中毒性心肌炎

黄芪注射液对小鼠中毒性心肌炎的保护作用

Protective Effect of Astragalus Injection on Adriamycin-induced Toxic Myocarditis in Mice

婴幼儿并发肺炎和中毒性心肌炎较多见，而3岁以上儿童并发中毒性肝炎较多见。

Pneumonia and toxic myocarditis were common in infants and toddlers , while toxic hepatitis was common in children over three years old . 5 .

结论：心肌尔康口服液对中毒性心肌炎具有保护作用，这种保护作用可能与其降低血清心肌酶活性、降低心肌组织中MDA含量和增强SOD活性有关。

The protective effect may be related to decreasing myocardium enzyme activities in serum , decreasing MDA content while increasing SOD content in myocardium tissue .

方法建立小鼠阿霉素（ADR）中毒性心肌炎模型，记录实验结束时小鼠存活率和心电图改变，测定血清肌酸激酶同工酶（CK-MB）、肌酸激酶（CK）和谷草转氨酶（GOT）活力，同时进行形态学观察。

Methods ADR was injected intraperitoneally to induce myocardium injury model in mice . The survival rate and the ECG changes were observed . The activities of creatine kinase isoenzymes ( CK-MB ), creatine kinase ( CK ) and glutamic oxaloacetic transaminase ( GOT ) were measured .

结果治愈15例，死亡5例。死亡原因：窒息3例，中毒性心肌炎2例，肺炎1例。

Results Cure 15 cases , death 5 cases , death cause : asphyxia 3 cases , toxicosis myocarditis 2 cases , pneumonia 1 case .

本文还着重于病毒性心肌炎和中毒性心肌炎的鉴别诊断，并认为潜在性病毒性心肌炎是存在的。

Moreover , the authors also referred to the necessity of the differential diagnosis between viral and toxic myocarditis in childhood in pediatric practice , seriously indicating the probability of the potential existence of viral myocarditis in such clinical situation .

儿童伤寒的并发症发生率高，较常见的是中毒性肝炎和中毒性心肌炎。

They could be seen only in children over three years old . 3 . The incidence of complications is high in children with typhoid fever . Toxic hepatitis and toxic myocarditis happen in relatively high frequencies .

并发症中的肠出血占12%，中毒性肝炎占5.9%，中毒性心肌炎占3.4%。

There were intestinal hemorrhage ( 12 % ), toxic hepatitis ( 5.9 % ) and toxic myocarditis ( 3.4 % ) as complications .