过氧化物酶体增殖物激活受体

  • 网络Peroxisome proliferator activated receptor;PPAR-;ppar;ppars;ppar-γ;ppara
过氧化物酶体增殖物激活受体过氧化物酶体增殖物激活受体
  1. 代谢综合征中医分型及与过氧化物酶体增殖物激活受体-γ的关系

    The Patterns of Metabolic Syndrome in TCM and its Relationship with PPAR - γ

  2. 茶多酚对酒精性肝病过氧化物酶体增殖物激活受体α及核因子-κB的调节作用

    Regulatory Effects of Tea Polyphenols on Peroxisome Proliferator-Activated Receptor α and Nuclear Factor - κ B in Alcoholic Liver Disease Models

  3. 罗格列酮对日本血吸虫病肝纤维化小鼠肝组织核因子-κB和过氧化物酶体增殖物激活受体γ表达的影响

    Effect of rosiglitazone on the activity of hepatic nuclear factor-kappa B and expression of peroxisome proliferator-activated receptor - γ in mice with liver fibrosis due to schistosoma japonicum infection

  4. 目的在大肠杆菌中表达过氧化物酶体增殖物激活受体γ共激活因子-1(PPARγC1)与谷胱甘肽-S转移酶(GST)的融合蛋白,并制备抗PPARγC1的多克隆抗体。

    Objective To express the fusion protein of glutathione S-transferase ( GST ) and peroxisome proliferator-activated receptor-gamma coactivator-1 ( PPAR γ C1 ) in E.

  5. 目的:观察溃疡性结肠炎(Ulcerativecolitis,UC)大鼠肠黏膜中过氧化物酶体增殖物激活受体γ(PPARγ)的表达。

    Objective : To observe the expression of the peroxisome proliferators_ activated receptor γ( PPAR γ) in colonic mucosa of rat with ulcerative colitis ( UC ) .

  6. 化疗药物联合过氧化物酶体增殖物激活受体(PPAR)的配体能够协同抑制肺细胞癌及卵巢癌细胞。

    Chemotherapy given in combination with ligands for the peroxisome proliferator-activated receptor - ( PPAR ) synergistically inhibits the growth of lung and ovarian cancer cell lines .

  7. 目的:观察日本血吸虫病肝纤维化小鼠肝脏肝组织核因子-κB(NF-κB)的活性和过氧化物酶体增殖物激活受体γ(PPARγ)的表达,及PPARγ配体罗格列酮对其表达的影响。

    AIM : To investigate the effect of rosiglitazone on the binding activity of hepatic nuclear factor-kappa B ( NF - κ B ) and the expression of peroxisome proliferator-activated receptor gamma ( PPAR γ) in mice with liver fibrosis caused by schistosoma japonicum infection .

  8. 研究背景和目的:过氧化物酶体增殖物激活受体(PPARs)是一类由配体激活的核转录因子,属于核内受体超家族成员。

    Background and Objective : Peroxisome proliferator-activated receptors ( PPARs ) are a class of ligand-activated nuclear transcription factor belonging to the nuclear receptor superfamily .

  9. 目的:用贵州小香猪建立动脉粥样硬化(As)动物模型,探讨该模型中B类I型清道夫受体(SR-BI)和过氧化物酶体增殖物激活受体γ(PPARγ)表达的变化。

    Aim : To study the expressions of scavenger receptor class B type I ( SR-BI ) and peroxisome proliferator-activated receptor γ( PPAR γ) in atherosclerotic mini swine and provide a new mechanism for investigating the pathogenesis of atherosclerosis .

  10. 目的探讨过氧化物酶体增殖物激活受体-γ(PPAR-γ)经其配体吡咯列酮(pioglitazone,PGZ)激活后,对胆管癌细胞体外侵袭力的影响及机制。

    Objective To explore the effect and mechanism of ligand pioglitazone ( PGZ ) activating PPAR - γ on the invasiveness of cholangiocarcinoma cell in vitro .

  11. 目的:观察化痰活血方对高脂血症大鼠肝脏过氧化物酶体增殖物激活受体α(PPARα)、乙酰辅酶A氧化酶(ACO)表达的影响。

    Objective : To observe effects of Huatan Huoxue Prescription on expressions of peroxisome proliferation substance activating receptor α ( PPAR α) and the target gene acetyl-CoA oxidase ( ACO ) in the liver of the rat with hyperlipemia .

  12. 双位点夹心酶联免疫法检测不同海拔和不同高原暴露时间下内皮PAS蛋白、PHD蛋白、过氧化物酶体增殖物激活受体α、促红细胞生成素和血管内皮细胞生长因子在血液和组织中的表达。

    Enzyme-linked Immunity assays to detect different altitudes and different altitude exposure time for the differences of endothelial PAS protein , PHD protein , peroxisome proliferator-activated receptor a , erythropoietin and vascular endothelial growth factors expression in rats ' blood and tissues . Results : 1 .

