顶体

蛋白激酶C对精子活力和顶体反应的影响

Influence of Protein Kinase C on Motility and Acrosome Reaction of Sperm

结果表明：1.γ－氨基丁酸可明显地诱发人精子顶体反应（P＜0.05）。

The results showed : 1.GABA can induce human sperm acrosome reaction ( P0.05 );

蛋白C抑制剂对人精子顶体反应和顶体素活性的影响

The Effect of Protein C Inhibitor on Human Sperm Acrosome Reaction and Acrosin Activity

从顶体反应率来看，鲜精的获能效果明显优于冻精，二者差异极显著（P＜0.01）。

Acrosome reaction rate indicated fresh sperm was significantly higher than freeze-thawing sperm ( P < 0.01 ) .

较低渗透压使精子顶体完整率下降轻快（P＜0.01）。

The intact rate of acrosome decreased markedly ( P < 01 ) under the lower osmotic pressure .

MR定位于：1.AR早期的精子顶体区质膜表面；

MR localized on : 1.the surface of PM of sperm at the earlier stage of AR ;

头部顶体明显突出，呈倒V形；

The acrosome is V shaped in upside down .

精子顶体素ELISA检测法的建立与临床应用

Establishment and clinical application of examining acrosin in sperm with ELISA

节律基因Clock对雄性小鼠顶体酶活性的影响

Influence of circadian gene , Clock , on the acrosin activity in male mice

PLC在调控信号转导通路中的特性使其在顶体反应、卵子激活中发挥了巨大的作用。

PLC plays important roles not only in sperm acrosome reaction but also in egg activation .

顶体完整率分别为34.47±5.20和29.77±4.37（P＜0.01）。

, and the percentage of sperms with intact acrosome were 34.47 ± 5.20 and 29.77 ± 4.37 ( P < 0.01 ) resp .

变态期精子Ca￣（2＋）则分布于精子顶体内膜与核膜之间。

On elongate spermidCa ￣( 2 + ) only located in space between inner acrosomal membrane and nuclear membrane .

在精子畸形率、顶体异常率方面，实验组低于对照组，差异显著（P＜0.05）；

The deformity rate of sperm and abnormal rate of acrosome in test group were lower than control group and the difference was marked ( p < 0.05 ) .

精细胞中期，MTmRNA主要在原顶体囊，一些信号在膜复合体中。

At the middle spermatids , MT mRNA predominates in the proacrosomal vesicle , some in the membrane complex .

目的探讨白色念珠菌性阴道炎对人精子顶体反应（AR）的影响机制。

Objective : To explore the mechanism of C.albicans vaginitis on acrosome reaction ( AR ) in human sperm .

300IU/mlSOD对精子的顶体和活力有显著提高，能够有效延长精子的存活时间（P0.05）。

300IU / ml SOD could improve the sperm motility , livability and the acrosomal and membrane integrity rates ( P0.05 ) .

目的研究人精子的甘露糖受体（MR）表达与顶体反应的关系，以探讨体外获能培养精子的MR表达是否为人精子获能的标志。

Objective To study the correlation between expression of mannose-ligand receptor ( MR ) on capacitated human sperm in vitro and acrosome reaction induced by zona pellucida ( ZP ) .

精浆抗精子抗体阳性不育患者顶体酶及SOD活性的变化

The change of semen superoxide dismutase ( SOD ) and acrosin activity in the sterility of male patients with positive antisperm antibody

AR期间精子的顶体小泡表面、顶体内膜及顶体基质；

The surface of membrane vesicles , inner acrosomal membrane ( IAM ) or rarely acrosomal matrix of acrosome reacting spermatozoa ;

在顶体期的精子细胞核内钙沉淀主要分布于核膜上，核质中偶见Ca2＋沉淀。

The Ca2 + deposits of the spermatids in the acrosomal phase distributed mainly on the nuclear membrane .

TEST组与EYC组的顶体完整率差异显著（P0.05）。

There was significant difference ( P0.05 ) between TRIS and EYC at acrosomal and membrane integrity .

结果发现，作为电子致密体的CA前体和原顶体颗粒出现在副核和细胞核之间区域。

It is found that the CA is an electron dense body and the proacrosomal granule appear in the region between the nucleus and the nebenkern .

原位杂交实验表明早期精细胞中，MTmRNA主要集中在原顶体囊，一些信号在细胞质中。

In situ hybridization result showed that at the early spermatids , abundant MT mRNA concentrates into proacrosomal vesicle , some in cytoplasm .

目的：探讨一氧化氮（NO）对人精子获能及顶体反应（AR）的影响。

Objective : To explore the effect of nitric oxide ( NO ) on human sperm capacitation and acrosome reaction ( AR ) .

PAF对长白猪精子活率及顶体反应率的影响

The influence of PAF on sperm living rate and AR of a long white pig

精细胞后期和成熟精子中，MTmRNA集中在顶体管以及顶体和杯状核之间的狭带中。

At the late spermatids and spermatozoa , MT mRNA localizes in the acrosomal tubule and the narrow band between cup-like nucleus and acrosome .

在精子顶体反应前后，Fβ在精子表面均特异性定位于精子头部赤道区域和顶体内膜区域。

The fertilin beta subunit was immunized localized to both the equatorial region and inner acrosomal membrane region of the sperm membrane during before and after acrosomal reaction .

免疫组织化学显示膜联蛋白A1主要分布于精原细胞核、精子细胞顶体帽及精子胞质残余体内。

Annexin A1 mainly distributed in nuclei of spermatogonia , acrosomal cap of spermatid and residual body of sperm .

结论：总体上，Cd诱导公牛精子膜损伤、活动率降低、DNA断裂、以及顶体反应率降低而导致精子功能损伤。

Conlusion : Collectively , Cd induced membrane impairments , lowered motility , DNA breaks and a decreased rate in the acrosome reaction of bull spermatozoa , leading to sperm dysfunction .

精子形态学检查中，顶体形态不规则的比例在正常受精和受精障碍的比较中有明显统计学意义（P0.05）6.透射电镜对光镜下不同畸形精子的结构和功能分析。

There was significant statistical difference ( P0.05 ) in the rate of irregular acrosome between normal and disord fertilization by the test of sperm morphology . 6 .