麦迪霉素

HPLC定量分析麦迪霉素

Quantitative analysis of Midecamycin by HPLC

结果1994～1998年氨基糖苷类、硫霉素、多粘菌素B、克拉霉素、麦迪霉素均无耐药菌；

RESULTS All of campylobacters were isolated from 1994 to 1998 . No strain was resistant to aminoglycosides , imipenem , polymycin B , clarithromycin , josamycin , midecamycin .

研究了茜素与麦迪霉素（MID）、红霉素（ERY）的显色反应。

The colour reactions of alizarin ( ALZ ) with midecamycin ( MID ) and erythromycin ( ERY ) were investiga-ted .

在pH5.5~6.8的BR缓冲溶液中，茜素与麦迪霉素（MID）、红霉素（ERY）反应生成红色络合物。

In the BR medium at pH 5.5 ~ 6.8 alizarin ( ALZ ) reacts with midecamycin ( MID ) or erythromycin ( ERY ) to form red compounds .

CAD-45大孔吸附树脂提取分离麦迪霉素的研究

Studies on Extraction and Isolation of Midecamycin by Macroreticular Resin Adsorbent CAD-45

CAD-40大孔吸附剂提取麦迪霉素试验研究

An experimental study on the adsorption of mydemycin using the cad-40 macroporous adsorbent

方法：对中国大耳白兔分别给予剂量为0.3g口服用麦迪霉素混悬剂、直肠用普通麦迪霉素栓剂及麦迪霉素微囊栓剂，管碟法测定麦迪霉素含量。

Methods : The drug concentrations were determined by cylinder plat after a single oral dose of 0.3g preparation of suspension , suppository and micro capsule embolus in Chinese rabbits respectively .

以试管稀释法、测定分离菌株对5种敏感药物的平均MIC分别是：利福平0.24、环丙沙星0.70、氧氟沙星0.70、氟啶酸1.20和麦迪霉素7.80μg/ml。

By the method of test tube dilution , the drug resistance of 60 isolated strains were tested with the 5 susceptible agents above . The average MIC of them were rifampicin 0.24 , ofloxacin 0 . 70 , cipro-floxacin 0.70 , enoxacin 1.20 and midecamycin 7.80 μ g / ml.

麦迪霉素的油/水界面循环伏安法研究及其测定

Cyclic voltammetry and determination of medemycin at water / oil interfaces

麦迪霉素产生菌酮基还原酶基因在大肠杆菌中的表达

Expression of the polyketide ketoreductase gene from Midecamycin producing strain in E.coli

三种剂型麦迪霉素兔体内的血药浓度测定

Determination of Drug Concentrations of Three Midecamycin Preparations in Rabbits

麦迪霉素肠溶制剂溶出度测定苯妥英钠缓释片溶出度的研究

Dissolution rate study on phenytoin sodium sustained release tablets

注射用麦迪霉素治疗急性感染性疾病292例的临床总结

The treatment of 292 cases acute pyogenic infections by intravenous administration of medemycin

两株麦迪霉素产生菌的稳定性试验

Experiment on the stability of two Midecamycin producing strains

非晶形醋酸麦迪霉素的制备及其理化性质

Preparation and its physico-chemical properties of amorphous Midecamycin acetate

大环内酯类抗生素麦迪霉素的电化学特性

The electrochemical behavior of a large ring lactone

用薄层层析法来定性分析醋酸麦迪霉素合成过程的酰化中间体。

The qualitative analysis of the intermediates in synthesis of midecamycin acetate is described .

麦迪霉素肠溶胶囊剂生物利用度的测定

A Measurement on Bioavailability of Midecamycin Capsules

目的：建立浊度法测定麦迪霉素片剂含量的方法。

Objective : To establish a turbidimetric method for determination the content of Midecamycin tablets .

麦迪霉素栓家兔直肠给药吸收的研究

Rectal absorption of Medecamycin suppositories in rabbits

快速测定麦迪霉素效价的微生物比色法

A rapid colorimetric bioassay of Medecamycin

麦白霉素与麦迪霉素及其组分的体内外生物活性分析与比较

Assay and comparison of in vitro and vivo activities of meleumycin , medemycin and their components

国产麦迪霉素静脉滴注治疗急性化脓性感染120例初步临床观察

Clinical evaluation of home-made intravenous Medecamycin preparation in the treatment of 120 cases of acute suppurative infections

麦迪霉素微囊栓剂在较短的时间（1小时）达到最高血药浓度（2.58μg/ml），且可维持血药浓度大于最低抑菌浓度8～9小时。

However , the micro capsule embolus reached the highest concentration ( 2.58 μ g / ml ) with a shorter time ( 1 h ) and maintain concentration over minimum inhibitory concentration for 8 ~ 9 h.

方法：以麦迪（白）霉素专用培养基中加入适量葡萄糖进行效价测定。

Method : Acetylspiramycin titer was determined by suitable glucose were added into the special culture medium of midecamycin .