致病作用

目的探讨肾组织中乙型肝炎病毒（HBV）DNA和RNA的存在及其致病作用。

Objective To study the presence and pathogenesis of hepatitis B virus ( HBV ) DNA and RNA in renal tissues .

但是，由于目前对C.jejuni的遗传学特性、毒力因子、致病作用和C。

However , due to the poor understanding of genetic property , virulence factors and pathogenesis of C.

细菌脂多糖、脂蛋白和DNA体内协同致病作用观察

Synergistic pathopoiesis effects of lipopolysaccharide , bacterial lipoprotein and bacterial DNA in vivo

通过在体实验，首次进一步观察了细菌LPS、细菌脂蛋白和细菌DNA对小鼠的协同致病作用。

The synergistic effects of LPS , BLP and bacterial DNA were investigated in vivo for the first time .

目的研究急性脑梗死血小板蛋白激酶C（PKC）对血小板活性的影响及其致病作用。

Objective To study platelet protein kinase C ( PKC )′ s effect on platelet activity and its role .

其次，观察了LPS、BLP和细菌DNA体内协同致病作用；

To examine the synergistic effects of LPS , BLP and bacterial DNA in mice ;

TNF-α、HA和LN对股骨头缺血性坏死致病作用的研究

The Pathogenic Effect of TNF - α, HA and LN on Ischemic Necrosis of The Femoral Head

节瘤拟杆菌是致病作用的主要病菌之一，它是通过IV型纤毛和细胞外蛋白酶而产生作用。

The major virulence factors that have been implicated in the disease are type IV fimbriae and extracellular proteases .

大豆根腐病菌（fusariumoxysporum）毒素及其对大豆根部致病作用的研究

Studies on Fusarium Oxysporum toxin and Its Effects on Soybean Root

研究目的：冠状动脉（CA）微循环的结构和功能异常在许多心血管疾病中起着致病作用，并有预后意义。

Objectives : The structural and functional abnormalities of coronary microcirculation play a pathogenic role in many cardiovascular diseases , and have a prognostic significance .

目的研究血小板激活因子（platelet-activatingfactor，PAF）在缺血性脑损伤中的致病作用。

Objective To study the pathogenic effect of platelet activating factor ( PAF ) on ischemic brain injury .

本文对大肠杆菌内毒素（LPS）在实验性早期和晚期肝硬化中的致病作用进行了研究。

The effect of E. coli endotoxin ( LPS ) on early and advanced experimental cirrhosis have been studied .

目的了解自身反应性T淋巴细胞（ART）在自身免疫性肾小球肾炎中的可能致病作用，探讨肾脏自身免疫性损伤与致肾炎性ART存在的相关性。

Objective To understand the effect of auto-reactive T lymphocytes ( ART ) on pathogenesis of autoimmune glomerulonephritis , and study the relationship between the existence of pathogenic ART and autoimmune renal injury .

目的：建立慢性铜绿假单胞菌（PA）肺部感染动物模型，研究铜绿假单胞菌对肺组织的致病作用。

Objective : To study the pathogenic role of pseudomonas aeruginosa ( PA ) in the pulmonary infection in aged patients .

[结论]联合抗过敏疗法对急性乙型肝炎疗效显著，从而间接证明了免疫球蛋白E及其介导的Ⅰ型变态反应在急性乙型肝炎发病机理中的致病作用。

CONCLUSION The combination antiallergenic therapy is useful for treating patients with acute hepatitis B , and type I allergenic reaction may play a role in the pathogenesis of acute hepatitis B.

目的探讨粘附分子P选择素（CD62P）在紫癜性肾炎（HSPN）患者中的致病作用。

Objective To investigate the role of adhesion molecules P-selectin ( CD62P ) as a pathogenic factor in Henoch-Schonlein purpura nephritis ( HSPN ) patients .

目的为探讨氧化型低密度脂蛋白（Ox-LDL）对动脉粥样硬化的致病作用和临床意义。

Objective To approach into the pathogenetic effect of oxidized low density lipoprotein ( Ox-LDL ) atherosclerosis and its clinical significance .

