内生肌酐清除率

糖尿病大鼠2周时，血糖、内生肌酐清除率、24h尿白蛋白量、肾重/体重均明显高于正常对照组（P<0.01）。

Blood glucose , Ccr , UAE , kidney / body weight were significantly elevated in the two week diabetic rats group than control group ( P < 0.01 ) .

结论与血清肌酐和内生肌酐清除率相比，血清CystatinC是一个更为准确、可靠的反映肾小球滤过功能的指标，对早期诊断各种慢性肾脏病患者肾小球滤过功能的损害具有重要价值。

Conclusion : Serum cystatin C determination is an accurate and reliable parameter of GFR . It can be a better endogenous marker for detection of early renal disfunction in patients with chronic kidney disease than serum creatinine and Ccr .

目的探讨血清胱抑素C、血清肌酐和内生肌酐清除率在糖尿病肾病早期诊断中的效能。

To research the effects of serum cystatin C , serum creatinine and CCr in the early diagnosis of diabetic nephropathy .

提高血白蛋白、红细胞、内生肌酐清除率以及钙水平均明显优于B组，二者比较有显著性差异（p＜0.01或P＜0.05）。

Increase albumen , red blood cell , creatinine clear rate and blood calcium ( p < 0.01 or p < 0.05 ) .

血尿素氮、血肌酐含量B组、D组、C组、A组依次降低，内生肌酐清除率则相反；

Blood urea nitrogen and blood creatinine content decreased in turns in Group B , Group D , Group C and Group A , but the endogenous creatinine clearance rate was adverse .

内生肌酐清除率（Ccr）<80ml/min为肾功能不全。

Renal insufficiency was defined as creatinine clearance rate ( Ccr ) less than 80 ml / min.

HC组的内生肌酐清除率显著低于H组，HC组的血清肌酐、钠钾排泄分数显著高于其它三组。

The values of serum creatinine , fractional excretion of sodium and potassium in group HC were significantly higher than those in the other groups .

影响vWF治疗前后变化幅度的主要因素为低密度脂蛋白、内生肌酐清除率的变化幅度；

The effect factors on vWF range of change were Alow density lipoprotein and A endogenous creatinine clearance rate .

根据患者血清肌酐水平计算内生肌酐清除率（Ccr）和造影剂肾病发生率。

Calculate the creatinine clearance rate ( Ccr ) and the incidence of CIN according to serum creatinine level .

此外，大鼠PTC密度与TI、内生肌酐清除率以及III型胶原、FN在小管间质表达密切相关（P<0.01）。

It was showed that PTC density was correlated with endogenous creatinine clearance , tubulointerstitial injury , collagen III and Fibronectin ( P < 0.01 ) .

结论CystatinC是肾小球滤过率监测中的一个较敏感的指标。联合应用CystatinC和24h尿内生肌酐清除率可以更准确地评估肾功能。

Conclusion Cystatin C is a sensitive index in monitoring glomerular filtration , which may be more accurate in evaluating renal function in combination with 24 h urine creatinine clearance .

测定治疗前后患者24小时尿微白蛋白排泄率（UAE）及内生肌酐清除率（CCr）。

Before and after therapy the rates of urinary microalbumin excretion ( UAE ) of 24 hours and creatinine clearance were detected .

光镜观察肾组织学改变。结果HC组和H组血清总胆固醇及肾血管阻力指数显著性增加，而内生肌酐清除率、肾皮质一氧化氮含量显著性降低。

Results Total serum cholesterol and resistance indices of renal blood vessels increased significantly , while creatinine clearance rate and production of nitric oxide in the renal cortex decreased markedly in group HC and group H .

治疗前后对比发现治疗后患者血压降低、内生肌酐清除率升高和血肌酐下降（P＜0.05或0.01），提示氨氯地平对肾移植后高血压患者有降压作用，并有保护移植肾的功能。

The blood pressure and blood creatinine decreased ( P < 0.01,0.05 ), while the endogenous creatinine clearance obviously increased ( P < 0.05 ) . The results pointed out that amlodipine has the effects of lowering blood pressure , protecting the transplanted kidney and improving the kidney function .

两组血液指标：4.1肾功能：治疗前，两组血尿素氮、血肌酐、血总二氧化碳结合率、血尿酸、内生肌酐清除率比较差异均无统计学意义（P＞0.05）。

The two groups of blood indicators : 4.1 Renal function : pre-treatment , two groups of blood urea nitrogen , serum creatinine , serum total carbon dioxide binding rate , serum uric acid , creatinine clearance rate ( Ccr ) had no statistically significant difference ( P 0.05 ) .

