腺苷酸环化酶

缺血心肌细胞膜β肾上腺素能受体、腺苷酸环化酶和cAMP水平的放射配基分析

Radioligand Assay on β - adrenoreceptor , AC and cAMP Levels During Myocardial Ischemia

跨膜Ca~（2＋）梯差通过调节膜脂流动性影响Gs激活腺苷酸环化酶

Regulation of transmembrane ca ￣( 2 + ) gradient by affecting membrane fluidity on the stimulation of adenylate cyclase activity by g_s

姜黄素对慢性应激大鼠不同脑区cAMP水平及腺苷酸环化酶活性的影响

Effects of Curcumin on cAMP Content and Adenylate Cyclase Activity in Brain Regions of Chronically Stressed Rats

发育因素影响心肌β－AR对腺苷酸环化酶的调节。

The developmental factors exert effect on the β - AR modulation of adenylate cyclase in rat myocardium .

吗啡依赖小鼠脑组织cAMP系统的变化及腺苷酸环化酶磷酸化调节

Changes of AC / cAMP System and Phosphorylation Regulation of Adenylate Cyclase Activity in Brain Regions from Morphine dependent Mice △

腺苷及其受体诱导细胞凋亡的机制主要涉及腺苷酸环化酶（AC）、cAMP、Ca2+等。

The proapoptotic mechanisms of adenosine and its receptors are involved in Adenylyl cyclase ( AC ), cAMP , Ca 2 + , etc.

Dex对血小板钙调素（CaM）和腺苷酸环化酶（AC）活性，以及对cAMP和cGMP的生成均无明显影响。

The activity of CaM and AC , the production of cAMP and cGMP were not affected by Dex .

石斑鱼垂体腺苷酸环化酶激活多肽和生长激素释放激素基因的cDNA克隆及表达分析（英文）

Sequence and Expression of a cDNA Encoding Both Pituitary Adenylate Cyclase Activating Polypeptide and Growth Hormone-releasing Hormone in Grouper ( Epinephelus coioides )

此外，Gβγ对细胞内定位，调节受体功能，活化磷脂酶Cβ，影响受体激酶和腺苷酸环化酶活性等都起到重要作用。

In addition , G βγ dimers plays important roles on the intracellular localization , regulating receptor function , influencing the activities of phospholipase C β, receptor kinase , and adenylate cyclase .

当该细胞质膜上的PTH受体与PTH结合后，可激发腺苷酸环化酶（AC）的活性。

The binding of PTH with its receptor on ROS cell will stimulate adenylate cyclase activity ( AC ) .

本文报道腺苷酸环化酶（AC）和环腺苷酸磷酸二酯酶（PDE）比活力的放射性同位素测定法。

A method was developed for determination of adenylate cyclase ( AC ) and cAMP phosphodiesterase ( PDE ) specific activities by radioisotopic assay .

目的研究慢性吗啡处理的大鼠停药后不同时间部分脑区腺苷酸环化酶Ⅷ（ACⅧ）基因表达水平的变化。

Objective To explore the changes of adenylate cyclase ⅷ ( AC ⅷ) gene expression in defined brain areas of rats at the selected time points after chronic morphine exposure .

方法利用酵母双杂交和自行构建的酵母三杂交系统分别研究G（β1）和G（β1）γ2与腺苷酸环化酶Ⅱ（ACⅡ）的相互作用。

Methods We investigated the interactions of G_ (β 1 ) and G_ (β 1 )γ 2 with adenylyl cyclase ⅱ ( AC ⅱ ) using the yeast two-hybrid and three-hybrid systems .

β受体密度降低和腺苷酸环化酶活性下降导致的cAMP合成减少可能是造成肾上腺素能β受体反应性下降的分子基础。

The decrease of cAMP level caused by reduced receptor density and adenylyl cyclase activity might be the molecular mechanisms underlying the changes of β - adrenergic responsiveness .

钙-钙调蛋白敏感的腺苷酸环化酶1（adenylylcyclase1，AC1）和cAMP信号通路可能介导了这些反应。

Calcium-calmodulin sensitive adenylyl cyclase 1 and cAMP signal pathways likely mediate these effects .

本文介绍了RGS蛋白对阿片受体-腺苷酸环化酶活性的调节；

The modulation of RGS protein on opioid receptor and adenyl cyclase ;

RGS蛋白对阿片受体信号转导途径中腺苷酸环化酶活性的影响

Regulations of RGS Proteins on Activity of Adenylate Cyclases Associated with Opiate Receptors

探讨了鱼油对大鼠心肌细胞膜上β-受体和腺苷酸环化酶（adenylatecyclase，AC）活性的影响。

Effects of fish oil on B-adrenoceptors as well as the activity of adenylate cyclase ( AC ) on rat myocardial membrane were investigated .

