胍乙啶

注射胍乙啶后大鼠血压与组织儿茶酚胺的关系

Relationship between blood pressure and tissue catecholamines in rats injected with guanethidine

胍乙啶的作用是蓄积性的，且可维持较长时间。

The effects of guanethidine are cumulative over extended periods .

腹腔注射胍乙啶20毫克/公斤后5小时，NA已近耗尽；

Intraperitoneal injection of guanethidine sulphate 20 mg / kg caused a well-nigh complete depletion in 5 hours .

给苯乙肼3天后再注射胍乙啶20&100毫克/公斤，心脏NA未见减少。

If guanethidine sulphate 20 & 100 mg / kg was given subsequent to a 3-day administration of phenelzine , the NA did not decrease .

根据以上结果，苯乙肼似能加强酪胺释放心脏NA的作用，能部分减少利血平对心脏，NA的耗尽作用，但可完全对抗胍乙啶的释放作用。

The above results may be summarized by saying that the NA-releasing action of tyramine seemed to be augmented , that of reserpine was partly diminished and that of guanethidine was wholly antagonized by phenelzine .

胍乙啶、胍乙哌啶、BD-37和BD-31抑制酪胺的升压作用；

P , BD-37 , BD-31 and G inhibited the hypertensive effect of tyramine .

对去甲肾上腺素的升压，除BD-31稍有抑制外，胍乙啶、BD-37和BD-38反有增敏作用。

BD-37 , BD-38 and G sensitized , but BD-31 inhibited slightly , the hypertensive effect of noradrenaline .

胍乙啶、胍乙哌啶、BD-37和BD-38可减低大鼠心脏内去甲肾上腺素的含量，BD-31未见减低。

P , BD-37 , BD-38 and G decreased , but BD-31 did not decrease , the noradrenaline contents in the rat heart .

胍乙啶、胍乙哌啶和BD-37明显增强豚鼠心房的收缩，BD-38和BD-31则无此作用。

P , BD-37 and G markedly augmented the contraction of guinea pig auricles , though BD-31 and BD-38 were devoid of this action .

清醒猫静脉注射胍乙啶和BD-38（5或10mg/kg）引起瞬膜松弛的作用强度相同。

In conscious cats , iv guanethidine sulphate or BD-38 ( 5 or 10 mg / kg ) brought about relaxations of nictitating membranes of similar intensity .

麻醉大白鼠和猫静脉注射胍乙啶、胍乙哌啶和BD-37出现血压短暂下降继而升压，然后再下降，而BD-38和BD-31仅有降压作用。

Intravenous injections of P , BD-37 and G in anaesthetized rats and cats brought about a transient lowering of blood pressure , followed by a rise and then a gradual decline , whereas BD-31 and BD-38 produced only a hypotension .

胍乙啶对大白鼠肾上腺皮质活动的影响

Effect of guanethidine on adrenal cortical activities in rats

胍乙啶和利血平对猫肾上腺素释放及肾机能的作用

Effects of guanethidine and reserpine on epinephrine liberation and renal function in cats

交流示波极谱滴定法测定硫酸胍乙啶的含量

Determination of Guanethidine by Ac Oscillopolarographic Titration Method

胍乙啶对单纯和联合培养的心肌细胞自发搏动频率的影响

The influence of guanethidine sulfate on spontaneous contraction frequency of cardiac muscle cells with and without adrenergic innervation

正常大白鼠注射胍乙啶后，各器官及组织内合血量普遍有增加趋势，其中以脾及肾的血容量增加最为明显，说明胍乙啶对这些部位的血管有扩张作用。

Normal rats receiving guanethidine revealed an increase of blood volumes in all organs , especially spleen and kidney .