雄黄

雄黄对NB4和MR2细胞组织因子表达的影响

Effects of Realgar on Tissue Factor Expression of NB_4 and MR_2 Cells

结果：雄黄对MFC的抑瘤率为65.4%。

Results Inhibitory rates of Realgar on MFC were 65.4 % .

彗星试验检测雄黄对中国仓鼠肺细胞DNA的损伤作用

Impairing Effects on DNA in Chinese Hamster Lung Cells Induced by Realgar

纳米雄黄组与传统水飞雄黄组中砷的药代动力学参数经统计学分析均有显著差异（P0.05）。

There was a significant difference in pharmacokinetics parameters between nano-realgar group and traditional realgar group .

蒙药炮制法对雄黄主要成分及As2O3含量的影响

Effect of Mongolian medicine processing Methods on Main Constituents and As_2O_3 Content in Realgar

雄黄对NB4及HL-60细胞的促凋亡作用

Studies on red orpiment induction of NB 4 and HL-60 cell apoptosis

粉末冶金方法在块状雄黄制备过程As2O3气体污染防治中的应用

Application of powder metallurgical method in preventing and treating as_2o_3-containing gas pollution caused by the preparation of blocky Realgar

雄黄纳米微粒对人白血病细胞株HL-60的诱导分化作用

Differentiation of HL-60 cells induced by realgar nano-particles

ABC家族基因在乳腺癌耐药细胞MCF-7/ADM中的表达及雄黄对其作用初探

Expression of ABC gene family in mcf-7 / adm cell line and the reversal effect of Realgar on these genes

结论：低浓度雄黄对HL-60细胞具有诱导分化作用。

Conclusion : Low dose realgar induces differentiation in human acute myeloid leukemia cell line HL-60 .

雄黄对T淋巴细胞白血病细胞系CEM的促凋亡作用

Study on Realgar inducing apoptosis in T lymphocytic cell line CEM

雄黄对Raji细胞凋亡的影响

Effect of Realgar on Apoptosis in Raji Cells

纳米雄黄组在达峰时间、峰浓度、AUC等方面明显优于传统雄黄组。

Tmax , Cmax and AUC in nano-realgar group were better than traditional realgar group obviously .

方法：经雄黄处理后的哮喘豚鼠肺泡灌洗液中嗜酸细胞为研究对象，嗜酸细胞凋亡的形态学观察采用Giemsa染色法和电子显微镜。

METHODS : The morphology of apoptosis of eosinophils was observed by Giemsa staining and electron microscope .

目的了解雄黄治疗急性早幼粒细胞白血病（APL）的机制。

Objective To further understand the possible mechanism of realgar in the treatment of acute promyelocytic leukemia ( APL ) .

在一定范围，其作用随时间和浓度增加而增强。雄黄是复方青黛片治疗APL取得高缓解率的中药成分。

And the red orpiment is responsible for the high CR rate of APL induced by the composite indigo naturalis tablets .

结果以剂量1.0g／kg诱发雄性小鼠的微核率显著高于阴性对照，P＜0.01，而且随着雄黄剂量增加，骨髓嗜多染红细胞的微核率升高。

The results showed that xiong huang more than 1.0g/kg dose could induce male mice marrow micronucleus rates increase ( P < 0 01 ), dous effect was found .

这些标型特征不仅有助于南华砷铊矿床进一步开发，而且有助于含雄黄的热液矿床，特别是As、Hg、Tl、Sb、Au等矿床的找矿勘探。

All these typomorphic characteristics are helpful for the further development of the Nanhua As-Tl deposit , but also for prospecting of realgar-bearing hydrothermal deposits , especially those of As , Hg , Tl , Sb , Au , etc.

目的：研究复方青黛片的主要成分雄黄治疗急性早幼粒细胞白血病（APL）的机制。

Objective : To study the possible mechanism of red orpiment , which is main component of composite indigo naturalis tablets , in the treatment of acute promyelocytic leukemia ( APL ) .

结论：下调NB4和MR2细胞TF的表达并降低其PCA可能是雄黄改善APL患者弥散性血管内凝血（DIC）早期出血症状的主要机制之一。

Concluson : Down-regulating TF expression and PCA of NB_4 and MR_2 cells by Realgar may be one of the mechanism of its improvement effect on DIC-related hemorrhage of APL patients .

目的探讨阿霉素耐药乳腺癌细胞系MCF7/ADM的ABC家族基因的表达及其与敏感细胞系MCF7/S的差异，观察中药雄黄对ABC膜转运蛋白超家族中各基因（mdr1、mrp、bcrp）表达的影响。

Objective To study the expression of ABC gene family of MCF 7 / ADM cells as compared to parental cell line MCF 7 / S , and its reversion by realgar of the expressed genes .

目的探讨硫化砷（雄黄As4S4，雌黄As2S3）对MR2细胞（维甲酸耐药的急性早幼粒细胞白血病细胞株）促凝活性（PCA）和组织因子（TF）表达的影响。

Objective To investigate the effect of arsenic sulfide on procoagulant activity ( PCA ), tissue factor expression and tissue factor mRNA transcription in ATRA resistant acute promyelocytic leukemia ( APL ) cell line & MR2 cell .

目的：探讨雄黄（As4S4）纳米微粒对于人急性早幼粒白血病细胞HL-60的抑制增殖和诱导分化作用。

Objective : To investigate the proliferation inhibition and the differentiation effects of realgar ( As_ ( 4 ) S_ ( 4 )) nano-particles on human acute myeloid leukemia cell line HL-60.Method : Cell viability was determined by MTT and PI-stained cell cycle assays .

粉防己碱对雄黄中毒大鼠尿砷血砷含量的影响

Effect of tetrandrine on arsenic content in rats with realgar poisoning

石门雄黄矿地区居民砷暴露研究

Arsenic exposure of residents in areas near Shimen arsenic mine

纳米雄黄脂质体的制备、特性检测和体外抗肿瘤细胞作用的研究

Preparation and characterization of realgar nano-liposome and its antitumor effect in vitro

雄黄中的砷及其代谢物在大鼠体内的排泄动力学研究

Excretion of arsenic in realgar and its metabolites in rats

雄黄诱导肿瘤细胞凋亡的实验研究

Experimental study of inducing effect of Realgar on tumor cells

中国雄黄雌黄矿床类型、成矿机制与找矿方向

Deposit types of Chinese realgar / orpiment deposits and their mineralizing machanisms

中国雄黄雌黄矿床主要类型及其地质特征

Geological characteristics and major types of Realgar and orpiment deposit of China