结果2组治疗后血浆白蛋白及24h尿蛋白定量均显著改善，而血肌酐、内生肌酐清除率均无明显变化。

Results After treatment , blood plasma albumin and 24 hours urine protein quantity were both improved significantly in the two groups , while there was no obvious change of serum creatinine and endogenous creatinine clearance rates .

方法39例肝硬化患者作为研究对象，应用放射性核素肾图评价肾功能状态，同步测定血浆中ATⅡ、内生肌酐清除率（Ccr）、血钠以及24h尿钠排泄水平。

Methods Thirty-nine cirrhotic patients were selected for evaluations of their renal function by radionuclide renogram , plasma AT ⅱ, endogenous creatinine clearance rate ( Ccr ), serum sodium and 24 h urinary sodium excretion .

两组治疗后内生肌酐清除率（Ccr）均较治疗前有所升高，组间、组内比较差异均无统计学意义（P0.05）。

After treatment , the endogenous creatinine clearance rate ( Ccr ) has both a little increased in the two groups before treatment , comparison within each group , and comparison between the two group shows no significant difference ( P0.05 ) .

于造影前及造影后第1、6天分别监测血肌酐（Scr）、内生肌酐清除率（Ccr）、血渗透压、尿渗透压、24h尿蛋白定量、尿常规。

Before and 1 , 6 days after operation , serum creatinine ( Scr ), endogenous creatinine clearance rate ( Ccr ), osmotic pressur in blood and urine , 24 h urine protein were monitored and urine routine test was done .

结果与对照组比较，CsA组24h尿量、小管间质损伤评分、OPN表达和ED-1阳性细胞计数均增加，内生肌酐清除率（Ccr）下降（P均<0.05）。

Results Compared to control group , the 24-hour urine of rats , histological scores , the expression of OPN and the ED-1 positive cells number of CsA group were significantly increased , but Ccr was significantly lower ( P < 0.05 ) .

方法30例慢性肾炎患者，内生肌酐清除率（Ccr）0.5ml·s-1/1.73m2，中度高血压。

Methods Thirty cases of chronic glomerulonephritis in which endogenous creatinine clearance rate was 0.5ml · s - 1 / 1.73m 2 , with sitting diastolic blood pressure ≥ 95 and ≤ 114mmHg were randomized .

结果：两组疗效、症状消失时间（除血尿外）、血浆比黏度、24h尿蛋白定量、内生肌酐清除率（Ccr）和血肌酐（Scr）差异均有显著性（P<0.05～P<0.01）。

Results : There was significant difference between the two groups in the time of symptom disappearing , the plasma contrast viscosity , 24 h urine protein quantization and creatinine clearance rate ( Ccr ) and serum creatinine ( Scr )( P < 0.05 to P < 0.01 ) .

目的通过检测降钙素基因相关肽（CGRP）在糖尿病肾病不同阶段的含量及其与内生肌酐清除率（Ccr）之间的相关关系，探讨CGRP在糖尿病肾病发展过程中的变化及其作用。

Objective To study the role of calcitonin gene-related peptide ( CGRP ), and the relationship between CGRP and endogenous creatinine clearance rate ( Ccr ) in the development of diabetic nephropathy , the plasma levels of CGRP and Ccr were measured in different stages of patients with diabetic nephropathy .

方法检测了正常人、慢性肾小球肾炎患者血浆内皮素（PET-1）和24小时尿内皮素排泄量（UET-1），内生肌酐清除率（Ccr）和尿β2微球蛋白（β2-m）。

Methods Plasma endothelin-1 ( PET-1 ) N urinary excretion rate of endothelin-1 ( UET-1 ) . , creatinine clearance ( Ccr ) and urinary excretion rate of 2-microglobulin (β 2-m ) in 27 patients with chronic glomerulonephritis and in 10 normal control were measured .

瘦体重法推算内生肌酐清除率的临床应用

The clinical application of creatinine clearance predicted from lean body weight

处死前测定血肌酐、尿肌酐，计算内生肌酐清除率；

Before sacrificed , creatinine clearance ( Ccr ) was measured .

流行性出血热内生肌酐清除率的动态变化

Change Clinical Study of Endogenous Creatinine Clearance Rate in EHF

老年人海滨疗养前后内生肌酐清除率的变化

The changes of endogenous creatinine clearance of aged people before and after seaside convalescence

血清肌酸酐，内生肌酐清除率，蛋白尿，血压在基线水平。

Serum creatinine , creatinine clearance , proteinuria and blood pressure were recorded at baseline .

同时测量血、尿肌酐，计算内生肌酐清除率。

The concentrations of serum and urine creatinine , and the creatinine clearance were also measured .