黄芩苷元

黄芩苷元选择性诱导人白血病K562细胞凋亡

Baicalein selectively induce apoptosis in human leukemia K562 cells

黄芩苷元对心肌缺血再灌注损伤大鼠心肌能量代谢及NO和细胞凋亡的影响

Effects of baicalein on energy metabolism , nitric oxide and apoptosis of myocardial ischemia-reperfusion injury in rats

黄芩苷元的Mannich反应

Mannich Reaction of Baicalein

结果黄芩苷元能选择性抑制人白血病K562细胞生长且呈浓度依赖关系，并能诱导细胞凋亡，细胞增殖被阻滞于S期；

Results Baicalein was shown to significantly inhibit the proliferation of K562 cell in a dose-dependent manner and selectively induce apoptosis of human leukemia K562 cells . Flow cytometric analysis showed that baicalein arrested K562 cells in the S phase .

7种黄酮类化合物亲和力的排列顺序为：白杨素>汉黄芩苷元>红花素>黄芩素>5,6,7三羟基4′甲氧基黄酮>异红花素>白杨素7葡萄糖醛酸苷。

Based on binding to BZD S , the order of the affinity among these compounds was chrysin > wogonin > carthamidin > scutellarein > 5,6,7 trihydroxy 4 ′ methoxyflavone > isocarthamidin > chrysin 7 O β D glucuronide .

纤维素酶辅助提取生黄芩饮片中黄酮苷元的工艺研究

Study on Cellulase-assisted Extraction of Flavonoid Aglycons from Skullcap Root