基因治疗

其中基因治疗的靶向性是值得密切关注的问题之一。

The targeting of gene therapy has been paid close attention .

血友病B基因治疗临床试验的安全性研究

Safety assessments required for animal test and preclinical trial of hemophilia B gene therapy

基因治疗新策略&酶性DNA的设计和应用

New strategy in the gene therapy : design and application of catalytic DNA

CT导引下肝细胞生长因子基因治疗脑缺血的实验研究

The experimental study of CT-guided hepatocyte growth factor gene therapy for cerebral ischemic diseases

非小细胞肺癌p53基因治疗的循证医学评价

Evidence-based Appraisal of p53 Gene Therapy for Non-Small Cell Lung Cancer

腺病毒介导胞嘧啶脱氨酶（CD）基因治疗胰腺癌的实验研究

Adenovirus-Mediated Cytosine Deaminase ( CD ) Gene Transfer in the Treatment of Pancreatic Cancer

腺病毒介导th基因治疗帕金森病

Adenovirus-Mediated th Gene Therapy of Parkinson 's Disease in Experimental Rat Model

目的：探讨白细胞介素7裸DNA质粒用于小鼠肿瘤基因治疗的可行性。

Objective : To investigate the possibility of gene therapy with naked plasmid encoding interleukin 7 ( IL 7 ) .

利用bcl-2基因治疗慢性充血性心力衰竭的实验研究

The Experimental Studies on Treating Chronic Congestive Heart Failure Using bcl-2 Gene

AIDS基因治疗策略

Gene Therapy Strategies for AIDS

目的研究仙台病毒载体复制序列对未成熟树突状细胞（Dendriticcells，DC）蛋白质表达的影响，为联合运用二者进行基因治疗提供依据。

Objective To investigate the protein change in immature dendritic cells ( DC ) exposed to sendai virus replication sequence .

结论腺病毒介导的p53基因治疗能有效控制肝癌的生长。

Conclusions Replication-deficient adenoviral vector expressing WT-p53 may be useful for gene therapy of HCC .

IL-2和IL-12联合基因治疗小鼠肝癌的实验研究

Gene therapy with IL-2 and IL-12 for murine hepatocellular carcinoma

自杀基因治疗鼠C6脑胶质瘤模型的动态MRI研究

The Therapeutic Effect of Suicide Gene on Rat C6 Glioma Model Dynamic Observation with HR MRI

目的探讨乙型肝炎病毒（HBV）作为肝靶向性基因治疗载体的可能性。

Objective To evaluate the possibility of hepatitis B virus ( HBV ) as a vector in liver-targeting gene therapy .

HIVVpr蛋白应用于特异性肝癌基因治疗的研究

Study on the Application of HIV Vpr to Specific Hepatoma Gene Therapy

用COX一2启动子构建的重组载体需经合理修饰后才可用于卵巢癌的基因治疗。

With proper modification , COX-2 promoter is useful in gene therapy of ovarian cancers .

目的初步观察动脉灌注p53基因治疗晚期肝癌的疗效。

Objective To preliminarily investigate curative effect of hepatic arterial perfusion of p53 gene in the therapy of advanced hepatocellular carcinoma .

将来可能包括基因治疗，MMP调节剂和抑制剂，PDT。

Future could include gene therapy , MMP regulators and inhibitors , PDT .

这些发现使这套DNA载体介导的RNA干扰表达系统能够在功能基因组研究方面广泛发挥作用，并有望成为基因治疗大家族中重要的一员。

These findings highlight the general utility of this DNA vector-based RNAi technology in suppression gene suppression gene expression in mammalian cells and the applications in gene therapy .

细胞色素P450与肿瘤的基因治疗

Cytochrome P450 and Cancer Gene Therapy

针对VEGF的抗肿瘤血管生成的治疗已取得了很大进展，包括应用VEGF抑制剂、腺病毒介导的基因治疗等。

The anti-angiogenesis treatments aimed at VEGF , including the applications of VEGF inhibitor and gene therapy of adenovirus medium , had got great progress .

联合反义缺氧诱导因子-1α与B7-1基因治疗肿瘤的实验研究

Antisense hypoxia inducible factor-1 α and B7-1 combination gene therapy for mouse lymphoma

目的构建pcmGMCSF重组质粒载体，为mGMCSF基因治疗肿瘤的研究奠定基础。

Objective To construct recombiant plasmid pc-mGM-CSF and lay a primary foundation for further study of mGM-CSF gene therapy for tumors .

目的构建人白介素24（hIL24）的腺病毒载体，获得hIL24重组腺病毒子，为hIL24进行肿瘤的基因治疗奠定基础。

Objective The recombinant adenovirus vector of hIL-24 was constructed for carcinoma gene therapy .

基因治疗有望成为治疗AITD的一种新途径。

Gene therapy is a new and promising way to cure AITD .

结论：1.Survivin在k562细胞中高表达，可作为白血病基因治疗的靶点；

Conclusions 1 . The protein level of survivin in k562 cells is high . Survivin may be a new target of leukemia gene therapy .

深入了解并阐明HSP的发病机制对寻求新的免疫学和未来的基因治疗十分重要。

A deeper understanding and illustration of HSP 's pathogenesis are very important for searching new immunology and future gene therapy .

本研究为IL-15为基础的肿瘤免疫基因治疗的临床应用提供了实验依据。

Therefore , this study provides evidence for the clinical application of IL-15 base gene therapy .

结论靶向EGFR的siRNA表达载体可以特异性地抑制EGFR的表达，可以成为胶质瘤靶向性EGFR基因治疗的一种新策略。

Conclusion The siRNA expression constructs targeting EGFR could specifically inhibit EGFR expression , and should be a new strategy in glioma gene therapy targeting EGFR .