目的了解黄石地区STD门诊患者泌尿生殖道解脲支原体（Uu）、人型支原体（Mh）的致病作用，并研究其耐药情况。

Objective To understand the pathopoiesis of Uu , Mh , of genitourinary and drug resistance of Uu , Mh in STD patients in Huangshi area .

目的探讨肥大细胞（mastcell，MC）在重症急性胰腺炎（SAP）时的致病作用，了解肥大细胞膜稳定剂对SAP的治疗作用。

Objective To investigate the pathogenic role of mast cell ( MC ) in the course of severe acute pancreatitis ( SAP ) and the therapeutic effect of mast cell membrane stabilizer on SAP .

结论：2型糖尿病患者存在急性时相反应，CRP在2型糖尿病的发生、发展中具有致病作用。

Conclusion Patients with type 2 diabetes mellitus exist acute phase reaction and CRP has the pathogenic effect during the course of arising and development of type 2 diabetes mellitus .

为研究喉癌与人乳头状瘤病毒（HPV）感染的关系，本研究探讨了HPV在喉癌中的致病作用和基因组型的分布与表达。

In older to study the interrelationship between laryngeal carcinoma and human papillomavirus ( HPV ) . The distribution and expression of genome types of HPV in laryngeal carcinoma were investigated .

目的了解TTV在我院非甲-庚型肝炎患者中的感染状况。研究TTV感染对非甲-庚型肝炎临床表现的影响，探讨TTV在病毒性肝炎中的致病作用。

Objective To study TTV infection in patients with non A - C hepatitis , its clinical process and its role in pathogene-sis of viral hepatitis .

目的：探讨同型半胱氨酸（Hcy）代谢相关酶N5,10亚甲基四氢叶酸还原酶（MTHFR）及胱硫醚β合酶（CBS）基因突变对脑梗死的致病作用。

Aim : To study the effect of gene mutations of methylenetetrahydrofolate reductase ( MTHFR ) and cystathionine β - synthase ( CBS ) in cerebral infarction .

结论部分血清HBV标志物阳性的成人肾炎患者肾组织存在HBVdna，提示HBV感染与其肾炎发病有关，HBV可能对肾脏有直接致病作用。

Conclusion HBV DNA existed in renal tissue in GN adults with positive serum HBV marker , suggesting etiological relation to HBV infection in these patients , and renal lesions due to HBV may be the direct outcome of HBV invasion .

近年来随着对MDS进行的更为广泛而深入的研究，发现在MDS的疾病过程中，越来越多的基因异常起着不同的致病作用。

Nowadays , following the extensive and penetrating research of MDS , we find in the disease process of MDS , more and more gene dysfunction have effectiveness to the pathopoiesis .

氧化应激、OIR对T2DM大鼠的致病作用及胰岛素相关信号通路的调控机制

Pathopoiesis Effects of the Oxidative Stress 、 OIR on the T2 DM and the Regulatory Mechanism of Insulin Related Signal Pathway

因此，在急性心肌梗塞时，评估PTX3是否发挥了致病作用尤其重要。

It was therefore important to assess whether PTX3 plays a pathogenetic role in acute myocardial infarction .

HDV的直接细胞毒性作用在急性肝炎中可能起主要致病作用，在合并有HDV感染的乙型肝炎患者病情加重、病死率增高和慢性化过程中，HDV可能起主要促进作用。

The effects of direct cytotoxicity of HDV on hepatocytes may play a major pathogenic role in acute hepatitis and in aggravating illness status to severe type .

目的探讨空肠弯曲菌（Cj）及其抗体在急性运动性轴索型格林－巴利综合征（AMAN）中的免疫致病作用。

Objective To study the pathogenic effect of campylobacter jejuni ( Cj ) infection and antibody in acute motor axonal form of Guillain-Barre syndrorne ( AMAN ) .

结果：（S）DHPA或/及（RS）DHPA与高压氧联合治疗可抑制人工感染小鼠体内日本乙型脑炎病毒的致病作用。

Conclusion The combined treatment of ( S ) DHPA and / or ( RS ) DHPA and HBO has inhibitory effect on Japanese encephalitis virus infection in experimental mice .