固缩

30d时，细胞核固缩，细胞消失；恶性食管狭窄的姑息治疗&附26例报告

The nuclei underwent pyknosis . Palliative treatment of the malignant esophagostenosis

结果HBO组动物心肌细胞线粒体肿胀、细胞核固缩、核周膜性空泡；

Results In the HBO group , the myocardial cells showed mitochondrial swelling , nucleus pyknosis and peri nucleus membranous vacuoles ;

结果：吲哚美辛诱导野生型p53转染的wtp53/SW480细胞凋亡，出现形态学改变：即细胞核固缩、裂解，核碎片及凋亡小体形成。

RESULTS : Indomethacin induced apoptosis in wtp53 / SW480 cells .

荧光显微镜发现典型的核固缩及形态异常的有丝分裂中期细胞，DNA电泳发现典型的梯状DNA条带。

Nuclear condensation and abnormal metaphase cells were found by fluorescent microscopy . Typical DNA ladder was found by DNA electrophoresis .

IR组脑组织可见神经细胞核深染、固缩、细胞体积缩小。

Neuronal cells in brain tissue of IR group can be seen stained shrinkage , cell volume reduction . 3 .

IR组肝组织细胞表现为核固缩或破碎，嗜酸性增强，与周围细胞连接松散。

IR group , the liver cells showed nuclear condensation or fragmentation , eosinophils increased , loosely connected with the surrounding cells .

结果：在缺血6h组主要表现为：神经元固缩，有轻度水肿。

RESULTS : The major manifestations in 6 hours group were : shrank neurons , mild edema .

相差显微镜观察两者联合作用12h大量细胞固缩变圆，随时间延长胞体萎缩裂解。

Major cells shrunk in 12 h under phase-contrast microscopy , and cell body became atrophic and split with prolonged time .

结果射频烧灼后2h，角膜上皮细胞核染色质固缩、基质部分胶原纤维断离、内皮细胞线粒体肿胀、空泡；

Results The TEM showed corneal epithelial cells nuclear chromatin pyknosis , stromal partial colloid fibers rupture , endothelial cells mitochondria turgescence and vacuolization ;

28d组细胞固缩，难以找到线粒体；

In 28d model , there was pycnosis and few mitochondria could be found in ganglion cells .

结果EMP辐射引起以神经元变性和固缩为主的组织病理学改变，并导致神经细胞超微结构损伤。

Results Degeneration and consolidation of neurons were observed in hippocampal tissue after EMP radiation , ultrastructural injury could be seen as well .

HE染色和荧光染色后，在光学、荧光显微镜下可见Q3、HeLa细胞出现核固缩、碎裂、浓染及颗粒块状荧光等细胞凋亡的形态学变化。

After HE 、 fluorescence staining , optics and fluorescence microscope showed that AP extract could induce apoptosis of Q3 and HeLa Cells .

TUNEL染色所见阳性凋亡细胞，其凋亡特征为胞体缩小、核固缩、核碎裂、凋亡小体形成。

The apoptotic features of apoptotic positive cells found in TUNEL staining were shrinking cell body , nuclear pyrosis , nuclear fragmentation and the formation apoptotic body .

在粗线期中，X、Y染色体形成一定长度的SC，而未配对的染色体轴异固缩化，表现为多种不同的形态。

The axes of X and Y chromosome pair and form a SC of certain length at pachytene stage . The axes of unpaired X and Y chromosome are heteropycnotic and display various morphological complexities .

高倍镜下计数显示实验各组异常的细胞核明显多于对照组（P＜0.01），且随着酒精浓度增加，固缩核细胞数逐渐增加。

Counting under the high power microscope , we found that the number of abnormal nuclears increased in alcohol-treated group than control group ( P 0.01 ) . And that along with increasing of the alcohol concentration , the number of pycnosis cell were increasing gradually .

瘤体病理切片镜下观察：D组及E组肿瘤细胞密集排列，片状坏死区面积较小，细胞大小不一，形态各异，核大深染，可见核分裂象，核固缩较少。

Tumor biopsy were shows : Group D and Group E tumor cells are densely packed , has small necrosis area , cell shapes sizes , and a large deeply stained , visible mitotic activity , nuclear condensation is less .

CO组大鼠主动脉内皮细胞固缩，变性；表面有红细胞粘附，中膜中有大量的胶原纤维。

The endothelium of aorta shrunk and denatured , and there were some red blood cells adhered to the surface of endothelium in 13-14 months old sedentary rats . There were lots of collagenous fibers in the medium of endothelium .