目的：比较腺苷酸环化酶（AC）和磷酸二酯酶（PDE）在活动力正常和活动力低下的人精子表达的差异。

Objective : To compare the differences of expressions of adenylyl cyclase ( AC ) and phosphodiesterase ( PDE ) in ejaculated spermatozoa between healthy volunteers and the patients with asthenospermia .

AA增高可激活鸟苷酸环化酶、抑制腺苷酸环化酶，使cGMP增多，cAMP减少而引起表皮细胞增殖。

Elevation of AA may activate the guanyl cyclase and inhibit the adenyl cyclase , causing increase in cGMP and decrease in cAMP , and hence cause proliferation of epidermal cells .

ZP与精子质膜上的受体结合后，可以调节腺苷酸环化酶（AC）的活性，使cAMP浓度升高并激活蛋白激酶A（PKA）。

ZP binding to receptors in the plasma membrane can regulate adenyl cyclase ( AC ) leading to elevation of cAMP and protein kinase A ( PKA ) activation .

在NE系统中，由β2肾上腺素受体（β2-AR）、腺苷酸环化酶（AC）及第二信使环磷酸腺苷（cAMP）组成的信号通路始终是研究焦点。

NE mediated signal transduction pathway consists of β 2-adrenergic receptor ( β 2-AR ) , adenylyl cyclase ( AC ) and second messenger cyclic adenosine monophosphate ( cAMP ) .

胶原酶和DNA酶联合消化法分离SD大鼠胰岛，采用MilliporeMultiscreen系统观察不同浓度垂体腺苷酸环化酶激活肽38（PACAP38）对胰岛功能的影响。

The islets were isolated from SD rats by collagenase and DNase digestion . Millipore Multiscreen assay system was used to observe the effects of pituitary adenylate cyclase activating polypeptide-38 ( PACAP-38 ) on the function of isolated islets .

腺苷酸环化酶激活剂Forskolin促背根节神经突起生长作用的研究

The Study for Effect of an Activator of Adenylyl Cyclase Forskolin on Neurite Outgrowth of Dorsal Root Ganglion

本文用氧化铝层析分离、纯化cAMP测定腺苷酸环化酶（AC）活性的方法，观察了Mg~（2+）和Ca~（2+）对兔心肌质膜AC的影响。

The effects of Mg ~ ( 2 + ) and Ca ~ ( 2 + ) on adenylate cyclase in rabbit heart were . studied with the methods of separation and purification of cAMP by alumina column chromatography .

RGS蛋白对阿片受体-腺苷酸环化酶的调节及阿片受体对钾通道调节的研究进展

The progress about the modulation of RGS protein on opioid receptor-adenyl cyclase and the influence of opioid receptor on potassium channel

在包括人在内的血管细胞中，ADM是腺苷酸环化酶非常有效的激活剂，其作用强于降钙素基因相关肽（CGRP）。

In the vascular smooth muscle cells including human , ADM is a much more efficacious activator of adenylate cyclase and a much more effective relaxant than calcitonin gene-related peptide ( CGRP ) .

结论老年人膀胱逼尿肌的β受体反应性cAMP水平显著下降，腺苷酸环化酶活性的下降和抑制性G蛋白Gi的活性提高可能是其生化基础；

Conclusions There is age-related decline in the β - adrenergic responsive cAMP level of detrusor muscle of the aging ; reduced activity of adenylyl cyclase and enhanced activity of inhibitory G protein Gi may be the biochemical basis ;

为利用基因工程技术获得垂体腺苷酸环化酶激活肽（Pituitaryadenylatecyclaseactivatingpolypeptide，PACAP），根据大肠杆菌的密码偏好性，设计并人工合成编码38个氨基酸的PACAP基因。

To produce pituitary adenylate cyclase activating polypeptide ( PACAP ) using gene engineering technology , a gene coding PACAP was designed and synthesized according to the preference of E.

高亲和性结合位点（对NEM敏感）调节腺苷酸环化酶活性，而对NEM相对不敏感的低亲和性位点则不直接参与该酶活性的调节；

It seemed to be that the high affinity GTP binding sites which were sensitive to NEM modulated the activity of adenylate cyclase ;