血小板源性生长因子

血小板源性生长因子和转化生长因子-β1对大鼠肺成纤维细胞整合素α5β1表达的影响

The effects of PDGF and tgf - β 1 on the expression of integrin α 5 β 1 in rat pulmonary fibroblasts

结论：丹参药膜可通过调节血小板源性生长因子和碱性成纤维细胞生长因子的表达而促进创伤修复，且其作用顺应创伤修复的基本规律。

CONCLUSION : Danshen film can regulate PDGF and bFGF reaction to promote the wound repair , and its effect conforms to the basic law of the wound healing .

糖尿病视网膜病变血浆与房水中血小板源性生长因子B含量的相关研究

Level of platelet-derived growth factor-B in plasma and aqueous humor in diabetic retinopathy

氧化低密度和极低密度脂蛋白对单核细胞血小板源性生长因子B链表达的影响

The Effects of Oxidized Low Density Lipoprotein and Very Low Density Lipoprotein on Platelet Derived Growth Factor B-chain Expression in Monocytes

反义寡核苷酸抑制兔血管平滑肌细胞增殖和血小板源性生长因子βmRNA的表达

An antisense oligonucleotide inhibits the expression of PDGF - β mRNA and the proliferation of rabbit vascular smooth muscle cells

缺氧内皮细胞介导肺动脉平滑肌细胞血小板源性生长因子mRNA表达

Platelet derived growth factor ( PDGF ) mRNA expression of porcine pulmonary artery smooth muscle cells induced by hypoxic endothelial cells conditioned medium

增殖细胞和迁移细胞既有血小板源性生长因子mRNA和其蛋白表达，又有弹性蛋白酶mRNA和其蛋白表达；

The proliferating cells and migrating cells not only expressed PDGF-A mRNA and PDGF-A protein , but also expressed elastase mRNA and elastase protein .

雷公藤红素对大鼠血管平滑肌细胞c-myc和血小板源性生长因子的mRNA的影响

Effect of Tripterine on mRNA Expression of c myc and Platelet Derived Growth Factor of Vascular Smooth Muscle Cell in Rats

目的在体观察重组人血小板源性生长因子（recombinanthumanplatelet-derivedgrowthfactor，rhPDGF）促进糖尿病大鼠全层皮肤缺损创面修复可能涉及的细胞和分子机制，研究其可能涉及的信号通路。

Objective To investigate the possible signaling mechanisms by which recombinant human platelet-derived growth factor ( rhPDGF ) accelerated healing of cutaneous wound in diabetic rats .

血小板源性生长因子α和β受体酪氨酸激酶抑制剂对兔PVR的治疗作用

Therapeutic effect of platelet-derived growth factor α and β receptor tyrosine kinase inhibitor on rabbit proliferative vitreoretinopathy

目的探讨转化生长因子β1（TGF-β1）、血小板源性生长因子（PDGF）、结缔组织生长因子（CTGF）在尘肺病发生、发展中表达水平的变化及其意义。

Objective To explore the TGF - β 1 , PDGF , CTGF serum expression significance in the occurrence and development of pneumoconiosis .

以血小板源性生长因子A和大鼠胰腺丝氨酸弹性蛋白酶的地高辛标记RNA探针进行原位杂交，并用抗5溴脱氧尿嘧啶抗体进行双重染色。

In situ hybridization was performed by the RNA probe of PDGF-A and rat pancreatic elastase which was labeled with digoxin , and the double immunostaining for 5-bromo-2 ' - deoxyuridine ( BrdU ) was performed .

目的：了解血小板源性生长因子（PDGF）和碱性成纤维细胞生长因子（bFGF）在视网膜增殖膜细胞的表达及其与增殖性玻璃体视网膜病变（PVR）的关系。

Objective : To study the role of platelet derived growth factor ( PDGF ) and basic fibroblast growth factor ( bFGF ) which play in PVR .

近10年来，大量的肿瘤血管形成的内源性生长因子已在体内外实验中得到证实，血小板源性生长因子（PDGF）与肿瘤血管的生成，血管的发育成熟关系比较密切。

Many endogenous growth factors relating to tumor angiogenesis have been characterized in vivo in the past decade , including platelet-derived growth factor ( PDGF ) .

连续28d观察眼底PVR分级情况，检测玻璃体中碱性成纤维细胞生长因子（Basicfibroblastgrowthfactor，bFGF）、血小板源性生长因子（platelet-derivedgrowthfactor，PDGF）浓度。

The ocular fundus of PVR grade was observed for continuous 28 days , and the concentrations of basic fibroblast growth factor ( bFGF ) and platelet-derived growth factor ( PDGF ) in vitreous body were detected .

血小板源性生长因子（platelet-derivedgrowthfactor，PDGF）是由多种细胞产生的肽类生长因子，它在组织修复、胚胎发育、免疫以及多种常见疾病中起着重要作用。

Platelet-derived growth factor ( PDGF ) is a peptide growth factor produced by many kinds of cells , and it plays a significant role in tissue repair , embryonic development , immunization and many common diseases .

目的：研究血小板源性生长因子（Platete-derivedgrowthfactor，PDGF）对体外培养的子宫肌瘤细胞和子宫平滑肌细胞增殖性核抗原（PCNA）和细胞内前胶原α1多肽的表达的影响。

Objective : To explore the effect of platelet-derived growth factor ( PDGF ) on the proliferative cell nuclear antigen ( PCNA ) activity and the expression of collagen α 1 (ⅰ、ⅲ) in the primary uterine leiomyoma cell cultures in vitro .

