远志

太行山中部野生远志分布与岩石相关性研究

Study on the Correlation between the Distribution of Wild Polygala tenuifolia and Rock in the Central Part of Taihang Mountains

用简单重复序列区间（ISSR）分子标记对中药原植物远志和西伯利亚远志的野生居群及远志的栽培居群进行了遗传多样性分析。

In the present study ISSR ( inter-simple sequence repeat ) molecular markers were employed to investigate the genetic diversity within and among wild populations of Polygala tenuifolia and P. sibirica and cultivated populations of P. tenuifolia .

HPLC法测定远志流浸膏中远志酸的含量

Determination of Polygalacic Acid in Extractum Polygalae Liquidum by HPLC

方法：以HPLC法、可见分光光度法测定远志中远志皂苷元和远志总皂苷元的含量。

Methods : To determine the contents of effective compositions by HPLC , VIS spectrophotometry and UV spectrophotometry ;

体内试验中，远志皂苷可在一定程度上提高AD大鼠学习记忆能力，减轻Ap1-40对脑神经细胞产生的毒害作用。

In vivo , TEN can reduce nerve cells toxicity to improve learning and memory capacity in AD rats induced by A β 1-40.5 .

远志总皂苷对AD模型大鼠学习记忆及海马AchE、ChAT活性的影响

Effect of saponins of polygala on learning , memory and activities of AchE and ChAT in hippocampus in AD Rats

采用TLC的方法分别对比了生远志和蜜远志化学成分的异同。

The chemical constituents of the crude and the prepared were studied and compared by TLC method .

结果表明，TF能透过大鼠血脑屏障到达脑组织而发挥神经生物活性，说明TF很可能是远志皂苷水解物益智作用的有效成分。

It indicated that TF could pass through blood-brain barrier and played neural activity in rats .

采用GC-MS法对单味药远志、石菖蒲和对药远志-石菖蒲中的挥发油及脂溶性成分进行鉴定。

The liposoluble components and volatile oil of RP , RAT and matched pair of them were identified by GC-MS.

PAS反应对多糖的组织化学定位结果显示在两种远志根的次生韧皮部和周皮中都有多糖物质的积累。

PAS reaction results showed polysaccharide were also existed in root periderm and secondary phloem of the two plants .

GC／MS分析表明，远志挥发油中含有多种活性成分，如alpha-细辛醚、甲基丁香酚、棕榈酸等。

The results from GC / MS analysis show that the volatile oil from radix Polygalae has multiple active constituents , such as Alpha-ether , methyl eugenol , Palmitic acid of asarum .

得到以下主要结论：①CO2超临界法萃取远志挥发油收率高，可有效避免水蒸气蒸馏法所造成的对有效成分的影响。

The following main conclusions have been drawn : ① CO2supercritical method has high extraction yield of volatile oil from radix polygalae , which can primely avoid the impact of distillation by steam on effective compositions .

蜜炙远志调控胃肠Cajal间质细胞及其关联机制的研究

Study on the Regulating Effect of Honey-stir-baked Radix P. on the Interstitial Cells of Cajal in Gastrointestinal Tract and Its Correlated Mechanism

目的：建立阿尔茨海默病（AD）的大鼠模型，并观察远志皂苷对AD模型大鼠β-淀粉样蛋白（Aβ）沉积及其神经细胞毒性的影响。

Objective : To establish an animal model of Alzheimer 's disease ( AD ) and to observe the therapeutic effect of tenuigenin ( TEN ) on deposition of β - amyloid protein ( A β) and its neurotoxicity .

结论：远志的合理栽培密度为亩留苗11.1万株，株行距20cm×3cm。

Conclusion : The proper planted density is 20 cm × 3 cm , i. e. 111 thousand plants per mu .

结论生远志抑制胃肠运动及损伤黏膜机制与其降低胃组织PGE2含量与Ca2+-ATP酶活力，增加NO含量相关；

Conclusion The mechanism of crude Radix Polygalae could restain gastrointestinal motility and damage mucosa is related to decreasing PGE2 and Ca2 + - ATPase and increasing NO.

以远志酸（Polygalicacid）为对照品，对远志药材的定性、定量分析方法进行了研究。

It was first isolated from Radix Polygalae ( Yuanzhi ) . Using polygalic acid as a standard substance , quality standard of Radix Polygalae ( Yuanzhi ) was studied .

确定了远志提取纯化工艺条件：药材用10倍量60%乙醇回流提取2次，每次2.5h。

The optimum conditions of extraction process were 60 % ethanol , 2.5 hours for reflux , 10-fold solvent and 2 times for extraction .

方法：采用急性毒性LD50法、胃排空甲基橙比色法及小肠炭末推进法，对比远志不同蜜炙品与生品对小鼠全身毒性及胃肠靶器官的毒性。

Methods and results : Using LD_50 of acute toxicity , methyl orange colorimetry of gastric emptying and charcoal propulsion of small intestine , to research the mice 's general and target organ toxicity on stomach and intestines between Crude and Honey-stir-baked Radix Polygalae .

降压1号颗粒由制水蛭4.5g，远志6g，决明子12g，巴戟天15g，葛根15g，川芎10g，泽泻10g等药物组成，由本院制剂室制备。

The No. 1 Grain produced in the agent room was constituted by 4.5 g leech , 6 g milkwort , 12 g cassia seed , 15 g morinda , 15 g puerarin , 10 g Szechwan lovge rhizome and 10 g waterplantain rhizome , etc. The No.

目的探讨远志的抗衰老机制。

Objective To study the antiaging mechanism of Polygala tenuifolia Wild .

远志化学成分和药理活性的研究进展

Advances in Study on Chemical Constituents and Pharmacological Activities of Polygala

液相色谱-串联质谱法对小鼠血浆中远志皂苷元的测定

Determination of Senegenin in Mouse Plasma by Liquid Chromatography-Tandem Mass Spectrometry

远志总苷对快速老化模型（SAM-P/8）小鼠学习记忆能力的作用及其机理研究

The effect and mechanism of Polygala tenuifolia glycoside on sam-p / 8

目的：研究远志皂苷的提取分离及鉴定方法。

Objective : Study on the method of isolation and identification onjisapomin .

环境因子与远志药材质量相关性分析

Correlation between Environmental Factors and the Quality of Radix Polygalae

远志种子繁殖实验观察

Observation on the Propagating Experiment of Polygala tenuifolia Willd Seed

远志需肥特性研究

Study on fertilizer requirement characteristics of Polygala tenuifolia Willd

远志种子质量分级标准研究

Studies on Grading Standard of Polygala Tenuifolia Willd Seed

目的：研究晋产远志皂苷元含量。

Objective : To study the senegenin content in Radix Polygalae from Shanxi .