中毒剂量
- 名toxic dose;poisonous dose
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结果碘化油对肝、脾、肺、肾等多个脏器有毒性反应,中毒剂量小于0.38ml/kg剂量,1.5ml/kg剂量可导致动物在24h内死亡。
Results Lipiodol showed toxicity to the liver , spleen , lung and kidney etc. Toxic dose was less than 0.38ml / kg , a dose of 1.5mL/kg could cause death in 24h .
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方法胆碱酯酶抑制剂氧化乐果在30mg·kg-1po中毒剂量(1.2个致死剂量,1.2LD)下,可诱发全部的受试昆明种小鼠死亡。
Methods After administered with cholinesterase inhibitor omethoate at the toxic dose of 30mg · kg - 1 po ( 1.2LD ), all the mice were dead .
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结论(1)以全血ChE活力测定为基础的混血法,在中毒剂量范围内可较好地反映血中残余有机磷的粗略水平;
Conclusion The monitoring of blood ChE by " mixed blood method " may reflect the general level of the blood residual OP within the range of exposure dose .
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静脉注射中毒剂量奎尼丁建立QTU间期延长综合征动物模型,应用接触电极导管记录犬左室心内膜单相动作电位(MM),以研究早期后除极(EAD)与U波的关系。
To investigate the relationship between early afterdepolarization ( EAD ) and abnormal U wave , the monophasic action potential ( MAP ) was recorded by endocardial contact electrode in 11 anesthetized dogs with quinidine-induced long QT syndrome .
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用SD大鼠研究了赛特铂配合物药物材料口服给药的长期毒性,结果表明基本无毒剂量为10mg/kg,20mg/kg是低中毒剂量。
Researches have been done on the long-term toxicity of oral administration of Satraplatin by using the SD rats , and the results showed that the innocuity dose is 10mg / kg , and 20mg / kg is the low-grade toxicity dose .
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中毒剂量(一次150&200毫克/干克)则引起呕吐、食少、心电图S-T(ⅡⅢ)压低、T波平坦、血压下降、呼吸抑制,最后死亡。
Toxic doses ( 150 200 mg / kg ) elicited vomiting , reduction of food intake , hypotension , depression of S T segment and flattening of T wave in the EKG , respiratory embarrassment , and finally death .
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复方酒剂中乌头碱含量的测定及其中毒剂量的研究
Determination of Aconitine in Medicinal Wine and Its Dosage of Aconitine Poisoning
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中毒剂量锌对大鼠小肠粘膜超微结构的影响
Effects of zinc poisoning on the ultrastructure of intestinal mucosa
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维生素D中毒剂量的动物实验研究
A study on vitamin D toxic dosage in rabbits
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大鼠体内中毒剂量氨茶碱的时辰药物动力学
Chronopharmacokinetics of aminophylline at a toxic dose in rats
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中毒剂量可产生发热作用。
Toxic doses can produce a febrile effect .
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兔尿素的中毒剂量
Study on Urea Toxic Dose in Rabbit
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此时,中毒剂量和致死剂量之间的差距缩短。
As this occurs , the margin between an intoxicating dosage and fatal dosage becomes smaller .
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结果地高辛的有效剂量和血药浓度以及中毒剂量和血药浓度变异很大。
Result There has a great variation in the effective dosage , serum concentration in the cases .
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肝毒剂中毒剂量;
Dose of liver toxicosis ;
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中毒剂量谷氨酸引起大脑皮质神经细胞的钙振荡及其机制探讨
Ca ~ ( 2 + ) oscillation of cerebral cortical neurons induced by glutamate of toxic dose and its mechanism
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大鼠静注中毒剂量苯妥英钠后唾液与血浆及组织中药物浓度相关性研究
Correlations of Phenytoin Concentrations among Saliva and Plasma or Tissues after iv Administration of Toxic Dose of Phenytoin to Rats
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结论连续两周中毒剂量的哇巴因可以成功的构建慢性洋地黄中毒模型。
Conclution : The animal model of chronical digitalis intoxication can be constructed with continous injection ouabain intraperitoneally for two weeks .
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结果表明,治疗剂量庆大霉素对肾脏具有损伤作用,中毒剂量损伤明显加重。
The results showed that gentamycin has harm to kidney in therapeutic dose and more serious harm was found in toxic dose .
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目的:研究中毒剂量与治疗剂量克仑特罗在兔体内的组织分布,分析比较两者差异。
OBJECTIVE To investigate the tissue distribution of clenbuterol at toxic dosage in rabbits , to assess its difference between toxic and therapeutic dosages .
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目的研究克仑特罗在引起不良反应的大剂量下兔体内的药动学,探讨中毒剂量与治疗剂量的药动学参数存在的差异。
OBJECTIVE To investigate the pharmacokinetic parameters of clenbuterol at toxic dosage , to assess its difference of pharmacokinetic parameters between toxic and therapeutic dosages .
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分别测定治疗剂量、中毒剂量、致死剂量组小鼠在用药一段时间后的肝肾功能,并进行组织病理学检查。
Hepatic and renal functions , and tissue biopsy were measured in rats with therapeutic , toxic and lethiferous dose treatment after a period of time .
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试验结果表明:1.铜对肉用乌骨鸡的一般性中毒剂量为600mg/kg饲料。
The experiment results indicated that : 1 . The dosage of copper poisoning in black bone broiler was 600 mg / kg in meal diet .
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得到乌骨鸡的铜中毒剂量后,采用二因子多水平随机化实验设计来研究日粮硼、锰对铜中毒乌骨鸡的影响。
Then , 440 day-old healthy broilers were contacted with 2 × 2 factorial design to study the effect of inorganic boron and manganese anti black bone broiler copper poisoning .
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由于口服或静注胺碘酮后,吸收、消除等药物代谢的个体差异较大以及治疗剂量和中毒剂量十分接近。因此需要研究发展一种快速测定及过程监测的方法。
Because of comparatively large individual variation of its absorption and elimination after oral administration or intravenous injection , it is necessary to develop a fast and on line method for amiodarone determination .
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茶碱类药物治疗剂量和中毒剂量较接近,临床应用受到一定限制,但其药理作用广泛仍有潜在的研究前景。
As the therapeutic dose and the toxic dose of theoclears were quite similar , the clinical use of which should be restricted to some extent , yet the prospect on the study of their extensive pharmacological actions is potential .
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结果醋氨酚中毒剂量与Fas/FasL表达之间关系密切(P<001),醋氨酚剂量越大,Fas/FasL表达越强。
Results We found that there was a close relationship between expression of Fas / Fas ligand and dose of acetaminophen ( P < 0 01 ): the higher the dose of acetaminophen , the stronger Fas / FasL expression .
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在不致中毒的剂量下,对小鼠肉瘤180,肉瘤AK,黑色素瘤Me则无明显抑制作用。
However , N-F has no marked effect on other mice tumors including sarcoma 180 , sarcoma AK and melanoma Me .
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目的明确光气急性中毒的剂量-反应关系与其半数致死浓度(LC50),建立光气中毒肺水肿动物模型,为进一步研究光气损伤机制及防治手段奠定基础。
Objective To determine dose-response relationship of phosgene poisoning and establish pulmonary edema animal model , so as to provide basis for further study on lung injury and treatment of phosgene .
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亚中毒阈剂量毒死蜱的神经发育毒性
Developmental neurotoxicity of chlorpyrifos at subthreshold dose of overt systemic toxicity