天毒
天毒-
经口给药14天，毒作用阈值为3.21g／kg（临床用量25倍），靶器官为肝。
In 14 day repeated dosing test in rats , toxicity threshold of Niuhuang Jiedu Pian was 3 . 21 g / kg ( equel to 25 times of clinical dose ) and the target organ was liver .
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用改良Fries培养液培养的菌株在第10天出现生长高峰，在第12天产毒最多。
The isolate growth peak appeared on the 10 th day after cultivation and the most toxin was produced on the 12 th day .