胸腺嘧啶脱氧核苷

  • 网络TdR;thymidine;H-TdR;dTMP
胸腺嘧啶脱氧核苷胸腺嘧啶脱氧核苷
  1. 并以3H胸腺嘧啶脱氧核苷(3HTDR)细胞内掺入法评价DNA合成量。

    3H TdR incorporation assay in vitro taken was used to evaluate the amount of DNA synthesis .

  2. 3H-胸腺嘧啶脱氧核苷(3H-TdR)掺入法测定单向混合淋巴细胞反应。

    Tritiated thymidine ( 3H-TdR ) was used to measure mixed lymphocyte response .

  3. 目的:探讨卵巢肿瘤中血管内皮生长因子(VEGF)、vEGFmRNA、胸腺嘧啶脱氧核苷磷酸化酶(TP)和TPmRNA的表达及其临床意义。

    Objectives : To study the expression of VEGF , TP and their mRNA in ovarian tumors as well as their clinical significance .

  4. 用3H-TdR(氚标记的胸腺嘧啶脱氧核苷)掺入法结合DNA合成抑制剂处理,研究了纳秒级强脉冲电子束和Ar+离子束诱导的烟草种子的DNA损伤修复合成。

    DNA repair synthesis of tobacco seeds induced by strong pulsed electron and Ar + ion beams was studied with 3H-TdR incorporation method and DNA inhibitor treatment .

  5. 采用氚标记胸腺嘧啶脱氧核苷(3HTDR)掺入法,观察上述各种方法处理后,IEC6的DNA合成率及MAPK活性的变化。

    The changes in DNA synthetic rate and the MAPK activity of IEC-6 after being treated by above agents were assessed by 3H-TdR incorporation method .

  6. 目的:研究卵巢肿瘤中胸腺嘧啶脱氧核苷磷酸化酶(TP)及其mRNA的表达与微血管密度(MVD)的关系及其临床意义。

    Objective : To study the relationship between expressions of TP , TP mRNA and microvessel density ( MVD ) and their clinical significance in ovarian tumors .

  7. 为探讨抗氧化剂维生素E对氧化型低密度脂蛋白致大鼠主动脉平滑肌细胞毒性作用及增殖的影响,以乳酸脱氢酶及3H-胸腺嘧啶脱氧核苷、3H-亮氨酸掺入分别测定平滑肌细胞损伤和增殖。

    Aim To investigate the effect of antioxidant vitamin E ( Vit E ) on the cytotoxicity and proliferation of aortic smooth muscle cell ( SMC ) induced by oxidized low density lipoprotein ( oxLDL ) .

  8. 用3H-TdR(氚标记胸腺嘧啶脱氧核苷)掺入法研究了受低能N+重离子处理的小麦种胚萌发早期DNA的合成动态。

    Using the method of 3H-TdR incorporation , this paper studied the change of DNA synthesis during the early period of germination of wheat seeds irradiated by low energy N + heavy ion .

  9. 目的通过检测乳腺癌标本中胸苷酸合成酶(TS)、胸腺嘧啶脱氧核苷磷酸化酶(TP)、二氟嘧啶脱氢酶(DPD)表达情况,探讨乳腺癌的生物学行为与上述3个指标之间的相关性。

    Objective To investigate the relationships among the expression of thymidylate synthase ( TS ), thymidine phosphorylase ( TP ), and dihydropyrimidine dehydrogenase ( DPD ) and the prognosis of breast cancer .

  10. 方法以细胞分裂标记物胸腺嘧啶脱氧核苷类似物Brdu腹腔注射,采用免疫组织化学方法显示和计数海马Brdu标记阳性细胞;

    METHODS The Brdu positive cells were marked by using the thymidine analog bromodeoxyuridine ( BrdU ), a maker for cataloging cells , then showed and counted by immunohistochemistry .

  11. 胸苷酸合成酶、胸腺嘧啶脱氧核苷磷酸化酶及二氟嘧啶脱氢酶的表达与乳腺癌预后的相关性目的:检测北欧和中国人乳癌患者TP、TS、DPDmRNA水平的差异。

    Aim : To investigate the difference between the mRNA levels of thymidine phosphorylase ( TP ), thymidylate synthase ( TS ), and dihydropyrimidine dehydrogenase ( DPD ) between Chinese and North European breast cancer patients .

  12. 它是一种叶酸依赖性酶,是合成DNA所必需的前体物胸腺嘧啶脱氧核苷(dTMP)的关键酶,在细胞增殖中起重要的作用。

    Thymidylate synthase ( TS ), as a folate-dependent enzyme , is essential to cell proliferation since it is the key enzyme which catalyzes the de novo synthesis of thymidine ( dTMP ) of DNA precursor .

  13. 采用紫外分光光度仪等测定胆管癌细胞QB内NO含量,同时应用3H胸腺嘧啶脱氧核苷掺入法观察一氧化氮对QB增殖的影响。

    The content of NO in cultured cholangiocarcinoma cell QB strain was detected with ultraviolet spectrometry , and the effects of NO on the proliferation of QB cells was detected with 3H TDR incorporation 3 d after culture .

  14. 方法通过体外细胞培养,用14C-胸腺嘧啶脱氧核苷(14C-TdR)、3H-酪氨酸(3H-Tyr)掺入法观察。

    Methods To use incorporation of 14 C-TdR and 3 H-Tyr by cell culture in vitro .

  15. 胸腺嘧啶脱氧核苷亦可能是茶叶中的嘧啶类生物碱与微生物中的核苷类化合物在后发酵过程中缩合形成的。

    On the other hand , deoxythymidine might be derived from the combination of pyrimidine alkaloid in tea leaves with microbial secondary metabolite .

  16. 氚标胸腺嘧啶脱氧核苷掺入实验发现,术后第3天,对照组和实验组氚标胸腺嘧啶脱氧核苷掺入量开始增加,但两组无显著差异(P>0.05);

    Incorporation of ~ 3 H-TdR became higher 3 days later after balloon angioplasty in control group and test group , but there was no significant difference in two groups ( P > 0.05 ) .