雄酮

25℃以雄酮为底物，以NAD+和thioNAD+为辅因子时，融合蛋白参与酶促反应的最适pH分别为105和94。

With androsterone as the substrate and NAD + and thio NAD + as the cofactor , the optimum pH for the enzymatic reaction at 25 ℃ was 10 5 and 9 4 respectively .

肾上腺皮质的主要产物为醛固酮、皮质醇和脱氢异雄酮硫酸盐。

The principal adrenocortical products are aldosterone , cortisol and dehydroepiandrosterone sulphate .

结果绝经期妇女接受三苯氧胺治疗3个月后血清雌二醇、雌酮、脱氢表雄酮浓度均有不同程度的升高，以雌二醇的升高有显著性（P＜0.01）；

Results The serum estrogen levels in postmenopausal women significantly increased after three months'therapy .

简单节杆菌生物转化17α-甲基睾丸素C（1，2）-脱氢制备美雄酮

Bioconversion of 17 α - mehyl-testosterone for Preparation of Methandienone with Arthrobacter Simplex

HPLC法测定去氢表雄酮片的含量

Determination of the Content of Dehydroepiandrosterone in Dehydroepiandrosterone Tablets by HPLC

脱氢表雄酮对SLE患者外周血淋巴细胞体外凋亡的影响

The influence of dehydroepiandrosterone on in vitro apoptosis of peripheral blood lymphocytes in patients with SLE

LC-MS法测定人血浆中脱氢表雄酮硫酸酯的浓度

Spevack process Determination of Dehydroisoandrosterone Sulfate in Human Plasma by LC-MS

脱氢表雄酮对内皮细胞NO，ET-1生成及ICAM-1表达的影响

Influence of dehydroepiandrosterone on production of NO , ET-1 and expression of ICAM-1 in endothelial cells

脱氢表雄酮对氧化低密度脂蛋白诱导的人脐静脉内皮细胞表达VCAM-1的影响

Effects of Dehydroepiandrosterone on Ox-LDL-induced VCAM-1 Expression in Human Umbilical Venous Endothelial Cells

结论：脱氢表雄酮（DHEA）可以诱导较为理想的多囊卵巢综合征动物模型。

Conclusion : DHEA can induce the ideal PCOS animal model .

目的：研究脱氢表雄酮（DHEA）对大鼠实验性骨关节炎（OA）的影响。

AIM : To investigate the effects of dehydroepiandrosterone ( DHEA ) on experimental osteoarthritis in rats .

脱氢表雄酮对兔骨关节炎软骨和滑膜中MMP-3、TIMP-1和IL-1βmRNA表达的影响

Effect of dehydroepiandrosterone on mRNA expression of MMP-3 , TIMP-1 and IL-1 β in the cartilage and synovium of rabbits with osteoarthritis

脱氢表雄酮与哮喘模型大鼠血清内IFN-γ、IL-4、IGE水平的探讨

Dehydroepiandrosterone ( DHEA ) Affect the Level of IFN - γ、 IL-4 、 IgE in Serum of the Asthmatic SD Rat Models

目的探讨小剂量（≤50mg）脱氢表雄酮硫酸酯（DS）对老年男性记忆力的影响。

Objective To study the effect of small dosage dehydroepiandrosterone sulphate ( DS )(≤ 50 mg ) on memory of aged males .

2）下丘脑垂体肾上腺轴：脱羟表雄酮（DHEA）和其硫酸盐（DHEA-S）逐步减少。

Hypothalamus - Hypophysis-Adrenal axis , the DHEA and DHEA-Sulfate secrete less .

肥胖组血清硫酸脱氢表雄酮（DHEAS）水平显著高于对照组；

Serum dehydroepiandrosterone sulphate ( DHEA-s ) level in obesity group was higher than that in control group .

目的探讨脱氢表雄酮（DHEA）对成骨细胞（osteoblasts，OB）及CD4+T细胞表达协同刺激分子的调控作用。

Objective To investigate modulation of DHEA in the costimulatory molecule of the osteoblasts ( OB ) and CD4 ~ + T lymphocytes .

