正链

复发见于治疗前后PBMCs中正链HCVRNA持续阳性的患者。

The relapse occurred in patients whose plus strand HCV RNA in PBMCs remained positive before and after treatment .

在同例肝（癌）组织中，若负链HCVRNA阳性，则其信号强度与正链基因无明显差别；

In the cancer tissues of a same case , if minus strand RNA of HCV was positive , its signal intension had no significant difference from that of HCV plus strand RNA .

正链RNA病毒基因组感染性克隆研究进展

Research Advancements of Genomic Infectious cDNA Clone of Positive-Strand RNA Virus

正链RNA病毒感染性克隆的构建策略及影响因素

Construction strategy and influence factors of positive-strand RNA virus infectious clone

活细胞内脊髓灰质炎病毒正链RNA可视化研究

Visualization of Poliovirus Plus-strand RNA in Living Host Cells

单股正链RNA病毒基因组3′非编码区的高级结构与功能研究进展

The Progress in 3 ′ Untranslated Region of Single Strand Plus RNA Virus

正链RNA病毒复制蛋白的分子生物学研究进展

Progress in the molecular biological studies on replication protein of plus-strand RNA virus

从带烟草花叶病毒外壳蛋白亚基因组启动子的负链RNA产生正链RNA

Positive-strand produced from negative-strand RNA containing coat protein subgenomic promoter of tobacco mosaic virus

但其反向遗传学的发展则远远落后于正链或负链RNA病毒。

However , reverse genetics of dsRNA viruses lag behind the positive-strand or minus-strand RNA viruses .

星状病毒属单独的星状病毒科，星状病毒属，无衣壳单股正链RNA病毒。

Astrovirus is a non-capsid single-strand sensitive RNA virus and a family of Astroviridae and Astrovirus .

在病毒感染后的不同时间，脊髓灰质炎病毒正链RNA在寄主活细胞内展示不同的分布模式。

Poliovirus plus-strand RNA was observed to display different distribution patterns in living Vero cells at different post-infection time .

许多正链RNA病毒是严重危害人类健康的病原体，是造成经济植物动物死亡的致病因子。

Many plus-strand RNA viruses are the causative agents of some highly contagious diseases in human , animal and plant .

抗HCV阳性患者体液中正链和负链HCVRNA的检测及意义

Detection and significance of plus-and minus HCV RNA in body fluids of anti-HCV positive patients chain of Immunology

分别建立正链和负链HCVRNA的巢式荧光定量RT-PCR方法并分析敏感性和特异性。

A nested fluorescence quantitative RT-PCR method to detect positive - and negative - strands HCV RNA is established .

丙肝病毒是一种正链RNA病毒，它是导致人类肝脏疾病的重要因素。

Hepatitis C virus ( HCV ), a positive single-stranded RNA virus , is a major cause of liver disease in humans .

CSFV是有囊膜的单股正链RNA病毒，基因组长约12.3kb。

CSFV is an enveloped RNA virus with its genome size of approximately 12.3 kb .

冠状病毒是一类球形、有包膜的病毒，基因组为长约30kb的单股正链RNA，主要引起人和动物的呼吸道与肠道疾病。

The coronaviruses are a diverse group of large , enveloped viruses that cause respiratory and enteric diseases in humans and other animals .

流感病毒是一种有高度传染性的正链RNA病毒，能对人的上呼吸道和下呼吸道上皮细胞进行感染。

Influenza A virus ( IAV ) is a highly infectious RNA virus , which can infect the upper and lower airway epidermic cells .

小RNA病毒科属于正链RNA病毒，该科各属病毒基因组结构和基因表达机制具有保守性。

The viruses of Picornaviridae are positive-strand RNA viruses , the genome organization and mechanisms of gene expression belong to highly conserved among them .

4例患者中，1例患者细胞中连续2个月检测到HCVRNA正链，HCVRNA负链间断出现。

HCV RNA plus strain was detected in one patient 's PBMC continuously for 2 months , and minus strain was detected intermittently .

登革病毒是单股正链RNA病毒，基因组全长约11Kb，含有单一开放读码框架。

The genome of dengue virus is a single-strand positive sense RNA of approximately 11 Kb in length , containing a single open reading frame .

口蹄疫病毒（Foot-and-mouthdiseasevirus，FMDV）属于小RNA病毒科口蹄疫病毒属，为大约8500nt的单股正链RNA病毒。

Foot-and-mouth disease virus ( FMDV ), is a positive stranded RNA virus that belongs to the Aphthovirus genus of the Picornaviridae family .

运用长时间活细胞荧光影像捕获和荧光漂白恢复等技术手段，研究了脊髓灰质炎病毒正链RNA在活细胞内的行为特征。

By using living cell imaging , time-lapse monitoring and FRAP technique , the intracellular behavior of poliovirus plus-strand RNA was studied in living host cells .

丙型肝炎病毒（HepatitisCVirus，HCV）为单股正链RNA病毒，直径40～60nm，有包膜。

Hepatitis C virus ( hepatitis C , HCV ) is an enveloped , positive single-stranded RNA virus , with the diameter of 40 ~ 60 nm .

通过对外周血单个核细胞（PBMC）中正链及负链HCVRNA的检测来探讨HCV在PBMC中的复制与丙肝慢性化及复发的关系。

To study the relation of chronic hepatitis C and relapse with HCV RNA in sera and peripheral blood mononuclear cells ( PBMC ) .

而正链RNA病毒的反向遗传操作系统在病毒复制、致病机制研究，抗病毒药物筛选和新型疫苗、导向载体制备等方面是一个极其有用的工具。

Positive-strand RNA virus reverse genetics system is an useful tool in viral replication , pathogenesis research , screening antiviral drugs and new vaccines , vector-oriented areas such as the preparation .

脊髓灰质炎病毒正链RNA特征性的移位和重排需要寄主细胞完整的微管网络，破坏微管网络可以改变RNA的分布模式。

The translocation and rearrangement of poliovirus plus-strand RNA requires intact microtubule network of the host cell . Disruption of microtubules could alter the characteristic distribution patterns of poliovirus plus-strand RNA .

正链RNA只含一个长的开放阅读框，编码一个由1146个氨基酸组成的蛋白，推测其分子量为131.8kD。

Computer analysis indicated tha the coding strand contained only one open reading frame ( ORF ) encoding for a polypeptide of 1146 amino acids with predicted molecular mass 131 . 8 kD .

同时用核酸酶保护法对其中7例肝炎患者的肝组织做TTV正链的检测。

A hybridization / nuclease protection assay was used to detect positive-strand TTV fragment from the liver specimens of the 7 patients .

Lamivudine是一种目前广泛应用的抗病毒药物，它可同时抑制反转录酶和DNA依赖性DNA聚合酶的活性，从而同时阻断HBV负链和正链DNA的合成。

Lamivudine inhibits viral replication at the level of progeny DNA synthesis . Specifically , its incorporation into nascent DNA causes chain termination . This applies both to the reverse transcriptase-and the DNA-dependent DNA polymerase activity of the virus .