正调控

CyclinE属于G1期的正调控因子，结合并激活CDK，启动DNA合成，从而实现G1/S期转化。

Cyclin E is one of positive regulation factors in G1 period . It combines CDK and promotes the DNA synthesis to realize the switch from Gl to S period .

应用萤光素酶报告基因系统证明了本实验所鉴定的NF-κB反应元件是nNOS1f启动子中一个强大的正调控元件，同时它在TSA引起的nNOS1f启动子的转录激活中发挥重要作用。

Results of luciferase assay showed the identified NF - κ B responsive element acted as a powerful positive regulation element and took an important part in TSA-induced activation of nNOS 1f promoter . 7 .

人Toll样受体4基因5′正调控区的鉴定

Identification of a positively 5'regulatory region in human Toll like receptor 4 gene

早期光诱导蛋白（EarlyLight-inducedproteinELIP）基因是20世纪80年代初研究发现的受光正调控的基因。

Early light-induced protein ( ELIP ) is positively light-regulated gene found at the beginning of the 1980s .

Bad（Bcl-2antagonistofcelldeath）是Bcl-2蛋白家族的成员之一，是细胞凋亡的正调控因子，正常情况下定位于细胞质中。

Bad ( Bcl-2 antagonist of cell death ), a member of the Bcl-2 protein family , is a positive regulator of cell death and is localized in the cytoplasm under physiological conditions .

结论CD31分子广泛分布于脐血造血细胞，并对脐血造血细胞有正调控作用。

Conclusion CD31 molecule could express widely onthe cord blood hematopoietic cells and positively regulate those cells growth .

而长程协同作用的寡核苷酸对的平均最近距离集中在250￣400bp，并且在多数寡核苷酸对中，位于上游区的寡核苷酸是GC丰富的正调控元件。

For the long-range synergistic oligonucleotide pairs , the average nearest distances were within the range from 250 bp to 400 bp and majority of the oligonucleotides located upstream regions were GC-rich positive regulatory elements .

同时，发现植物在低温胁迫下，显著诱导参与钙／钙调素介导的信号转导、ABA体内平衡和运输与抗氧化防御系统的一系列基因，通过正调控来增加杨树的抗寒性。

A series of genes involved in calcium / calmodulin-mediated signal transduction , ABA homeostasis and transport and antioxidant defense systems were significantly induced under chilling stress suggesting might play a positive regulator in enhanced low temperature tolerance of poplar .

结果经过对与饮食相关的诸因素进行Logistic单因素分析，每次喝酒量的多少，家人对饮食疗法执行的支持情况，性别等三项指标，其OR值均大于1，是正调控因素。

Results Analyzing the relation among diet and close factors with logistic single factor , the amount of drinking alcohol each time , the support of the family for the dietotherapy and sex ect , their OR value > 1 , it is positive regulate factor .

本人设计并合成了探针，以小鼠为模式动物，提取正常及心肌肥大的小鼠心脏RNA，用RT-PCR的方法进行分析，得出小鼠Pop1基因对心肌肥大起正调控作用的结论。

I have designed and synthesized the probe , using mouse as model animal , extracted RNA from the hearts of normal and cardiac hypertrophy mice , then analyzed by RT-PCR method . The result shows that mouse Popl gene can modulate cardiac hypertrophy positively .

这些结果表明MKP-1通过正调控JNK-BAD信号通路来调节内质网应激诱导细胞凋亡。

These results suggest that MKP-1 plays a pivotal role in ER stress-induced cell apoptosis through regulating JNK-BAD signalling .

血小板生长因子（TPO）是巨核细胞系唯一的特异性生理性正调控因子。它可诱导造血干、祖细胞向巨核细胞系分化，促进巨核细胞的发育成熟及血小板的生成和释放。

Thrombopoietin ( TPO ) is a normal physiological hematopoiesis factor which is able to stimulate the hematopoietic progenitor cells to proliferate and differentiate into megakaryocytes and to induce the production and release of platelets .

NK细胞可能通过直接与造血干细胞相互作用或改善造血微环境等促进内源性造血功能，从而发挥对造血的正调控作用。提示NK细胞在小鼠造血功能的平衡维持中起重要作用。

NK cells might exert their positive regulating effect on hemopoiesis through direct contact with hemopoietic stem cells or by purifying and improving the hemopoietic microenviroment , implicating that NK cells might play an important role in maintaining the balance of hemopoietic function in mice .

结论本实验已成功地克隆了人肺癌细胞NHE1基因调控序列中正调控序列片段。

Conclusion The positive regulatory fragment of NHE 1 gene from human lung cancer cells was successfully cloned .