另外，MI大鼠心肌组织切片观察到：心肌细胞基本结构紊乱，核固缩且染色加深，有的核甚至溶解消失。

In addition , we observed MI myocardial tissue sections and found that the basic structure of myocardial was disorder and nuclear become condensation and stained deepened and some nuclear melt away .

TH与Hoechst荧光染色显示，抑制剂组小鼠脑黑质部位有大量阳性细胞核固缩呈不规则形，核碎裂，部分裂解为多个凋亡小体。

TH and Hoechst staining showe that part of a large number of positive nuclei in SN were irregular shrinkage , nuclear fragmentation , some cracking to multiple apoptotic bodies .

用透射电镜观察了14只wistar大鼠在急性中度缺氧后的心肌超微结构变化，结果发现，急性缺氧后心肌超微结构改变明显，主要有线粒体固缩、水肿或空泡样变；

Transmission electron microscopy was used to observe the myocardial ultrastructure of 14 Wistar rats after acute moderate hypoxia . The results showed that changes in the myocardial ultrastructure were significant after acute hypoxia .

普鲁士蓝和腾氏蓝反应证实含铁化合物的沉积。皮层及杏仁体氯化亚铁注射部位、实验侧海马CA3区神经元减少，核固缩，胶质增生明显。

Deposition of iron-containing compounds into cortex and amygdaloid body were observed by Prussian blue and Turnbull blue stainings .

A、B、C组肿瘤细胞均有坏死，可见到细胞核完全溶解，细胞结构消失，均质、红染的细胞坏死表现，还可见到凋亡细胞，细胞质浓缩，细胞核深染固缩。

A , B , and C tumor cells are necrosis , shows the nucleus is completely dissolved , the cell structure disappears , homogeneous , red dye cell necrosis performance , you can still see apoptotic cells , cytoplasmic concentration , deeply stained nuclei , solid reduction .

惜助DAPI染色，可明显看到染色质固缩等典型的细胞凋亡特征。

The nuclei of transfected cells display the hallmarks of apoptosis by DAPI staining : chromatin condensation and clustering along the nuclei membrane .

动物一次口服吡喹酮120mg/kg后24h，皮层细胞质突起肿大，基质中分泌体减少，线粒体固缩；

24 hours after oral administration of single dose of 120mg / kg pyquiton to dogs infected with Pagumogonimus skrjabini , the tegumental cytoplasmic projections swelled , the mitochondria in the ground substance ;

结果如下：（1）在OA注射中心区神经元早期出现胞体固缩、肿胀、核移位，在注射3d时细胞破碎，发生坏死，并有大量炎性细胞浸润等病理现象；

The results showed that ( 1 ) the neurons in the center of the injection region displayed cytoplasmic shrinkage , swelling , nuclear pyknosis , and dislocation at the early stage , and necrosis appeared 3 d after the injection .

结果视网膜组织正常培养24h后，ISRN（RGCs和INL细胞）中可见少数细胞胞核固缩和坏死。

Results Some cells in ISRN ( include RGCs and INL cells ) showed pyknotic nuclei and necrosis after 24 h in control culture .

Ⅱ、Ⅲ组大鼠海马及皮层组织可见核深染、固缩，神经元丢失，并出现神经纤维缠结及淀粉样蛋白沉积等典型AD病理形态学变化，其中Ⅲ组大鼠变化更严重。

Rats of group ⅱ and ⅲ shows signs of hippocampal and cortex tissue visible hyperchromatic nuclei , solid shrinkage , loss of neurons , and the emergence of nerve fibers and tangles amyloid deposition pathological morphology typical AD change , especially for group ⅲ .

结果：铝过负荷致小鼠脑内MAO-B活力显著升高和CA1区出现明显神经元丢失及核固缩；

Results : Aluminum overload elevated MAO-B activity , caused karyopyknosis and loss of neurons in CA1 area of hippocampi , in dose-and time-dependent manners .

结果：DRG内感觉神经元的细胞体、细胞核及核仁均有不同程度固缩，用药后24~48h最为显著，5周后基本恢复。

Results : Oxaliplatin caused shrinkages of cytoplasm , nucleus , and nucleolus of the DRG sensory neurons with different extent . The effect peaked at 24-48 h and almost recovered after 5 weeks .

MAN，DXM，BC组脑组织水肿程度较BE组减轻，仅见少量的血管周围间隙增宽，偶有神经细胞核固缩，DXM组无神经细胞空泡样变性。

Light microscope inspection in MAN , DXM and BC groups showed lessened brain edema , slight increase of perivascular space , and occasional nerve cell pyknotic nucleus . We found on nerve cell vacuolar degeneration in DXM group .