结果BMS组睾酮、雄烯二酮、硫酸脱氢表雄酮均高于对照组（P0.01）；

Results It was revealed that the levels of testosterone , androstenedione and dehydroepiandrosterone sulfate were significantly higher in patients than those in the controls ( P 0.01 );

目的：比较雌激素与普拉睾酮（脱氢表雄酮，DHEA）对卵巢切除（OVX）的去势雌兔动脉粥样硬化形成的影响。

Objective : To compare the effects between estrogen and Prasterone ( Dehydroepiandrosterone , DHEA ) on improving atherosclerosis of ovariectomized rabbits .

目的探讨脱氢表雄酮（DHEA）对小鼠成骨细胞（OB）增殖周期与凋亡的调控作用。

Objective To investigate the effects of dehyroepiandrosterone ( DHEA ) on the proliferating cycle and apoptosis of mouse osteoblasts ( OB ) .

脱氢异雄酮对大鼠星形胶质细胞CD80、CD86和MHC-Ⅱ分子表达及其细胞增生影响的研究

Effects of Dehydroepiandrosterone on Expression of CD80 , CD86 and MHC - ⅱ Molecules on the Surface of Astrocytes and Astrocyte Proliferation

与上述内分泌轴想对应的部分内分泌激素包括外周睾酮水平、脱羟表雄酮（DHEA）及其硫酸盐（DHEA-S）、生长激素（GH）、胰岛素样生长因子（IGF）及褪黑素都趋于减少。

And parts of hormone , such as the testosterone , DHEA , DHEA-S , GH , IGF-1 and melatonin become less .

目的：研究动脉粥样硬化性血栓性脑梗死（ATCI）患者血清氧化低密度脂蛋白（OXLDL）、硫酸脱氢表雄酮（DHEAS）的变化及相关关系。

Objective : To investigate the changes of serum OX_LDL , DHEA_S in arteriosclerotic thrombotic cerebral infarction ( ATCI ) and their relationships .

目的了解脱氢表雄酮（DHEA）对老龄大鼠体重、记忆和免疫功能的影响。

Objective To study the effect of dehydroepiandrosterone ( DHEA ) on the weight , memory and immune function in older rats .

目的观察大鼠动脉一氧化氮（NO）信号途径的增龄性变化及脱氢表雄酮（DHEA）的干预作用。

Objective To observe age related changes of vascular nitric oxide signal pathways in rat and the dehydroepiandrosterone ( DHEA ) intervention effect .

目的观察脱氢表雄酮（DHEA）及其衍生物7羰基脱氢表雄酮（7oxoDHEA）对谷氨酸诱导的海马神经损伤的保护作用。

Aim To study Dehydroepiandrosterone ( DHEA ) and 7-oxo-dehydroepiandrosterone ( 7-oxo-DHEA ) protected hippocampal neurons against neurotoxicity induced by glutamate ( Glu ) .

游离睾酮（FT），硫酸脱氢表雄酮（DHEA-s），性激素结合球蛋白（SHBG）采用酶联免疫吸附法检测。

Free testosterone ( FT ), sex hormone binding globulin ( SHBG ) and dehydroepiandrosterone sulphate ( DHEA-s ) were measured by ELISA .

目的建立同时测定SD大鼠血浆中脱氢表雄酮（DHEA）、孕烯醇酮（PREG）和别孕烯醇酮（AP）的高效液相色谱质谱法。

Aim To establish a method for simultaneously determination of dehydroisoandrosterone ( DHEA ), pregnenolone ( PREG ) and allopregnenolone ( AP ) in rat plasma by HPLC / MS.

检测治疗前后BMI、血脂、外周胰岛素敏感度（SI）、FSH、LH、游离睾酮、硫酸脱氢表雄酮（DHEAS）、雄烯二酮、性激素结合球蛋白（SHBG）等指标。

The body mass index ( BMI ), blood fat , SI , FSH , LH , free testosterone , DHEAS , androstenedione and SHBG were examined before and after treatment .

提取卵泡液，测定卵泡液中睾酮、硫酸脱氢表雄酮（DHEAS）、雄烯二酮（A2）和胰岛素水平；

Extraction of follicular fluid and detection of testosterone ( T ), dehydroepiandrosterone sulfate ( DHEAS ), insulin ( INS ) and androstenedione ( A_2 ) were performed .