血管钙化

体外血管钙化模型中骨钙素的分泌和X型胶原的表达

Osteocalcin secretion and the expression of type X collagen mRNA in an in vitro model of vascular calcification

已有研究表明活性氧物种（ROS）促进血管钙化形成。

Researches have shown that reactive oxygen species ( ROS ) promote the formation of vascular calcification .

辛伐他汀能抑制主动脉MMP-2的表达，并且随着MMP-2表达程度的降低，主动脉钙化程度也有所改善。结论MMP-2表达与钙代谢及血管钙化密切相关。

CONCLUSION MMP-2 expression is correlated with calcium metabolism and artery calcification .

MMP-2表达与大鼠动脉粥样硬化和血管钙化的关系及辛伐他汀对其影响

Relation between expression of MMP-2 and artery calcification in rats , and the effect of Simvastatin

目的在体外血管钙化模型基础上探讨同型半胱氨酸（HCY）对血管钙化的影响。

Objective To explore internal relation between homocysteine ( HCY ) and cardiovascular ectopic calcification in vitro .

PiT-1在高磷血症导致慢性肾衰竭大鼠血管钙化中的表达

Expression of PiT-1 in hyperphosphatemia induced arterial calcification in chronic renal failure rats

本文旨在观察钙化细胞血红素加氧酶（HO）-一氧化碳（CO）-环磷酸鸟苷（cGMP）系统的改变，以探讨血管钙化发生的细胞分子机理。

To investigate the changes in heme oxygenase ( HO ) carbon monoxide ( CO ) cyclic guanosine monophosphate ( cGMP ) pathway in calcified rat vascular smooth muscle cells ( VSMCs ) .

结论辛伐他汀能降低血管钙化组织中BMP-2表达，这可能是辛伐他汀对血管钙化具有保护作用的因素之一。

Conclusion ( Simvastatin can ) reduce the expression of bmp-2 in calcified vessels . It may attribute to the beneficial effect of simvastatin on protecting vesels .

结果病理学观察显示，成功建立VitD3诱发的血管钙化模型。结论提示DSP通过减少大鼠动脉钙化组织中OPG的表达，有效抑制血管钙化。

Results The model of vascular calcification and osteoporosis induced with VitD_ ( 3 ) was stablished . Conclusion The study proves that DSP can inhibit vascular calcification effectively with decreasing OPG expression in vessels .

方法建立大鼠血管钙化模型（维生素D3加尼古丁，VDN），将40只大鼠分为4组：A组（对照组）；

Methods Rat model of vascular calcification was established by in injection of vitamin D 3 plus intragastric administration of nicotine ( VDN ) .

方法：利用维生素D3（VitaminD3）和尼古丁（nicotine）制备大鼠血管钙化模型，检测血管钙含量、碱性磷酸酶（ALP）活性、45Ca摄入和血管骨钙素含量；

Methods : Vascular calcification model was established in rats by using vitamin D 3 and nicotine . Vascular calcium content , alkaline phosphatase ( ALP ) activity , 45 Ca uptake and the content of osteocalcin in vessels were measured .

方法用维生素D3加尼古丁诱导大鼠血管钙化模型，并给以高蛋氨酸饮食六周诱导大鼠高同型半胱氨酸血症，用高效液相色谱法检测血浆总同型半胱氨酸（Hcy）水平；

Methods : Arterial calcification of Sprague Dawley rats was induced by vitamin D 3 plus nicotine . Hyperhomocysteinemia was established by feeding high methionine diet for six weeks and was assessed by plasma total homocysteine ( tHcy ) level detected by HPLC method .

方法采用维生素D3肌注和尼古丁灌胃诱导大鼠血管钙化，VOnKossa染色、钙含量测定、45Ca2+沉积及碱性磷酸酶（ALP）活性测定判断血管钙化程度，同时测定血液流变学指标的变化。

Method : The vascular calcification model of rat was induced by administration of vitamin D_3 plus nicotine . Estimating the extent of calcification were assayed by Von Kossa staining and calcium content , 45 Ca 2 + deposition and alkaline phosphatase activity determination .

脂联素基因敲除小鼠血管钙化的研究

Study on Development and Mechanism of Arterial Calcification in Adiponectin-deficient Mice

众所周知老年患者发生骨质疏松的同时常常伴发血管钙化。

Osteoporosis is usually occur concomitantly with arterial calcification in elderly .

在慢性肾脏病中控制血清磷可能减少血管钙化

Serum Phosphate Control May Reduce Vascular Calcification in Chronic Kidney Disease

血管钙化时血管血红素加氧酶/一氧化碳系统的变化

Changes of heme oxygenase-carbon monoxide system in vascular calcification in rats

辛伐它汀对血管钙化组织中骨形成蛋白-2表达的影响

Effect of Simvastatin on Expression of BMP-2 in Calcified Vessels

2型糖尿病大鼠模型血管钙化及相关因素分析

Vascular Calcification in Rat Models of Type 2 Diabetic Nephropathy

骨钙素及Ⅰ型胶原在体外血管钙化细胞中的表达

Expression of osteocalcin and collagen ⅰ in vitro model of vascular calcification

辛伐他汀促骨形成，使骨钙在骨组织沉积增加的同时减轻血管钙化程度。

Simvastatin can promote bone formation and reduce vascular calcification .

外源性硫化氢对大鼠血管钙化的影响

Effect of exogenous hydrogen sulfide on vascular calcification in rats

同型半胱氨酸对大鼠血管钙化模型的影响

Effects of homocysteine on rat model of vascular calcification

高同型半胱氨酸血症促进大鼠血管钙化

Promoting effect of hyperhomocysteinemia on vascular calcification in rats

实验性血管钙化大鼠血浆的抗氧化能力的研究

The Research of the Ability of the Anti-oxidation in Plasma in Experimental Rats

应用茜素红染色观察血管钙化情况。

Vascular calcification were observed by Alizarin red stain .

终末期肾功能衰竭患者血管钙化发生事件分析

Analysis of occurrence of vascular calcification in kidney failure patients at late stage

血管钙化对血管组织内皮素表达的影响

Effects of Vascular Calcification on Endothelin Expression in Vessel

转鲑鱼降钙素基因酵母对骨质疏松和血管钙化作用的研究

Research on the Effect of Salmon Calcitonin Transformed Yeast to Osteoporosis and Arterial Calcification

血管钙化对大鼠离体胸主动脉环张力的影响

Effects of angiosteosis on the tension of thoracic aortic ring in rats in vitro