补体激活

结论：细胞粘附分子和补体激活成分的相互作用参与了MOF的发生和发展，且与病情严重程度和预后有密切关系。

Conclusions : The interaction of cell adhesion molecules and composition of complement activation appears to be involved in the development of postinjury MOF , and it might be closely related to the severity of illness and prognosis .

补体激活造是炎症反应性疾病的病理反应之一。

Complement activation is the basic pathological reaction in inflammatory diseases .

旁路活化补体激活内皮细胞表达趋化因子及其NF-kB调控作用的实验研究

Experimental study on the influence of bypass-activated complement on endothelial cells to express IL-8 and MCP-1

眼镜蛇毒因子（CVF）是一种具有补体激活活性的糖蛋白。

Cobra venom factor ( CVF ) is a nontoxic glycoprotein present in cobra venom with strong complement-activating activity through the alternative pathway .

目的：研究补体激活对男性冠心病（CHD）及健康成年人血小板的作用及抗CD59对该作用的影响。

Objectives : To study the reactions of human platelet to active complement and the effects of anti-CD59 on platelet activation induced by complement in patients with coronary heart disease ( CHD ) and healthy adult males .

CR1是唯一既对经典、替代及植物凝集素（MBL）3个补体激活途径的，对C3/C5转化酶拥有衰变加速活性，又有辅助1因子裂解C3b和C4b作用的补体调节蛋白。

CR1 has activation to the three pathways of complement activation to enhance decay of the C3 / C5 convertase and helps factor 1 to split C3b and C4b .

结论：补体激活剂CVF能诱导大鼠血小板聚集、ATP释放，增加血小板表面凝血酶原酶活性，其激活血小板的作用与血小板表面纤维蛋白原受体及血小板内游离钙升高、cAMP下降有关。

CONCLUSION : Complement activator CVF induced platelet aggregation and ATP release , and increased prothrombinase activity on platelet surface . These actions were dependent on fibrinogen receptors on the platelet surface , elevation in intracellular free calcium ion , and reduction in cAMP .

因此，正常生理水平的CRP不能诱导内皮细胞的炎症损伤，但是在有脂质代谢紊乱的条件下，能够介导E-LDL参与内皮损伤，补体激活，从而触发动脉粥样硬化早期形成的过程。

CRP can connect E-LDL to endothelial cells , thus can induce deposition of lipid in intima and activate complement . Therefore , CRP could mediate E-LDL participating in the early stage of atherogenesis .

tPA除了参与体内溶血和凝血的平衡调控外，还与其它一些重要的生理与病理过程密切相关，如组织再造、细胞迁移、排卵、补体激活、激肽产生、肿瘤侵袭等。

In addition to revolving in regulating the balance of hemolysis and coagulation , it is closely concerned to some important physiological and pathological courses , such as tissue reforming , cell translocation , ovulation , activated peptide production , tumor invasion and so on .

结论温冷双抗体型AIHA是一种女性多见、原发性为主、与抗体种类和温幅及补体激活相关、复发率较高的溶血性疾病，联合免疫抑制治疗效果较好。

Conclusions AIHA with both warm and cold autoantibodies is related with the type and thermal amplitude of the autoantibody and the activation of complement . It can be treated effectively with combined immunosuppressive therapy , but the relapse rate is high .

方法：通过犬和人空白血清与药物的孵育实验，检测补体激活通路的指标，并通过EGTA/Mg2+、sCR1等补体通路的阻断剂对药物激活补体的机制进行研究。

Methods : The drugs were maxed with the blank serum of dogs and humans , the hematological index in the sera were detected by ELISA . Through the complement blocking agents , EGTA / Mg2 + , sCRl , the mechanism of complement activation was researched .

体外循环患者血清补体激活及途径的临床研究

Clinical study on serum complement activation in patients undergoing cardiopulmonary bypass

结论急性缺血性脑血管疾病早期存在短暂的补体激活。

Conclusions Transitory systemic complement activation takes place after acute ischemic stroke .

不稳定型心绞痛病人血管性血友病因子与可溶性补体激活产物的变化

Changes of von Willebrand factor and complement component in patients with unastable angina

脑缺血再灌注中补体激活的实验研究

Experimental Investigation of Complement Activation in Cerebral Ischemia-Reperfusion

肾小管间质损伤中补体激活的意义

Activation of complement in renal tubulointerstitial damage

急性心肌梗死病人补体激活与心肌缺血损伤的关系

The relation between complement activation and myocardial ischemic damage in the patients with actue myocardial infarction

急性心肌梗塞病人细胞粘附分子与补体激活成分的动态变化

Changes in cell adhesion molecules and composition of complement activation in patients with acute myocardial infarction

结论：该模型适用于补体激活相关类过敏反应的补体通路的检测。

Conclusions : This model is suitable to analyse the complement pathways of the anaphylactoid reactions .

结论粘附因子和补体激活片段在哮喘的发病中可能起了一定的作用。

Conclusion Adhesion molecular system and complement activated fragment may play an important role in asthma .

天花粉蛋白对肥大细胞脱颗粒和组胺释放的影响及其与补体激活的关系

Effect of trichosanthin on mast cell degranulation and histamine release and its relationship with complement activation

眼镜蛇毒因子抑制补体激活对创伤失血性休克大鼠血浆内毒素含量的影响

Influence on the concentration of plasma endotoxin by inhibition of complement activation in traumatic hemorrhagic shock rats

分为两大组，分别为空白对照和补体激活产物处理组。

The main groups were as follows : the blank control group and complement activated product group .

一个与补体激活能力相关的丝氨酸酯酶成分也被发现存在于这个复合物中。

A serine protease component being responsible to the ability of complement activation were also found in this complex .

创伤后多脏器功能衰竭患者细胞粘附分子和补体激活成分水平的变化及意义

The significance of changes in cell adhesion molecules and composition of complement activation in trauma patients with multiple organ failure

目的探讨长期吸入糖皮质激素对哮喘患儿粘附因子系统与补体激活片段的影响。

Objective To research the influence of long-term inhaled glucocorticoids on adhesion molecular system and complement activated fragment of bronchial asthmatic children .

近年来，肝素的抗炎、抗补体激活等非抗凝活性也得到关注，但尚未得到应用。

Recently , other non-anticoagulant activities of heparin , such as anti-inflammatory and anti-complement activation , have been concerned but not utilized .

其中病毒抗原变异逃逸抗体的中和和病毒干扰补体激活的关键环节来抑制宿主的抗病毒状态是病毒拮抗机体体液免疫反应的主要途径。

Virus is capable of evading immune attack of humoral response by antigenic variation and interfering , or inhibiting activities mediated by complements .

除了在宿主防御中起到关键作用之外，补体激活还在许多病理情况下引起炎症反应和免疫应答。

Besides a critical role in innate host defence , complement activation contributes to inflammatory and immunological responses in a number of pathological conditions .

目的探讨慢性心力衰竭（心衰）患者是否存在补体激活以及补体激活与心衰患者预后的关系。

Objective To determine whether the complement system is activated and its relation to clinical outcome in patients with congestive heart failure ( CHF ) .