  13. 目的探讨人过氧化物酶体增殖物激活受体γ辅助激活因子-1α(PGC-1α)基因Thr394Thr/Gly482Ser联合多态性与2型糖尿病相关关系。

    Objective To investigate the association between Thr394Thr / Gly482Ser variants of peroxisome proliferator-activated receptor gamma coactivator-1 ( PGC-1 ) gene and type two diabetes mellitus ( type 2 DM ) in Chinese population .

  14. 近年来,随着对调控脂肪细胞分化的关键转录因子&过氧化物酶体增殖物激活受体γ2(PPARγ2)研究的不断深入,发现其在骨代谢过程中可能扮演着关键的角色。

    For the past few years , along with the increasingly deep investigation of Peroxisome proliferator-activated receptor gamma 2 ( PPAR γ 2 ) & which is the key transcription factor of adipocyte differentiation , we found it may be playing a important role in bone metabolism process .

  15. 目的构建高效表达人过氧化物酶体增殖物激活受体δ(hPPARδ)的真核表达载体,为hPPARδ受体功能和基于hPPARδ受体靶点的药物筛选提供分子研究平台。

    Objective To construct a highly efficient eukaryotic expression vector carrying human peroxisome proliferator-activated receptor δ( hPPAR δ) gene in order to provide an ideal molecular platform for screening natural ligands and functional study of hPPAR δ .

  16. 结论:过氧化物酶体增殖物激活受体γC161→T的置换与冠状动脉粥样硬化性心脏病之间有重要的相关性,T等位基因携带者发生冠状动脉粥样硬化性心脏病的危险性较少。

    CONCLUSION : There is an important correlation between the substitution of PPAR γ C161 → T and CAHD , and " T " allele carriers demonstrate a lower risk of CAHD .

  17. 大鼠缺血再灌注心肌过氧化物酶体增殖物激活受体α的表达及血清游离脂肪酸含量的变化

    Expression of peroxisome proliferator-activated receptor α in myocardial ischemia reperfusion rats

  18. 配体活化的过氧化物酶体增殖物激活受体γ诱导结肠癌细胞凋亡

    Activation of Peroxisome Proliferator-Activated Receptor Gamma Induces the Apoptosis in Human Colon Cancer Cells

  19. 缺氧/复氧损伤对大鼠海马神经元过氧化物酶体增殖物激活受体γ表达的影响

    Expression of peroxisome proliferator-activated receptor γ in hippocampus neurons in rats after oxygen deprivation / oxygen supply in vitro

  20. 患多囊卵巢综合征的中国妇女过氧化物酶体增殖物激活受体γ和共活化物1α基因的多态性

    Polymorphisms of the peroxisome proliferator-activated receptor - γ and its coactivator-1 α genes in Chinese women with polycystic ovary syndrome

  21. 亚低温对局灶性脑缺血再灌注大鼠过氧化物酶体增殖物激活受体γ表达的影响

    The Effects of Mild Hypothermia on the Expression of Peroxisome Proliferator-Activated Receptor γ in Rats Brains after Focal Cerebral Ischemia and Reperfusion

  22. 急性心肌缺血损伤中过氧化物酶体增殖物激活受体α活化与肿瘤坏死因子α表达的关系

    Relationship between the activation of peroxisome proliferate-activated receptor alpha and the expression of tumor necrosis factor alpha in acute myocardial ischemic damage

  23. 小鼠过氧化物酶体增殖物激活受体γ1高表达对游离脂肪酸介导的β细胞损害的保护作用

    The protective effect of high expression of mouse peroxisome proliferator activated receptor γ _1 on free fatty acid induced β cell impairment

  24. 过氧化物酶体增殖物激活受体γ在缺氧缺血性神经细胞死亡中的作用

    Effect of peroxisome proliferation activated receptor - γ on neuronal cell death induced by hypoxia and ischemia in rats in vitro and in vivo

  25. 目的研究缬沙坦对兔主动脉过氧化物酶体增殖物激活受体-γ(PPAR-γ)表达的影响,探讨其抗动脉硬化(AS)的可能机制。

    Objective : To study the effect of valsartan on the expression of peroxisome proliferator-activated receptor - γ ( PPAR γ) in rabbit aorta , and investigate the possible anti-atherogenic mechanism of valsartan .

  26. 目的观察预先应用过氧化物酶体增殖物激活受体α的激动剂非诺贝特活化过氧化物酶体增殖物激活受体α,对急性心肌缺血性损伤大鼠血清肿瘤坏死因子α的影响。

    AIM : To observe the activation of peroxisome proliferate-activated receptor α( PPAR α) by fenofibrate of agonists of PPAR α after pre-application , and the effects on tumor necrosis factor alpha ( TNF - α) in acute myocardial ischemic damage rats .

  27. 胃缺血再灌注损伤与活性氧、白细胞、胃酸、胃黏液、一氧化氮、环氧合酶、过氧化物酶体增殖物激活受体γ等因素密切相关。

    The mechanism of gastric ischemia reperfusion injury ( GIRI ) may be related to many factors , such as reactive oxygen species ( ROS ), nitric oxide ( NO ), polymorphonuclear leukocytes ( PMN ), Gastric acid and mucus , cyclooxygenase and peroxisome proliferator-activated receptor γ .