重症联合免疫缺陷

目的探讨重症联合免疫缺陷病（SevereCombinedImmunodeficiency，SCID）的临床病理特征。

Purpose To explore the clinicopathological features of severe combined immunodeficiency ( SCID ) .

同时，SOC通道功能的异常也与一些疾病相关，比如重症联合免疫缺陷综合症等。

Meanwhile , SOC can be related to some diseases like severe combind immunodeficiency .

在医学上，这种情况称为X连锁重症联合免疫缺陷（X-SCID）。

Medically , the condition is called X-linked Severe Combined Immunodeficiency ( X-SCID ) .

目的探讨在重症联合免疫缺陷（SCID）鼠体内建立腹膜后荷人卵巢癌动物模型的可行性。

Objective To establish retroperitoneal transplantation model of human ovarian carcinoma in severe combined immunodeficiency ( SCID ) mice .

前言：目的：建立人M5型白血病细胞系SHI-1/SCID（重症联合免疫缺陷）小鼠模型，探讨白血病细胞的接种密度与SCID小鼠成瘤率及病理变化的关系。

AIM : To establish a model of human M5 leukemia and investigate the pathomorphological change in severe combined immunodeficient ( SCID ) mice after being transplanted with SHI-1 cells .

非肥胖型糖尿病/重症联合免疫缺陷性小鼠（NOD/SCID）皮下注射MSC，病理切片检测第30d细胞体内成瘤性。

MSC were subcutaneous injected into the human-nonobese diabetes / severe combined immunodeficiency disease ( NOD / SCID ) mice and carcinogenesises of the MSC in vivo were detected by pathological diagnosis .

目的：建立稳定表达增强型红色荧光蛋白（ERFP）的NOD/SCID-hu（非肥胖性糖尿病/重症联合免疫缺陷）小鼠前列腺癌骨转移模型。

Objective : To establish a stable prostatic carcinoma osseous metastasis NOD / SCID-hu mouse model expressing enhanced red fluorescent protein ( ERFP ) .

目的：从孕4.5~6周的人胚胎肝脏中分离培养肝干细胞，并观察其在重症联合免疫缺陷（SCID）小鼠损伤肝脏中的植入。

Objective : To separate hepatic stem cells from human fetal livers of 4.5-6-week gestation and observe their engraftment into injured livers of mice with severe combined immunodeficiency ( SCID ) . Methods : Stem cells isolated from human fetal livers were long-term cultured in vitro .

目的研究人胎儿血造血干/祖细胞（HSPC）的生物学特性并对其进行非肥胖糖尿病/重症联合免疫缺陷（NOD/SCID）小鼠移植。

[ Abstract ] Objective To study the biological features of human fetal blood hematopoietic stem / progenitor cells ( HSPC ), and their capacity of hematopoietic reconstitution in non-obese diabetic / severe combined immunodeficiency disease ( NOD / SCID ) mice .

人正常子宫颈移行上皮重症联合免疫缺陷小鼠模型的建立

Establishment of animal model of human cervical tissue in SCID mice

人脐血程序移植重症联合免疫缺陷小鼠的实验研究

Preliminary study on human cord blood scheduled transplantation in severe combined immunodeficient mice

重症联合免疫缺陷者的长期生存：母体移植物的长期作用

Long-term survival in severe combined immune defi-ciency : The role of persistent maternal engraftment

人胎肝干细胞在重症联合免疫缺陷小鼠损伤肝脏中的植入

Engrafting human fetal liver stem cells into injured livers of mice with severe combined immunodeficiency disorder

重症联合免疫缺陷病临床病理分析

Clinicopathological analysis of severe combined immunodeficiency

同时也有人以基因工程改良干细胞，以矫正例如重症联合免疫缺陷的遗传缺失。

They are also genetically engineering stem cells to correct genetic disorders such as severe combined immunodeficiency .

研究结果1.成功建立于糖尿病抵抗/重症联合免疫缺陷（NOD/SCID）小鼠异体移植动物模型。

Successfully established resistance in diabetic / severe combined immunodeficiency ( NOD / SCID ) mouse xenograft animal model . 2 .

例如再生障碍性贫血、重症联合免疫缺陷和血红蛋白病等血中缺乏特定的免疫细胞。

Aplastic anemia , severe combined immunodeficiency and hemoglobin disorders , for example , involve deficiencies of specific immune cells in the blood .