV infected patients , and some anti-HIV effect was also observed .

对照组24例，用利巴韦林5mg·kg-1，用法同治疗组。疗程均为5d。

At the same , control group was administered with ribavirin 5 mg · kg - 1 . The period of treatment was 5 d.

方法：采用人流感病毒A型（H1N1）滴鼻感染小鼠，以利巴韦林作为阳性对照药，对知母宁抗病毒活性进行评价。

Method : The mice were infected with human influenza A virus ( H1N1 ) by nasal drip . The antiviral capacity of chinonin was evaluated by using ribavirin as the positive reference drug .

方法：采用体外扩散实验考察不同浓度的Trans对利巴韦林、依诺沙星、加替沙星，盐酸左氧氟沙星和奥沙普秦兔角膜透过率的影响。随着pH值的降低，哌仑西平角膜透过率逐渐提高。

METHODS : The effects of Trans on the corneal permeability of drugs were investigated in vitro , using isolated rabbit corneas . The penetration rate was found to dependent on the pH of pirenzepine solution . The lower the pH , the higher the rate .

建立了利巴韦林泡腾颗粒含量测定的HPLC方法。以PE-PackC18为色谱柱，水为流动相，检测波长为207nm。

A HPLC method for determination of Ribavirin Effervescent Granules was established , using a PE-Pack C18 column with the mobile phase of water , at the detection wavelength of 207 nm .

以0·2%布比卡因20ml（含加入醋酸泼尼松龙30mg、利巴韦林0·4g，弥可保1mg）在皮损疼痛区皮下浸润，2次/d。

Local infiltration I skin lesion areas were performed two time per week with 20 ml of 0.2 % bupivacaine solution containing acetic acid hydroprednisone 30 mg , ribavirin 0.4 g and methycobal 1 mg .

通过树脂静态、动态吸附实验，确定了LSD-311树脂柱吸附分离回收利巴韦林的工艺条件。

Through static and dynamic experiments of resin adsorption , the preferable technical conditions of reclaiming ribavirin by LSD-311 resin are ascertained .

方法以利巴韦林作阳性对照药物，采用存留细胞结晶紫染色法测定连花清瘟胶囊不同给药方式对甲型人流感病毒H3N2的体外抑制作用及其时效关系。

Methods Under different administration modes , the inhibitory effect of Lianhua Qingwen Capsule on human influenza A virus ( H3N2 ) in vitro and its time-effect relationship were assayed by crystal violet staining assay with ribavirin as positive reference drug .

方法：60例流感疑似病例随机分为2组，治疗组30例口服奥司他韦2mg/（kg.次），2次/d，对照组30例静脉滴注利巴韦林10mg/（kg.d），疗程均为5d。

Methods : 60 patients were divided into 2 groups randomly . Treatment group of 30 cases were given oseltamivir 2 mg / kg , twice daily by mouth ; control group of 30 cases were given ribavirin 10 mg / ( kg · d ) by vein .

结果0.2、0·4mgAs-ODN和0.8mg利巴韦林能降低RSV感染小鼠肺组织病毒滴度，空斑抑制率分别为34.48%、46.75%和23.02%，与感染对照组比较差异显著（P<0·05）。

Results Pulmonary titer of mice treated with 0.2 , 0.4 mg AS-ODN or 0.8 mg Ribavirin decreased as compared with that of infected control mice , and the plaque forming inhibition ratio was 34.48 % , 46.75 % and 23.02 % respectively .

利巴韦林与3种中草药注射液配伍稳定性考察

The stability of ribavirin mixed with three chinese herbal medicine injections