黑素

研究了泰和乌骨鸡及其黑素对果蝇寿命及小鼠SOD活性的影响。

The effects of Chinese Taihe chicken and its melanin on age of fruit fly and activity of SOD ( superoxide dismutase ) in mouse were studied .

结果：EGCG显著抑制黑素合成和TYR活性，且呈浓度依赖性；

Results : The results showed that EGCG inhibited melanin synthesis and tyrosinase activity significantly compared with control .

壬二酸对人黑素细胞和鼠黑素瘤B（16）细胞黑素合成功能的影响

Effects of Azelaic acid on melanin synthesis of human melanocyte and mouse B16 melanoma cells in vitro

黑素皮质素受体是G蛋白耦联受体超家族成员。

The melanocortin receptors are members of the super-family of G-protein coupled receptors .

结果：更年期大鼠下丘脑阿片促黑素皮质素原mRNA表达明显降低；

Result : The expression of POMC mRNA was down regulated in hypothalamus of the female climacteric rats .

双氯灭痛对豚鼠表皮角质形成细胞/黑素细胞比值及前列腺素E2含量影响的实验观察

Effect of diclofenac sodium on KC / MC ratios and content of PGE_2 in epidermis of the full-thickness skin autografts

8调节酪氨酸酶相关蛋白家族成员的活性，黑素小体中pH值大小以及SH基团的数目。

Control of activity of tyrosinase-related proteins .

正常人MC胞内的黑素小体为弱酸性，pH值在5.5-6.8之间，酪氨酸酶的最适pH值为6.8。

Melanosomes were acidic with pH 5.5-6.8 in normal human melanocyte and the optimal pH for tyrosinase was 6.8 .

结论：H2O2有抑制正常人表皮黑素细胞增殖的作用。

Conclusion : H_2O_2 could inhibit the proliferation of human epidermal melanocytes .

原阿片碱醋酸盐的结构探讨调神益肾针法对更年期大鼠下丘脑阿片促黑素皮质素原mRNA表达的影响

Effect of acupuncture therapy of regulating mentality and supplementing kidney on the expression of proopiomelanocortin mRNA in hypothalamus of climacteric rats

点阵CO2激光治疗紫外线照射所致豚鼠皮肤色素沉着后豚鼠表皮黑素沉着程度降低。

The extent of skin pigmentation in guinea pig induced by UVB bring down after fractional CO2 laser treatment .

白癜风患者血清自身抗体IgG识别人黑素浓集素受体-1B细胞表位的研究

B Cell Epitopes of Human Melanin-Concentrating Hormone Receptor 1 Recognized by Serum Autoantibodies from Patients with Vitiligo

因AKautoAb是正常人血清中提取的物质，用其培养的黑素细胞在临床移植应用中将更具安全性。

The safety of transplantation of the melanocytes grown with AK auto Ab was discussed .

以酶联免疫吸附法检测283例白癜风患者血清中的抗黑素细胞IgG抗体；

Anti pigment cell IgG antibodies in the sera of 283 patients with vitiligo was detected by ELISA ;

寻常型银屑病皮损中，Bcl-2蛋白基本不表达，与正常皮肤组织中的表达相似（P＞0.05），局限于基底层黑素细胞，角质形成细胞未见阳性表达。

And the expression of Bcl-2 protein was like normal epidermis ( P > 0.05 ) , restricted only in melanocytes of the basal layer .

白癜风患者血清中抗黑素细胞IgG、IgM抗体的检测及补体介导的血清细胞毒反应

Detection of autoantibodies to melanocytes in vitiligo patients ' sera and sera induced cytotoxicity mediated by complement

结果：用含TPA培养液容易获得纯化的黑素细胞；

RESULT : The purification melanocytes were easily obtained with TPA culture medium ;

bFGF对人毛囊黑素细胞增殖、活化和黑素合成作用的研究

Effect of bFGF on proliferation , activation and melanin synthesis of human hair follicle melanocytes in vitro

并对部分患者进行血清抗黑素细胞IgG抗体及白介素-6、白介素-8检测。

The serum levels of IgG antibodies to melanocyte , IL-6 , IL-8 were measured in some patients with vitiligo .

α-黑素细胞刺激素对两次打击ARDS模型大鼠的保护作用及其机制研究

Protective Effect and Mechanism of α - melanocyte Stimulating Hormone on the Two-hit ARDS Rat Model

体外培养人黑素细胞HLA-DR抗原的表达

THE HLA-DR antigen expression on human melanocytes in vitro and after growth in culture

了解白癜风黑素细胞的消失与角朊细胞产生的内皮素-1（ET-1）水平的关系。

Objective To study the expression of endothelin-1 ( ET-1 ) mRNA in keratinocytes in patients with vitiligo .

结果提示：1.CSN较AN易于恶变，2.异常黑素小体并非只限于MM。

These results suggest that : ( 1 ) CSN be easier to become malignant than AN ; ( 2 ) Abnormal melanosomes be not unique in MM .

UVA与UVB对人体黑素细胞生长的影响

Influence of UVA and UVB on Human Melanocytes Growth

结论用体外培养的人黑素细胞作为研究对象与鼠黑素瘤B16细胞比较具有一定的差异；

Conclusion There is a biological diversity between human melanocytes and murine melanoma cells .

目的：探讨过氧化氢（H2O2）对体外培养的黑素细胞形态和功能的影响。

Objective : To determine the effect of hydrogen peroxide ( H_2O_2 ) on configuration and function of cultured melanocytes .

黑素细胞皮质激素受体（MC4R）是跨膜G蛋白偶联受体。

Melanocortin receptor 4 ( MC4R ) is one of cross membrane G protein coupling acceptor .

酪氨酸酶相关蛋白1（tyrosinaserelatedprotein1，TRP-1）是黑素细胞和恶性黑素瘤细胞中含量最丰富的糖蛋白，其基因是第一个克隆成功的色素基因。

TRP-1 ( tyrosinase related protein 1 , TRP-1 ) or glycoprotein 75 is the most abundant glycoprotein in melanocytes .

肢端黑素瘤和黑素痣的AgNOR

AgNOR in Acral Melanoma and Melanotic Nevi

烟酰胺对人皮黑素细胞的作用及其对UVA辐射后的干预

Biological Effects of Nicotinamide on Human Skin Melanocytes and the Intervention after UVA Radiation