促癌物
- 网络promoter;tumor promoter
促癌物
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人乳头状瘤病毒与促癌物协同作用诱发人胚宫颈细胞恶性转化研究
Induction of human cervical carcinoma by human papilloma virus and tumor promoters
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提示这些毒素可能是环境中的非基因毒性促癌物。
It suggested that the toxins may be a kind of nongenotoxic carcinogen .
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结论在促癌阶段,促癌物PB能抑制凋亡,诱导抗凋亡基因bcl-2mRNA表达上调和促凋亡基因BAXmRNA表达下调,提示凋亡抑制可能是促癌的机制之一。
Conclusion Phenobarbital might suppress apoptosis by inducing bcl-2 mRNA up-regulation , and bax mRNA down-regulation suggesting that suppression of apoptosis may be one of the mechanism of cancer promotion .