青蒿琥酯

结果：药物浓度和pH值对青蒿琥酯的经皮渗透产生主要影响。

Result : Drug concentration and pH were the main factors which affected the percutaneous penetration of artesunate .

EVA膜对青蒿琥酯经皮渗透影响的研究

A study on the Transdermal Penetration of Artesunate from various EVA Membranes

Bcl-2反义核酸增强青蒿琥酯诱导K562细胞凋亡

Bcl-2 antisense oligodeoxynucleotides to enhance the apoptosis-inducing effect of artesunate on K562 cells

青蒿琥酯诱导人白血病细胞K562凋亡的实验研究

The apoptosis-inducing effect of artesunate on human leukemia K562 cells

青蒿琥酯为青蒿提取物青蒿素的衍生物，它不仅保留了青蒿的功效，且现代研究显示其具有免疫抑制和免疫调节作用，故可以用来治疗SLE。

Artesunate has a immune double adjusting effect and can treat SLE .

青蒿琥酯对K562细胞凋亡诱导作用及其与亚砷酸的协同作用

Apoptosis-inducing effect of artesunate on K562 cells and its synergy with arsenious acid

SOD检测在中枢神经系统白血病诊断中的意义及青蒿琥酯干扰作用机制探讨

Study on the Value of SOD Activity Test in Diagnosis of CNSL and the Mechanism Involved in Artesunate Interference

青蒿琥酯对HeLa细胞生长的抑制作用

Inhibiting effect of artemisinin on HeLa cell growth

中药青蒿琥酯联合应用TRAIL有望成为临床治疗前列腺癌新的治疗方案。

Chinese medicine Artesunate combinate with TRAIL will be a new therapeutic regimen in clinic therapy of prostate carcinoma .

目的观察青蒿琥酯对人白血病细胞株K562抑制增殖和凋亡作用。

Objective To investigate the proliferation inhibition and apoptosis-inducing effect of Artesunate on human leukemia K562 cells .

结果：对照组和青蒿琥酯组移植皮肤平均存活时间分别为12.1±2.088d和16.8±3.633d（P＜0.01）。

Results : The mean survival time of skin grafts in the control group and experimental group was 12.1 ± 2.088 and 16.8 ± 3.633 days , respectively ( P < 0.01 ) .

青蒿琥酯对内毒素信号转导通路中CD14的影响

Effects of artesunate on CD14 in LPS signal transduction pathway

研究目的：通过对青蒿琥酯诱导急性白血病（AL）病人原代细胞凋亡的实验及临床研究，为青蒿琥酯治疗急性白血病提供实验及临床方面的依据。

[ Objective ] To observe the apoptosis-induction function of Artesunate on the primary cells of patients with Acute Leukemia ( AL ) through experiment and clinical research ;

青蒿琥酯对人胃癌SGC-7901细胞生长的影响

The Effects of Artesunate on Gastric Cancer SGC-7901 Cells

青蒿琥酯对H22荷瘤小鼠肿瘤组织FasL的影响

Effect of artesunate on tumor FasL expression in mice of transplanted hepatocarcinoma 22

目的：观察青蒿琥酯对佐剂性关节炎大鼠踝关节滑膜的病理形态和滑膜细胞的NF-κB、bcl-2表达的影响。

OBJECTIVE To observe the effect on the expression of NF - κ B and bcl-2 in synovium of joint of sodium artesunate in treating adjuvant arthritis of rats .

青蒿琥酯钠对体外大鼠红细胞膜钠-钾交换ATP酶的抑制

Inhibition of sodium artesunate on rat erythrocyte membrane Na ( + ) - K ( + ) - exchanging ATPase in vitro

青蒿琥酯（Artesunate）具有免疫双向调节作用已为现代实验所证实。

Artesunate has an immune double adjusting effect .

通过比色法检测青蒿琥酯作用前后K562／DOX细胞谷胱甘肽-S-转移酶活性的变化。

The activity of glutathione S-transferases ( GSTs ) of K562 / DOX cells detected by chromometry .

青蒿琥酯及蒿甲醚治疗G6PD缺乏的间日疟疗效观察

Observation on the effect of artesunate and artemether on patients with G6PD dificiency vivax malaria patients

青蒿琥酯钠对乳腺癌细胞株MCF-7、MDA-MB-231增殖和凋亡影响的实验研究

The Effects of Artesunate on the Proliferation and Apoptosis of Breast Cancer Cell Lines MCF-7 and MDA-MB-231

目的：观察青蒿琥酯对人宫颈癌HeLa细胞的乏氧杀伤及辐射增敏作用的影响。

Objectives : To investigate the effect of hypoxic killing and radiation sensitivity of artemisinin on human cervical carcinoma cell line HeLa cell .

目的探讨中暑内毒素血症时，青蒿琥酯对内毒素信号通路中CD14表达的影响。

Objective To discuss the effects of artesunate on CD14 expression in LPS signal transduction pathway while heatstroke endotoxemia .

这种药现有的两种抗疟药青蒿琥酯（artesunate）和氨酚喹（mefloquine）的二合一药。

The medicine combines two existing malaria drugs , artesunate and mefloquine .

体内外实验研究青蒿琥酯联合热疗对A549细胞生物学特性影响

Study on the effect of artesunate combined thermotherapy in vivo and in vitro on the bionomics of human lung adenocarcinoma A549 cell line

结果青蒿琥酯抑制K562细胞的增殖，IC50值为12.41μg/mL，其有时间、剂量-效应关系；

RESULTS : The cell proliferation was inhibited by artesunate and IC_ 50 at 48 h was 12.41 μ g / mL.

目的对比观察青蒿琥酯（Art）和阿苯达唑（Alb）治疗继发性棘球蚴病后，小鼠的免疫转归及肝功能变化。

Objective To observe the influence of Artesunate ( Art )( a Chinese herb medicine ) on immune function and on hepatic function of mice after Art against the secondary murine echinococcosis .

目的研究青蒿琥酯治疗狼疮样小鼠后肾脏白细胞介素6（IL-6）和转化生长因子β（TGF-β）表达的改变及其临床意义。

Objective To study the effect of artesunate on renal expression of interleukin-6 ( IL-6 ) and transforming growth factor - β( TGF - β) in SLE-like mice and its clinical significance .

结论：青蒿琥酯在体外一定浓度范围内可诱导K562细胞株凋亡，bcl2反义核酸可增强青蒿琥酯诱导K562细胞凋亡的作用。

CONCLUSION : Artesunate could induce the apoptosis of K562 cells within a certain dose range in vitro , and bcl-2 ASON could enhance the apoptosis-inducing effect of artesunate .

目的：研究青蒿琥酯钠（SA）对大鼠的抗孕作用以及其对妊娠及假孕大鼠血清孕酮含量和蜕膜组织的影响，以探讨其终止妊娠的机理。

OBJECTIVE : To study the effect of sodium artesunate ( SA ) on content of progesterone and decidua of pregnant rats and investigate the efficacy and mechanism of SA for termination of early pregnancy .