结论Wnt-1基因在全反式维甲酸诱导人胚胎神经干细胞分化为神经元的过程中起正调控作用，Wnt-1基因与神经元的分化关系密切。

Conclusions There are the important role for the expression of Wnt-1 gene during the human embryonic neural stem cells differentiated into neurons , the gene plays the positive-regulation role .

正调控型和负调控型bHLH转录因子之间的彼此调控，共同调控着神经干细胞的分化并且决定着其分化方向。

The positive regulator and negative regulator type transcription bHLH transcription factors regulated and controlled each other , which together controlled the differentiation of NSC and determined the direction of their differentiation .

所以microRNA的调控符合进化的需要。（2）MicroRNA对细胞周期的正调控机制研究。现有认识来看，一般认为MicroRNA是与它的目标基因配对后通过抑制其表达来行使调控的。

So the emergence of microRNA-regulation meets the requirements of evolution . ( 2 ) The mechanism of microRNA ' positive regulation on cell cycle ; Now it is believed that microRNAs function through base-paring with its target genes to repress its expression .

美伐他汀生物合成基因簇已经被鉴定，受到途径特异性转录激活因子mlcR的正调控。但是，在桔青霉中，还没有发现控制美伐他汀生物合成的全局性调控因子。

Biosynthesis in P. citrinum has been identified . Among them , mlcR is a pathway-specific zinc cluster transcriptional activator of the mevastatin biosynthetic genes .

在全基因组测序和芯片分析的基础上，为进一步探讨和研究A1501固氮基因的转录调控机制，本研究开展了正调控蛋白NifA一个关键位点的定点突变分析。

For further exploring and studying the expression and regulation of nif genes , we carried out site-directed mutagenesis on a crucial tyrosine residue of the positive regulator protein NifA .

目的克隆人肺癌细胞Na+/H+交换泵1（NHE1）基因上游正调控序列部分，为进一步将该片段导入肺癌细胞株，竞争性结合转录因子，达到抑制细胞内NHE1基因的表达奠定基础。

Objective To clone the partial positive regulatory fragment of Na + / H + exchanger 1 ( NHE 1 ) gene from human lung cancer cells .

结论发现GCLC基因其中2个正调控区域（-403~-111bp与-705~-613bp）和1个负调控区域（-745~-705bp），其中负调控区域-745~-705bp上的E-box元件通过与USF结合介导GCLC基因的负性表达调控。

Conclusions Two positive regulatory regions and one negative regulatory region of GCLC gene are found . The E-box element within the negative regulatory region mediates the negative expression regulation of GCLC gene by the binding with transcriptional factors USF1 / USF2 .

沙利度胺对人外周血单个核细胞免疫正调控作用

Positive Immunoregulation of Thalidomide on Human Peripheral Blood Mononuclear Cell Cultures

细胞周期的调控由细胞周期调控蛋白完成，按其功能分为正调控蛋白和负调控（抑制）蛋白。

The cell cycle is controlled by positive and negative regulation proteins .

酵母基因上游序列中潜在的转录正调控位点分析

Analysis of Potential Sites in Upstream Regions for Positive Transcriptional Regulation of Yeast Gene

酵母基因中转录正调控内含子序列特征的统计分析

Statistical Analysis of Sequence Features of Introns With Positive Transcriptional Regulation in Yeast Genes

该研究发现了一个对种子大小有正调控作用的基因，为深入研究种子大小决定的机理提供了重要资料。

Our data provided important information to further study the mechanism of seed size determination .

目的利用基因工程的方法，建立受胰岛素负调控、地塞米松正调控的人工β细胞株。

Objective To engineer an artificial β cell line by which insulin production is down regulated by insulin and up regulated by dexamethasone .

而分枝正调控基因主要涉及：细胞分裂控制，糖基和糖苷转移，糖转运，转录水平调控和翻译水平调控等。

Positive regulatory genes are mostly involved in cell division control , the transfer of glycosyl , sugar transport , transcriptional regulation and translation regulation .

在柱花草和大麦中，硫转运蛋白基因表达调控包括植物体内硫水平的负调控和O-乙酰丝氨酸的正调控两种方式。

In the Stylosanthes hamata and barley , there have two regulation patterns : a negative feedback by sulphur level in plant and a positive feedback by O-acetylserine .

正常的造血过程有赖于各种调控因素之间的平衡，正调控因素过多或负调控因素过少，均会造成造血失控。

The normal regulation of hematopoiesis depends on the balance among various factors , regulatory factors are too many or negative regulatory factors are too few will cause out of control of hematopoiesis .