致突变

采用鱼类致突变实验、鱼类红、白血球计数等方法，测定外周血白细胞数、红细胞微核和核异常以及肝脏过氧化氢酶（CAT）活性。

The methods of the mutagenesis test and red and white blood cells counting in fish were used to assay the white cell number , micronuclei and nuclear abnormity of red cell in peripheral blood erythrocytes , and CAT activity of liver in Monopterus albus .

结果：nHAC的浸提液各剂量组对鼠伤寒沙门菌的致突变比值均小于2，nHAC不会引起鼠伤寒沙门菌的回复突变数增加。

Results : The mutagenesis rates of murine typhoid salmonella in the experimental groups of all dosage levers were less then 2 , and nHAC would not cause the increase of the back mutation in murine typhoid salmonella .

双链DNA直接测序法在环境诱变剂致突变分子机制研究中的应用Ⅰ.非突变质粒抗性基因片段的序列测定

Application of directly sequencing for double strand DNA in research of enviromental mutagens

多环芳烃DNA加合物致突变作用研究

Studies on Mutagenicity of Polycyclic Aromatic Hydrocarbon DNA Adduct

非程序DNA合成法评价厨房油烟凝聚物致突变作用

The assessment of mutagenicity of cooking oil fume condensate in kitchen by uds-test

银染mRNA差异显示方法在致突变实验中的初步应用

Preliminary Application of mRNA Differential display with Silver Staining in Studying Mutagenesis

用3种方法检测Q流域地面水致突变活性

Detection of Mutagenicity of Q River Surface Water by Three Methods

目的为了调查Q流域地面水致突变性。

Objective To investigate the mutagenicity of Q river surface water .

错配PCR致突变的实验条件研究

The condition for error - prone PCR induced mutation

mRNA差异显示法筛选环磷酰胺致突变相关基因的初步研究

Preliminary Study on Cyclophosphamide-Mutagenesis Related-Gene with mRNA Differential Display

常规饮用水处理法及维生素C对农村饲养业排出物中致突变物作用的研究

A preliminary study of the effects of routine drinking water treatment and vitamin C on fowl and livestock fecal mutagenicity

~（60）Coγ线辐照的油菜花粉致突变活性研究

Studies on mutagenic activity of ~ ( 60 ) co γ - ray irradiated rape pollen

目的：研究无花果提取液（figextract，FE）致突变及抗突变效应。

Purpose : To study the mutagenic and antimutagenic effects of fig extract ( FE ) .

SOD富硒枸杞对烹调胡麻油烟冷凝物致突变的拮抗作用

Antagonistic Effects of SOD-Selenium-enriched Wolfberry Fruits on Mutagenicity of Siritch Vapor Condensate in Mice

运用RAPD技术检测除草剂对草鱼的致突变作用

Detection on Mutagenicity of Herbicides to Grass Carp by RAPD Technique

目的：观察Dip的致突变毒性。

Aim : To investigate the mutagenic toxicity of Dip .

适用于检测能引起DNA链断裂的间接致突变物和致癌物。

And , FADU is also suita - ble for the detection of DNA strand breaks caused by indirect mutagens and carcinogens .

结论柴油机排气微粒有机可溶成分中的直接致突变物对细胞DNA具有明显的损伤作用。

Conclusion The direct acting mutagens in soluble organic fraction ( SOF ) of diesel exhaust particulates could remarkably damage the DNA of cells .

结果表明：氯化样品的致突变活性与藻类代谢物含量及加氧量均呈正相关（P＜0.05）；

The results showed that the mutagenic activity of chlorinated samples was positively correlated with the concentration of algal metabolites and chlorine ( P < 0 . 05 ) .

锌对致突变物诱发的CHO细胞突变的影响

The Effects of Zinc on the Mutation in CHO Cells by Mutagens

苯酚类化合物致突变Ames试验研究

Study on the mutagenicity of phenolic compounds by the Ames test

Ames试验MR＜2，显性致死试验、致突变指数与阴性对照组比较无显著差异（P＞0.05）均显示阴性反应。

Results also showed negative response , both in Ames test ( MR < 2 ) and in dominant-lethal test ( P > 0.05 ) .

方法应用Ames试验、小鼠骨髓微核试验对秦皮总香豆素进行了致突变研究。

Methods Ames test and the micronucleus test in mice were applied .

研究表明这种突变是在DNA或DNA的转录水平上发生的。用S1可以简便、快速、灵敏地检测出EB的致突变作用。

The mutagenesis of EB could be detected with S1 dark variant , and this method was simple , rapid and sensitive .

硫芥的毒物动力学Ames试验检测硫芥的致突变作用

Study on mutagenicity of sulfur mustard by Ames test

微核、精子畸形和Ames试验表明无致突变作用。

Micronucleus assay , sperm deformity assay and Ames assay are not mutagenesis ;

各项致突变试验结果均表明HUN无致突变性，是一种较理想的植物杀虫剂。

HUN has no mutagenicity and is an efficacious plant insecticide .

大气污染物致突变研究中的Breakpoint回归

Breakpoint Regression in Research of Airborne Particulate Genotoxicity

提示LPG燃烧产物接触者尿中致突变物主要是以葡萄糖醛酸贰结合状态存在的芳香胺类物质。

This suggests that the mutagenic compounds presented in the urine samples are mainly aromatic amino compounds as glucuronide conjugates .

采用单细胞凝胶电泳池（彗星试验）检测有机可溶成分中的直接致突变物对细胞DNA的损伤作用。

The damage effect of the direct acting mutagens in SOF of diesel exhaust particulates on DNA of cells was analyzed with single cell gel electrophoresis assay ( Comet assay ) .