起搏细胞

进行细胞移植后建立的房室传导阻滞动物模型可证实窦房结起搏细胞有一定的作用。

The atrioventricular block animal model after cell transplantation can confirm that the sinoatrial node pacemaker cell can work effectively .

根据培养细胞形态结构观察与电生理检测，长梭形细胞符合窦房结起搏细胞的特点。

According to the form and structure 's view and electrophysiology detection of the cultured cell , macrospindle cell consistents with the feature of sinoatrial node pacemaker cell .

结果心传导系统的P细胞（起搏细胞）肿胀、变形，胞质内线粒体肿胀、空泡化。

Results There were swelling and deformation of pacemaker cells ( p cells ) and mitochondrial swelling and vacuolization in cardiac conduct system .

大量研究表明，窦房结起搏细胞舒张期自动除极化过程虽有多种跨膜离子流参与，但起主要作用的是起搏离子流（If）。

Lots of study revealed that spontaneous depolarization of sinoatrial cell included many kinds of transmembrane ionic currents . the Funny Curret ( If ) was the most important one .

Cajal间质细胞（ICC）是胃肠道的电起搏细胞。

The interstitial cells of Cajal ( ICC ) are the pacemaker cells in the gastrointestinal tract .

结论ICC是胃平滑肌运动的起搏细胞。胃动素通过ICC对胃肌收缩进行调节。

Conclusion The pacemaker cells of the contractile activity of gastric smooth muscle cells are ICC , Motilin regulates the gastric smooth muscle contraction initiated by ICC .

ICC作为胃肠运动自主节律性的起搏细胞已得到广大研究者的承认，但这种自主节律性的产生机制仍不清楚。

Interstitial Cells of Cajal ( ICC ) in the gastrointestinal ( GI ) tract were considered to be pacemaker cells for GI movement , but the generating mechanism is not well known yet .

结果KIT染色阳性，形态与胃肠道起搏细胞ICCs相似的细胞（ICCs样细胞）存在于豚鼠全泌尿道的黏膜下层和肌层。

Results Cells with positive staining by KIT and with similar morphology to ICCs were found in the submucosal and muscular layers of the entire urinary tract of guinea pigs .

采用ICC特异鉴定方法――KIT免疫组织化学染色，KIT阳性、形态与胃肠道ICC相似的ICC样细胞被证实存在于豚鼠和人的膀胱，且推测其可能就是膀胱的起搏细胞。

KIT immunohistochemistry can identify ICC specifically . ICC-like cells which are KIT immunostaining positive and have the semblable morphology with ICC have been found in the guinea pig and human bladder . They were thought the good candidate for bladder pacemaker cells .

根据上述结果，似可认为，ET－1与ET＿A受体的结合可激活K＿（ATP）通道，致使K￣＋电流增加和起搏细胞的VDD减慢。

On the basis of above results , it appears that the binding of ET-1 with ET_A receptor may induce an activation of K_ ( ATP ) channels with resultant increase in K ￣ + current so as to decrease the velocity of diastolic depolarization in the pacemaker cells .

目的研究莫索尼定（Mox）对窦房结起搏细胞是否具有电生理作用及其相关受体以探讨Mox治疗实验性心律不齐的机理。

AIM To explain the mechanism of moxonidine ( Mox ) in treatment of experimental arrhythmia by studying whether Mox has the electrophysiologic effects on sinoatrial node ( SAN ) pacemaker cells and which are its related receptors .

目的：研究关附乙酯（DGFA）对窦房结起搏细胞电生理学的影响。

AIM : To study the electrophysiological effects of diacetyl guan-fu base A ( DGFA ) on pacemaker cells in sinoatrial ( SA ) node .

内皮素对家兔窦房结起搏细胞电活动的影响

Effects of endothelin on the electrical activity of sino-atrial pacemaker cells of rabbit

膀胱起搏细胞初探

An Initial Research on the Bladder Pacemaker Cells

随年龄递增，其间质（胶原纤维为主，及脂肪组织、弹力纤维和网状纤维）逐渐增多，而主质细胞（起搏细胞、移行细胞）相对减少；

There are increasing in collagen , elastic fibers and fatty tissue with aging .

急性缺血对单个家兔窦房结起搏细胞钙通道的影响

Effects of acute ischemia on calcium channels in isolated rabbit sino-atrial node pacemaker cells

钙通道阻断剂对家兔起搏细胞自发活动的作用

Effects of the Calcium Current Channal Blockers on Spontaneous Activity of Rabbit Pacemaker Cells

高频驱动期间和驱动停止后，优势起搏细胞跨膜电位幅度减小。

The amplitude of the transmembrane potential was reduced during and after high frequency drive .

离体兔心窦房结起搏细胞跨膜电位的引导

The recording of the transmembrane potential of the pacemaker cells in the isolated rabbit sinus node

异丙肾上腺素调节窦房结起搏细胞延迟整流钾通道信号传递机制的研究

Study on the Signal Transmit Mechanism of β - acceptor Agonist-Isoprenaline Regulating Sinus P-cell Delayed Rectifier Potassium Channels

若干天后，动物体内的一些心脏细胞就会开始像起搏细胞一样运作。

A few days later , some of the heart muscle cells in the animals began to act like pacemaker cells .

他们发现他们可以使用化学物质钾使豚鼠正常的心脏细胞担任起起搏细胞的角色。

They found they could use the chemical potassium to trick normal heart cells in guinea pigs to act like pacemaker cells .

其中梭形细胞最多，且形态结构与电生理特征符合窦房结起搏细胞的特点。

The greated proportion of cells were spindle cells whose configuration , structure and electrophysiological characteristics accorded with that of pacemaker cell of SAN .

但由于干细胞定向诱导分化技术尚不成熟，且分离及纯化起搏细胞亦有相当难度，单纯的细胞生物起搏研究进展缓慢。

Biological cell therapy improved slowly because of the amature directional inducement for stem cells and the difficulty of isolation and purification of pacemaker cells .

生理条件下，在体膀胱可记录到起源于膀胱顶，向膀胱颈方向传播的自发性、规律性慢波，推测在膀胱顶存在有起搏细胞；

Under physiological condition , spontaneously and regularly occurring slow waves which are propagated caudad from the dome toward the trigone , can be recorded in the bladder in vivo .

起搏细胞一般位于组织块的中央，细胞为圆形或多边形，胞核大，胞质少呈亮区。

P - cells , usually in the central protion of the mass of tissues , were round or polyhedral and had little cytoplasm with a disproportionately large central nucleus .

结果：①在窦房结的培养中，起搏细胞、过渡细胞、和心房肌细胞都存在，起搏细胞的比例是评价培养方法的重要指标。

RESULTS : ① In the culture of sinoatrial node , pacemaker cells , transitional cells and myocardial cells all existed , and the proportion of pacemaker cells was the important marker for evaluating the culture method .

差速贴壁结合5-溴脱氧尿核苷处理的纯化培养的窦房结细胞梭形细胞电生理特征符合窦房结起搏细胞的特点，即动作电位有舒张期自动去极化。

The electrophysiological characteristic of the sinoatrial node fusiform cells purified by the differential velocity adherent technique combined with 5 ' bromo 2 ' deoxyuridine treatment was in accordance with that of sinoatrial node pacemaker cells , that was , action potential had diastolic spontaneous depolarization ;

生物昼夜起搏系统细胞与分子机制研究进展

Progress in biological pacemaker system cellular and molecular mechanisms

快速心房起搏可导致细胞内钙离子超载。

RAP can induce calcium overload in atrial myocyte .