目的探讨膀胱移行上皮细胞癌（BTCC）组织中血小板源性生长因子受体（PDGFR）及癌蛋白c-Fos（c-Fos）的表达与BTCC的关系。

Objective To elucidate the relation of platelet-derived growth factor receptor ( PDGFR ) and c-Fos protein expressions with human bladder transitional epithelial cell carcinoma ( BTCC ) .

目的：研究血浆血小板源性生长因子（PlateletDerivedGrowthFactor，PDGF）及病变区PDGFA，B链表达在化学性肝纤维化不同病理阶段的动态变化。

Objective : Our purpose was to study the dynamic alteration of plasma platelet derived growth factor ( PDGF ) and the expressions of A and B chains of PDGF in the abnormal area of liver in the different pathologic stages of cirrhosis .

目的：探讨血小板源性生长因子受体（PDGFR）的表达与肾细胞癌之间的关系。

Objective : To elucidate the relationship between the expression of platelet-derived growth factor receptor ( PDGFR ) and human renal cell carcinoma .

目的：研究在血小板源性生长因子（PDGF）和白介素-1β（IL-1β）作用下苏拉明（suramin）对培养的人视网膜色素上皮（retinapligmentepithel-um，RPE）细胞增殖的影响。

· AIM : With the effect of PDGF and IL-1 , investigate effects of suramin on proliferation of cultured human retinal pigment epithelial ( RPE ) cells in vitro .

目的观察局部应用血小板源性生长因子B链（plateledderivedgrowthfactorBB，PDGF-BB）对韧带愈合质量的影响。

Objective To examine an effect of the locally-used platelet derived growth factor-BB ( PDGF-BB ) on the healing of the medial collateral ligament ( MCL ) in the knee joints of rats .

术后30d丹参药膜组血小板源性生长因子的表达与全身用药组比较差异无显著性意义（P>0.05）；

There was insignificant difference in the expression of PDGF in the danshen film group as compared with the systemic administration group at day 30 after operation ( P > 0.05 ) .

目的研究低氧直接或通过内皮细胞的介导对体外培养的肺血管周细胞的能量代谢、细胞周期和血小板源性生长因子（PDGF）及其受体mRNA表达的影响。

Objective To study the effects of hypoxia , directly or mediated by pulmonary arterial endothelial cells , on energy metabolism , cell cycle , platelet derived growth factor ( PDGF ) and PDGF receptor mRNA expression of vascular pericytes of the lung in vitro .

目的探讨隆凸性皮肤纤维肉瘤（DFSP）中CD34、血小板源性生长因子受体（PDGFR-β）的表达及基因倍体的意义。

Objective To investigate expression of CD34 and platelet derived growth factor receptor β ( PDGFR - β) and pattern of DNA ploidy in dermatofibrosarcoma protuberans ( DFSP ), and to study their significance and relationship .

目的：研究鼻内镜术后术腔愈合与鼻腔分泌液中血小板源性生长因子（PDGF）、肿瘤坏死因子α（TNF-α）、透明质酸（HA）的关系。

Objective : To investigate the relation of healing outcomes and three factors in nasal fluid before and after endoscopic sinus surgery ( ESS ), including platelet derived growth factor ( PDGF ), tumour necrosis factor - α( TNF - α) and hyaluronic acid ( HA ) .

同时TGF-βs还可刺激多种细胞因子的产生，并与这些细胞因子协调作用，如与PDGF（血小板源性生长因子）和FGF（成纤维细胞生长因子）共同刺激成纤维细胞增殖和合成胶原。

Meanwhile , TGF - β S can induce production of various cytokines such as PDGF ( platelet derived growth factor ) and FGF ( fibro-blast growth factor ) , exert effects on proliferation of fibroblasts and collagen synthesis with them together .

目的观察不同创面血小板源性生长因子（PDGF）A及其受体（PDGFR）α的动态表达，探讨急性放射性皮肤溃疡难愈合的机制。

Objective To investigate the dynamic expression of platelet-derived growth factor-A ( PDGF-A ) and its receptor alpha ( PDGFR - α) in different acute radiation-induced skin ulcers , and to explore the underlying mechanism involved in retarded healing of the ulcer .

目的观察血小板源性生长因子（PDGF）和转化生长因子β1（TGF－β1）对大鼠肺成纤维细胞整合素（integrin）α5β1及其配体纤维连接蛋白（FN）合成的影响。

PURPOSE To observe the expression of integrin α 5 β 1 and its ligand fibronectin ( FN ) of rat pulmonary fibroblasts ( PFbs ) treated by platelet-derived growth factor ( PDGF ) and transforming growth factor β 1 ( TGF - β 1 ) in vitro .

血小板源性生长因子（PDGFs）属糖蛋白二聚体（分子量27000~35000）家族，它向间质源细胞施以有力的促有丝分裂和趋化活性活动。

Platelet-derived growth factors ( PDGFs ) are a member of family of glycoprotein dimers ( Mr 27000 ~ 35000 ) that exert potent mitogenic and chemotactic activities toward cells of mesenchymal origin .