自分泌

VEGF在新生鼠胫骨上端成骨细胞中自分泌作用的研究

Autocrine function of VEGF in osteoblast of proximal tibia of neonatal rat

VEGF既是一种旁分泌因子，又是一种自分泌因子。

In addition of its paracrine function , VEGF is an autocrine factor .

自分泌VEGF对人慢性髓性白血病细胞系K562的作用

Effect of Autocrine VEGF on Chronic Myeloid Leukemia Cell Line K562

结论实验结果提示在血管应激反应过程中，血管组织可能通过局部自分泌、旁分泌方式，释放ET－1、NO调节局部血管舒缩功能。

Conclusion The local vascular tissues may be regulated by autocrine and / or paracrine mechanisms .

TGFβ2不仅通过旁分泌方式，也可通过自分泌方式作用于小梁细胞。

Trabecular meshwork cells were affected by TGF β 2 through paracrine and autocrine action .

结论在白血病细胞异常增殖中自分泌VEGF可能起着重要作用。

Conclusion The autocrine VEGF may play an important role in the abnormal proliferation of leukemic cells .

结论（1）ADM可能既是循环激素，又是自分泌和／或旁分泌激素，在心肌肥厚发生发展中起代偿作用，有望成为评价心肌肥厚严重程度的新的敏感指标。

Conclusion ( 1 ) ADM was probably a circulating hormone .

滋养细胞肿瘤JAR细胞株hCG自分泌作用的研究

Study on hCG Autocrine Function of JAR Cell

子宫内膜癌异位HCG自分泌观察

Autocrine of Ectopic HCG in Endometrial Carcinoma Cell Lines

作为一种重要的血管性因子，VEGF的自分泌作用方式在成骨细胞的分化中起重要作用。

Acting as an important factor of angiogenesis , VEGF might play an important autocrine function during osteoblast differentiation .

目的揭示胃泌素受体（即gastrinreceptor，GR）在胃癌自分泌生长中的作用。

Objective To demonstrate the role of gastrin receptor ( CR ) in autocrine growth of gastric cancer .

[目的]观察阻断转化生长因子β1（TGFβ1）自分泌环对骨肉瘤细胞恶性表型的影响。

[ Objective ] To investigate the effects of TGF β 1 autocrine blockage on the malignant phenotypes of osteosarcoma cells .

[目的]观察子宫内膜癌细胞系异位HCG自分泌现象。

[ Purpose ] To observe the ectopic autocrine phenomenon of HCG in endometrial carcinoma cell lines .

结果表明：大鼠肾系膜细胞能产生活性TGFβ，后者是一种自分泌的生长抑制性因子。

These results demonstrated that the mesangial cell produce active TGF β, which functions as an autocrine growth inhibitor for mesangial cells .

结论VEGF可能是骨髓瘤细胞的一种自分泌因子，同时可作为一种旁分泌因子调控患者骨髓中的血管新生反应。

Conclusion VEGF may be an autocrine factor , concomitantly it modulates the angiogenic reaction in the bone marrow as a paracrine factor .

故淋巴细胞分泌的GH有可能以自分泌和旁分泌的方式影响淋巴细胞的功能。

Lymphocytic GH could affect the function of lymphocyte in an autocrine and / or paracrine way .

结论：横纹肌肉瘤中存在TGFβ1自分泌和旁分泌现象，且肿瘤细胞表达相关受体。

Conclusions There are TGF β 1 autocrine / paracrine pathway in RMS , with the expression of TGF β 1 associated receptors .

结论：表明兔输卵管粘膜上皮细胞自分泌ET-1。

CONCLUSION : Our results indicate that epithelial cells of rabbit 's uterine tube epithelial cells secrete ET-1 .

结论IL-6对PAa细胞生长具有调控作用，IL-6为PAa细胞自分泌生长刺激因子。

Conclusion These results demonstrate that IL 6 acts as an autocrine growth stimulator for PAa cells in vitro .

目的探讨垂体内自分泌、旁分泌因子IL-1β是否参与垂体细胞和垂体瘤细胞的生长增殖过程。

To investigate whether IL 1 β could affect the cell proliferation of normal pituitary cells and ACTH secreting adenoma cells .

NTs的作用除了靶源性方式外，也存在局部的自分泌与旁分泌。

There are local autocrine and paracrine mechanisms besides target derived NTs .

TGFα与细胞表面的表皮生长因子受体（EGFR）结合，以自分泌方式参与肿瘤的形成和生长，具有重要的肿瘤诊断、预后及疗效评估意义。

And known to bind the epidermal growth factor receptor ( EGFR ) on cell surface in due form of autocrine mechanism .

结论：内源性EGF借助于自分泌、旁分泌和内分泌机制促进了深二度烫伤创面愈合。

Conclusion : Endogenous EGF might accelerate second deep degree scald wound healing by the autocrine , paracrine and endocrine mechanism .

血小板生成素是人红白血病HEL细胞自分泌因子的证据

Thrombopoietin is a possible autocrine growth factor of HEL cell line

这种作用体现在局部的旁分泌和自分泌，通过影响卵泡细胞的分化、芳香化酶的活性和cAMP水平等实现对卵泡机能的调节。

This is realized by part of paracrine and autocrine controlling follicular function through the differentiation of follicular cells , activity of aromatizing enzyme and level of cAMP .

VIP对胃癌生长的影响，胃癌细胞是否分泌VIP及存在VIP自分泌调节作用尚有争议。

Whether gastric cancer cells secrete VIP or VIP autocrine regulation exists in the gastric cancer cells has not yet been reported .

阻断自分泌性胃泌素对胃癌SGC-7901细胞增殖和凋亡的影响

Blocking the gastrin / cholecystokinin-B receptor autocrine loop influences the growth and apoptosis of human gastric cancer cells

结论：通过阻断TGFβ1自分泌环以降低骨肉瘤细胞表达的TGFβ1，可以明显抑制肿瘤细胞增殖活性。进一步的深入研究，必将为骨肉瘤疗效的提高开辟新的研究方向。

Conclusion : To block the TGF β 1 autocrine loop of osteosarcoma cells could inhibit cell proliferation , which might be helpful for gene therapy of osteosarcoma .

实验结论提示Tpo可能是HEL细胞的自分泌因子。

It was concluded that Tpo may be a possible autocrine factor of HEL cells .

研究表明，VEGF不仅以旁分泌的形式促进肿瘤血管的生成，也可能通过自分泌形式作用于肿瘤细胞自身的VEGF受体而促进肿瘤细胞生长。

Some studies have demonstrated that VEGF have not only paracrine effect upon the endothelial cell to promote angiogenesis , also an autocrine effect upon the tumor cell receptor itself .