旁路途径

异位性皮炎皮损的大片段DNA微点阵分析显示旁路途径中表皮分化基因簇过表达以及角质层保护性基因表达缺乏

Large-scale DNA microarray analysis of atopic skin lesions shows overexpression of an epidermal differentiation gene cluster in the alternative pathway and lack of protective gene expression in the cornified envelope

B因子缺乏的人血清（阻断旁路途径）仅溶42±10%的猪血管内皮细胞（P＜0.01）。

When the alternative pathway was selectively inhibited by using factor B deficient human serum which could only lyse 42 ± 10 % of porcine endothelial cells ( P < 0 01 versus normal serum ) .

烧伤后血清总补体和旁路途径溶血活性及补体C3的动态变化

Changes of Serum Complement Hemolytic Activities and C3 Level Following Thermal Injury

而且，通过这些位点活化的AT1-R，可能激活的是G蛋白非依赖的旁路途径，并最终改变心肌细胞的生物学性状。

These activated domains might finally change the biological characters of cardiomyocytes through G protein independent pathway .

补体的激活过程依据其起始顺序的不同，可分为三条途径：经典途径、MBL途径和旁路途径。

Complement is activated by three pathways : the classical pathway , the alternative pathway and the lectin pathway .

注射7d后观测外周血和脾脏中淋巴细胞ANAE阳性率、血清旁路途径溶血活性、血清溶菌活性。

After 7 days , we measured α - naphthyl acetate esterase ( ANAE ) activity in peripheral blood and spleen , hemolytic activity and bacteriolytic activity .

补体成分3（Complementcomponent3，C3）是补体系统的中枢，补体激活的3条途径即经典途径、旁路途径和凝集素途径都要通过激活C3才得以实现。

The third component of complement ( C3 ) plays a central role . C3 supports the activation of all the three pathways of complement activation , i.e. the classical , alternative , and lectin pathways .

与对照组相比，C0组外周血T淋巴细胞ANAE阳性率和血清旁路途径溶血活性均有显著提高，脾脏T淋巴细胞和血清溶菌活性没有显著变化。

C0 group showed higher ANAE positivity in blood and hemolytic activity than the control , but showed no significant difference in bacteriolytic and ANAE activity in spleen .

为探讨异种（猪／人）超急性排斥时补体旁路途径的作用机制。

To study the role of alternative complement pathway activation in porcine to human xenograft hyperacute rejection .

将经典途径及旁路途径缺陷的人血清等体积混合，其细胞毒作用恢复正常。

Mixing serum with deficient classical pathway and serum with deficient alternative pathway restored the cytotoxicity to normal levels .

通过选择性阻断补体两条激活途径，发现这种芽孢杀灭依赖补体系统，补体经典和旁路途径均参与作用，但经典途径起主要作用。

By selectively blocking the complement activation pathways , it was found that both the classical and alternative complement activation pathways of NRS took part in the killing of the spores . But the classical pathway was mainly responsible .