腺相关病毒载体

通过应用含有PDX-1基因的重构腺相关病毒载体可以转导PDX-1在C2C12细胞中表达，且可以提高C2C12分化为胰岛素分泌细胞的分泌量。

Recombinant AAV vector carrying PDX-1 can not only transduce PDX-1 gene into C2C12 cells , but also increase insulin excretion of insulin-secreting cells differentiated from C2C12 cells .

通用型四环素调控腺相关病毒载体的构建及其治疗帕金森病的应用研究

The construction of general tetracycline-regulatable AAV vectors and the study of its application in genetic therapy of PD

肝癌特异性p53基因腺相关病毒载体的构建

The construction of a hepatoma-specific adeno-associated virus vector carrying p53 gene

晚期糖化终产物受体反义RNA腺相关病毒载体的构建及在肾脏系膜细胞中表达

Construction of recombinant RAGE antisense RNA adeno-associated virus vector and its expression in rat mesangial cell

用腺相关病毒载体介导人血管内皮生长因子受体KDR胞外区基因的表达

Expression of Extracellular Domain of VEGF Receptor KDR with Recombinant AAV

通用腺相关病毒载体构建及表达报告基因GFP的研究

Construction of a General Adeno-associated Virus Vector and GFP Expressing in Rat Astrocytes Transduced by the rAAV Vector

携反义mrp和mdr1双耐药基因的重组腺相关病毒载体的构建与鉴定

Construction of Recombinant Adeno-associated Virus Vectors Carrying Double Gene of Antisense Multidrug Resistance-associated Protein and Antisense Multidrug Resistance

[方法]：1、KiSS-1腺相关病毒载体构建。

To construct vectors based on adeno-associated virus carrying KiSS-1.2 .

NOS反义RNA重组腺相关病毒载体（rAAV-AsnNOS、rAAV-AsiNOS）抑制缺血缺氧神经细胞凋亡的体内外实验研究

Study on Inhibition of Neuronal Apoptosis Induced by Hypoxia / ischemia Through rAAV Vector Delivery of NOS Antisense RNA ( rAAV-Asn NOS and rAAV-Asi NOS ) in Vivo and in Vitro

目的：构建及鉴定载入金属蛋白酶组织抑制因子1（TIMP鄄1）的重组腺相关病毒载体。

Objective : To construct and identify recombinant adeno-associated virus encoding rat tissue inhibitor of metalloproteinase-1 ( TIMP-1 ) full length cDNA .

目的构建重组人前脑啡肽原基因（hPPE）腺相关病毒载体（AAV）。

Objective To construct the recombinant adeno-associated virus vector with human preproenkephalin gene ( rAAV-hPPE ) .

腺相关病毒载体介导的Endostatin及K1-5蛋白抗肿瘤血管生成协同作用

Synergy of antiangiogenesis for tumor via adeno - associated viral vector - mediated gene transfer of endostatin and K1-5

腺相关病毒载体介导的PLB基因反义RNA对大鼠心肌细胞肌浆网Ca~（2+）-ATPase活性和[Ca~（2+）]i的作用

Effects of phospholamban antisense RNA on SR Ca ~ ( 2 + ) - ATPase and [ Ca ~ ( 2 + ) ] I in rat cardiomyocytes by adeno-associated virus vector

腺相关病毒载体AAV-hVEGF（165）的构建及hVEGF（165）与TGFβ1对椎间盘纤维环细胞的生物学效应

The Construction of AAV-hVEGF_ ( 165 ) and the Biological Effect of hVEGF_ ( 165 ) and TGF β 1 in Annulus Fibrosus Cell of Intervertebral Disc

目的研究以腺相关病毒载体的反义血管内皮细胞生长因子（VascularEndothelialGrowthFactor，VEGF）基因转染对视网膜母细胞瘤（retinoblastoma，RB）细胞中VEGF表达的影响，探讨基因治疗RB的新方法。

Objective To investigate the effect of antisense vascular endothelial growth factor ( VEGF ) gene transfection on the expression of VEGF in retinoblastoma cell by means of adeno-associated virus-mediated vector in vitro and to explore a new gene therapy strategy for retinoblastoma .

目的探讨重组人组织型激肽释放酶（HK）基因腺相关病毒载体（rAVV/HK）对体外培养的人脐静脉内皮细胞（HUVECs）作用。

Objective To investigate the effect of recombinant aden o-associated virus vector ( AVV ) expressing the human tissue kallikrein ( HK ) ge ne ( rAVV / HK ) on human umbilical vein endothelial cells ( HUVECs ) in vitro .

目的构建腺相关病毒载体（pWP8A）与人α1干扰素（hIFNα1）基因重组体。

Objective To construct a recombinant of adeno-associated virus vector ( pWP8A ) and human interferon alphal ( hIFN α 1 ) gene .

构建含有Tet基因调节系统及自杀基因HSVtk的重组腺相关病毒载体pAAVTREHSVtkTetOn，并使用PCR技术和限制性内切酶消化进行鉴定。

In order to investigate the application of recombinant adeno-associated virus ( rAAV ) vector containing Tet regulation system and HSVtk gene in cancer gene therapy , pAAV / TRE / HSVtk / Tet-On was constructed and identified with PCR and restriction enzyme digestion .

白细胞介素4反义基因腺相关病毒载体质粒的构建及鉴定

Construction and Identification of Adeno-associated Virus-based Plasmid Carrying Antisense IL-4

一种高效快速浓缩腺相关病毒载体的方法

A Method of Efficiently and Rapidly Condensing Adeno - associated Viral Vector

睫状神经营养因子腺相关病毒载体的构建

Construction of Adeno-associated Virus Vector of Ciliary Neurotrophic Factor Gene

反义白介素4重组腺相关病毒载体气道给药对哮喘大鼠的影响

Effects of recombinant adeno-associated virus-antisense IL-4 on asthmatic rats by airway delivery

腺相关病毒载体在眼病基因治疗中的应用及研究进展

Progress in gene therapy for eye diseases using adeno-associated virus as a vector

重组腺相关病毒载体在肝疾病基因治疗中的应用及局限性

Application of rAAV in gene therapy of liver diseases

自身互补型腺相关病毒载体发展趋势

Trends in development of self-complementary adeno-associated virus vector

睫状神经营养因子和绿色荧光蛋白共表达的重组腺相关病毒载体的构建

Construction of Recombinant Adeno-associated Virus Vectors Encoding Ciliary Neurotrophic Factor and Green Fluorescent Protein

腺相关病毒载体对心肌细胞感染和外源基因表达的作用

Effect of adeno-associated virus carrier on infection of cardiac myocytes and expression of exogenous genes

不同剂量的重组腺相关病毒载体介导的人血管抑素对糖尿病肾病大鼠肾功能的影响

Effect of different doses of rAAV-AS on the renal function in rats with diabetic nephropathy

不同血清型的重组腺相关病毒载体对成熟肌纤维转导的研究

Efficacy of recombinant adeno-associated virus vectors with different serotypes in the transduction of mature muscle fibers

大鼠星状细胞激活相关蛋白基因的克隆及其重组腺相关病毒载体的构建

Cloning of Stellate Cell Activation-associated Protein ( STAP ) Gene and Construction of Its Recombinant Adenovirus-associated Virus